PAI Gene Information


Name : VC1776 (VC1776)
Accession : NP_231411.1
PAI name : VPI-2
PAI accession : NC_002505_P5
Strain : Vibrio cholerae IEC224
Virulence or Resistance: Not determined
Product : N-acetylneuraminate lyase
Function : -
Note : similar to GB:L42023 SP:P44539 PID:1003186 PID:1222055 PID:1204400; identified by sequence similarity
Homologs in the searched genomes :   49 hits    ( 49 protein-level )  
Publication :
    -Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L., Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.A., Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D., Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I., , "DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae", Nature 406 (6795), 477-483 (2000) PUBMED 10952301.

    -Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L., Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.A., Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D., Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I., , "Direct Submission", Submitted (18-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.

    -Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L., Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.A., Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D., Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I., , "Direct Submission", Submitted (14-JUN-2000) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA.


DNA sequence :
ATGAAAAAATTAACAGGTTTGATTGCTGCTCCACATACGCCTTTCACAAAAGATAACAAGGTTAATTTTGCGGCGATTGA
CCAAATTGCTGAGCTTCTGATTGAACAAGGAGTGAAAGGTGCTTATGTCTGCGGAACGACAGGTGAGGGGATCCATTGCT
CTGTCGAAGAAAGAAAAGCAATTGCAGAACGTTGGGTGAAAGCCGTTGATGGGAAGTTAGATGTTATTTTACATACAGGC
GCTTTAAGTATTGTTGATACCATCAACTTGACAGAGCACGCTGAAACACTGGATATCTTTGCTACCTCCGCTATTGGCCC
ATGCTTTTTCAAACCGGGAAGTGTTGATGATTTAGTTGAGTATTGTGCTCAAGTTGCTGCCGCAGCTCCTTCAAAAGGTT
TTTATTACTACCACTCAGGAATGTCGGGCGTGAATCTAGATTTAGAGCAGTTCTTGATTAAAGGCGAACAGCGCATTCCT
AATCTTTATGGCGCAAAATTCAATAATGCTGATTTGTATGAATACCAGCGTTGCGTGCGAGTATCGAATCGCAAATTTGA
TATTCCATTTGGTGTGGATGAGTTTTTACCTGCTGGTTTAGCCGTCGGTGCGGTAGGCGCAGTTGGTAGCACTTATAACT
ATGCTGCTCCATTGTATTTGAAAATCATTGAAGCATTTAACCATGGTAAACATGATGAAGTCGCAGCGTTGATGGATAAA
GTGATTGCGATTATTCGAGTATTGGTCGAATACGGCGGTGTTGCGGCAGGTAAAGTTGCCATGCAGTTACATGGTATTGA
TGCTGGGGATCCCCGCTTACCTATTCGTTCATTGAATGACAAACAGAAAGCGGATGTGCTTGCGAAGATGCGTGATGCTG
GGTTCCTGTCGATCTAA

Protein sequence :
MKKLTGLIAAPHTPFTKDNKVNFAAIDQIAELLIEQGVKGAYVCGTTGEGIHCSVEERKAIAERWVKAVDGKLDVILHTG
ALSIVDTINLTEHAETLDIFATSAIGPCFFKPGSVDDLVEYCAQVAAAAPSKGFYYYHSGMSGVNLDLEQFLIKGEQRIP
NLYGAKFNNADLYEYQRCVRVSNRKFDIPFGVDEFLPAGLAVGAVGAVGSTYNYAAPLYLKIIEAFNHGKHDEVAALMDK
VIAIIRVLVEYGGVAAGKVAMQLHGIDAGDPRLPIRSLNDKQKADVLAKMRDAGFLSI