Name : ureC (Z1584)
Accession : NP_287088.1
PAI name : TAI
PAI accession : NC_002655_P2
Strain : Escherichia coli 042
Virulence or Resistance: Resistance
Product : urease subunit alpha
Function : -
Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alp
Homologs in the searched genomes : 944 hits ( 944 protein-level )
Publication :
-Perna,N.T., Plunkett,G. III, Burland,V., Mau,B., Glasner,J.D., Rose,D.J., Mayhew,G.F., Evans,P.S., Gregor,J., Kirkpatrick,H.A., Posfai,G., Hackett,J., Klink,S., Boutin,A., Shao,Y., Miller,L., Grotbeck,E.J., Davis,N.W., Lim,A., Dimalanta,E., Potamousis,K.,, "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7", Nature 409 (6819), 529-533 (2001) PUBMED 11206551.
-Perna,N.T., Plunkett,G. III, Burland,V., Mau,B., Glasner,J.D., Rose,D.J., Mayhew,G.F., Evans,P.S., Gregor,J., Kirkpatrick,H.A., Posfai,G., Hackett,J., Klink,S., Boutin,A., Shao,Y., Miller,L., Grotbeck,E.J., Davis,N.W., Lim,A., Dimalanta,E., Potamousis,K.,, "Direct Submission", Submitted (28-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-Perna,N.T., Plunkett,G. III, Burland,V., Mau,B., Glasner,J.D., Rose,D.J., Mayhew,G.F., Evans,P.S., Gregor,J., Kirkpatrick,H.A., Posfai,G., Hackett,J., Klink,S., Boutin,A., Shao,Y., Miller,L., Grotbeck,E.J., Davis,N.W., Lim,A., Dimalanta,E., Potamousis,K.,, "Direct Submission", Submitted (22-OCT-2000) Laboratory of Genetics, University of Wisconsin, 445 Henry Mall, Madison, WI 53706, USA.
| DNA sequence : | |
ATGATGAGTAATATTTCACGCCAGGCCTATGCTGACATGTTCGGCCCTACCACCGGTGATAAAATTCGTCTGGCAGACAC
TGAGCTGTGGATCGAGGTCGAAGATGATTTAACTACCTACGGCGAAGAGGTCAAATTCGGCGGCGGTAAAGTAATCCGCG
ACGGTATGGGACAGGGGCAAATGCTCTCCGCCGGCTGCGCTGATCTGGTGCTGACCAATGCCCTGATCATCGATTACTGG
GGGATCGTTAAAGCCGATATCGGCGTCAAAGATGGAAGGATATTTGCTATCGGCAAAGCCGGTAATCCTGATATACAACC
CAACGTCACTATCCCAATCGGCGTATCCACGGAAATTATTGCCGCAGAAGGCAGGATCGTTACCGCAGGTGGCGTCGATA
CGCATATTCACTGGATCTGCCCACAGCAGGCTGAAGAAGCGCTGACATCCGGCATTACCACCATGATCGGTGGCGGTACT
GGCCCGACAGCGGGTTCTAACGCCACAACCTGTACCCCAGGACCATGGTACATTTATCAAATGCTGCAGGCTGCAGACAG
CCTGCCGGTCAATATCGGGTTGCTGGGTAAAGGCAATTGCTCCAATCCGGATGCGCTTCGTGAGCAGGTCGCGGCCGGGG
TTATCGGCCTCAAAATTCACGAAGACTGGGGAGCTACACCTGCGGTAATCAACTGCGCACTGACTGTAGCCGACGAAATG
GACGTTCAGGTTGCGCTACACAGTGATACGCTTAACGAATCAGGATTCGTTGAGGATACTCTGACTGCCATCGGCGGGCG
CACTATCCATACCTTCCATACAGAAGGTGCAGGTGGTGGTCATGCTCCGGATATTATCACCGCCTGCGCGCACCCCAATA
TTCTGCCTTCCTCAACCAATCCGACGCTACCCTATACCGTCAACACTATTGATGAGCATCTGGACATGCTGATGGTTTGC
CATCATCTTGACCCGGATATCGCCGAGGACGTAGCCTTTGCCGAATCGCGCATTCGCCAGGAAACCATTGCCGCGGAAGA
CGTCCTGCACGACCTTGGCGCGTTCTCCCTCACCTCGTCCGATTCGCAGGCCATGGGACGCGTCGGAGAAGTAGTGTTAC
GAACCTGGCAGGTGGCACACCGGATGAAAGTTCAGCGCGGCCCGTTACCGGAAGAAAGTGGTGATAACGACAACGTCCGC
GTGAAGCGCTATATCGCTAAATACACCATTAATCCGGCATTAACCCACGGTATTGCTCATGAAGTCGGCTCGATTGAAGT
GGGAAAACTGGCGGATCTGGTGCTCTGGTCCCCGGCGTTCTTTGGCGTAAAACCGGCGACTATCGTCAAAGGCGGAATGA
TAGCCATGGCGCCGATGGGTGATATCAACGGCTCTATCCCCACACCGCAGCCGGTGCACTATCGCCCAATGTTCGCTGCA
TTGGGCAGTGCCCGTCACCGCTGTCGTGTGACTTTCCTGTCGCAGGCAGCAGCAGCAAATGGCGTCGCTGAACAGCTTAA
CCTGCACAGCACAACTGCTGTGGTAAAAGGCTGCCGCACAGTACAAAAAGCCGATATGCGCCACAACAGCCTGTTGCCTG
ATATAACCGTGGATTCACAAACCTACGAAGTGCGTATCAACGGCGAACTGATAACCAGTGAACCGGCGGACATTCTGCCA
ATGGCGCAACGTTATTTCCTGTTTTAA
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| Protein sequence : | |
MMSNISRQAYADMFGPTTGDKIRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLSAGCADLVLTNALIIDYW
GIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGVSTEIIAAEGRIVTAGGVDTHIHWICPQQAEEALTSGITTMIGGGT
GPTAGSNATTCTPGPWYIYQMLQAADSLPVNIGLLGKGNCSNPDALREQVAAGVIGLKIHEDWGATPAVINCALTVADEM
DVQVALHSDTLNESGFVEDTLTAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTVNTIDEHLDMLMVC
HHLDPDIAEDVAFAESRIRQETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVVLRTWQVAHRMKVQRGPLPEESGDNDNVR
VKRYIAKYTINPALTHGIAHEVGSIEVGKLADLVLWSPAFFGVKPATIVKGGMIAMAPMGDINGSIPTPQPVHYRPMFAA
LGSARHRCRVTFLSQAAAANGVAEQLNLHSTTAVVKGCRTVQKADMRHNSLLPDITVDSQTYEVRINGELITSEPADILP
MAQRYFLF
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