PAI Gene Information


Name : orgAb
Accession : NP_457263.1
PAI name : SPI-1
PAI accession : NC_003198_P5
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Virulence
Product : cell invasion protein
Function : -
Note : Similar to C-terminal half of Salmonella typhimurium oxygen-regulated invasion protein OrgA SW:ORGA_SALTY (P40823) (412 aa) fasta scores: E(): 0, 99.5% id in 221 aa, to all of Shigella sonnei Orf10 TR:Q55290 (EMBL:D50601) (231 aa) fasta scores: E(): 6.3e-
Homologs in the searched genomes :   42 hits    ( 41 protein-level,   1 DNA-level )  
Publication :
    -Parkhill,J., "Direct Submission", Submitted (25-OCT-2001) Submitted on behalf of the Salmonalla sequencing team, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18", Nature 413 (6858), 848-852 (2001) PUBMED 11677608.

    -Parkhill,J., Dougan,G., James,K.D., Thomson,N.R., Pickard,D., Wain,J., Churcher,C., Mungall,K.L., Bentley,S.D., Holden,M.T., Sebaihia,M., Baker,S., Basham,D., Brooks,K., Chillingworth,T., Connerton,P., Cronin,A., Davis,P., Davies,R.M., Dowd,L., White,N., , "Direct Submission", Submitted (10-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.


DNA sequence : 
ATGCTCAAAAATATCCCAATTCCGTCCCCGCTTTCGCCTGTTGAGGGGATACTGATAAAGCGTAAAACGCTGGAACGTTA
TTTCTCTATTGAAAGATTAGAACAGCAGGCGCACCAACGGGCTAAGCGTATTTTGCGAGAGGCGGAAGAAGAGGCAAAGA
CCTTGCGGATGTACGCCTATCAGGAAGGTTACGAGCAGGGAATGATAGACGCGTTACAGCAGGTCGCCGCTTATCTTACT
GATAATCAGACAATGGCCTGGAAGTGGATGGAAAAAATACAGATTTATGCCCGCGAGTTATTTTCAGCAGCGGTCGACCA
TCCCGAAACGCTTTTAACCGTCCTGGATGAGTGGCTAAGGGATTTCGATAAGCCGGAGGGGCAACTTTTTTTAACACTGC
CAGTTAATGCGAAAAAAGAACACCAAAAACTGATGGTGTTGCTTATGGAGAACTGGCCTGGCACTTTTAATCTTAAATAT
CATCAGGAACAGCGCTTTATCATGAGTTGCGGCGATCAGATCGCAGAATTTTCACCTGAACAATTTGTTGAAACAGCAGT
AGGCGTCATTAAGCATCATCTTGATGAACTTCCACAAGACTGCCGGACGATTTCTGATAACGCCATTAACGCACTTATTG
ATGAATGGAAGACAAAAACGCAAGCATTGTAA

Protein sequence : 
MLKNIPIPSPLSPVEGILIKRKTLERYFSIERLEQQAHQRAKRILREAEEEAKTLRMYAYQEGYEQGMIDALQQVAAYLT
DNQTMAWKWMEKIQIYARELFSAAVDHPETLLTVLDEWLRDFDKPEGQLFLTLPVNAKKEHQKLMVLLMENWPGTFNLKY
HQEQRFIMSCGDQIAEFSPEQFVETAVGVIKHHLDELPQDCRTISDNAINALIDEWKTKTQAL