Name : orf13/14 (jhp0476)
Accession : NP_223194.1
PAI name : cag PAI
PAI accession : NC_000921_P1
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag island protein
Function : -
Note : similar to H. pylori 26695 gene HP0527
Homologs in the searched genomes : 34 hits ( 33 protein-level, 1 DNA-level )
Publication :
-Alm,R.A., Ling,L.-S.L., Moir,D.T., King,B.L., Brown,E.D., Doig,P.C., Smith,D.R., Noonan,B., Guild,B.C., deJonge,B.L., Carmel,G., Tummino,P.J., Caruso,A., Uria-Nickelsen,M., Mills,D.M., Ives,C., Gibson,R., Merberg,D., Mills,S.D., Jiang,Q., Taylor,D.E., Vov, "Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori", Nature 397 (6715), 176-180 (1999) PUBMED 9923682.
-Alm,R.A., Ling,L.-S.L., Moir,D.T., King,B.L., Brown,E.D., Doig,P.C., Smith,D.R., Noonan,B., Guild,B.C., deJonge,B.L., Carmel,G., Tummino,P.J., Caruso,A., Uria-Nickelsen,M., Mills,D.M., Ives,C., Gibson,R., Merberg,D., Mills,S.D., Jiang,Q., Taylor,D.E., Vov, "Direct Submission", Submitted (13-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA.
-King,B.L., Alm,R.A. and Trust,T.J., "Direct Submission", Submitted (12-JAN-1999) Astra Research Center Boston, 128 Sidney Street, Cambridge, MA 02139, USA.
-Merrell,D.S., Thompson,L.J., Kim,C.C., Mitchell,H., Tompkins,L.S., Lee,A. and Falkow,S., "Growth phase-dependent response of Helicobacter pylori to iron starvation", Infect. Immun. 71 (11), 6510-6525 (2003) PUBMED 14573673.
| DNA sequence : | |
ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAGCCCAACAAGATTCACCCCAAGATCTATCTAATGAAGAAGC
AACAGAAGCCAATCATTTTGAAGATCTTTTAAAAGAATCCACAGAAAGCTCAGACAATCATCTTGACAACCCCACAGAAA
CTAAAACCCATTTTGATGAAGACAAGCTAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCT
AGCAATGGCAGTCTAGCAGACAAGTTATTCAAGAAAGCCAGAAAATTAGTTGATGATAAAAGACCTTTCACTCAGCAAAA
GAGTTTAGATGAAGAAACCCAAAAACTGAACGAAGAAGACGATCAAGAAAATAATGAGCATCAAGAAGAAACTCAAACGG
ACTTGATTGATGATGAAACTTCTGAAAAAACCCAACAAGATTCACCCCAAGATCTATCTAATGAAGAAGCAACAGAAGCC
AATCATTTTGAAGATCTTTTAAAAGAATCCACAGAAAGTTCAGATAATCATCTTGACAACCCCACAGAAAGCTCAGACAA
TCATCTTGACAACCCCACAGAAACTAAAACCCAAGAAACTAAAACCCATTTTGATGAAGACAAGCCAGAAGAAATAACTG
ACGACTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGCGGCATTGTAGTCGCTGTTCTTATC
GTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTTGTACCTTTGGAAGATAAAAGCTCTCGTTTTAGCAAAGACAG
GAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAGAACGGAATGAAAAAGGCAATA
TGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTGAATATTGCAGAAATTGAGGAC
AAAAACCCATTGAGAGCCTTTTATGAATGTATTAGTAATGGTGGCAACTATGAAGAATGTTTGAAGCTTATCAAAGACAA
AAAACTTCAAGATCAGATGAAAAAGACTCTAGAGGCTTATAATGACTGCATCAAAAATGCCAAAACTGAAGAAGAAAGGA
TCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAAAAAGTTCAAGTGGCTCTAGAT
TGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCCTAAAACTCATAAATGACCCTGAGATTAGAGAGAAATT
CCGTAAGGAATTAGAGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACGCCAAAACAGAAGCTGAGAAAA
ACGAATGCTTGAAAGGCTTGTCTAAAGAAGCCATAGAAAGATTGAAACAACAAGCGCTAGATTGTTTGAAAAACGCTAAA
ACCGATGAAGAACGGAAAGAGTGCTTAAAAAATATTCCCCAAGACTTGCAAAAAGAACTACTAGCTGATATGAGCGTTAA
GGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGA
AAAAACTATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCTTGAAAAAT
CTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGCATCTCAAGCCAAAAC
TGAAGCTGAAAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCG
TTAAGGCTTATTTGGATTGCGTATCTCAGGCCAAAACTGAAGCTGAAAAAAAAGAATGCGAGAAATTGCTCACACCTGAA
GCGAAAAAAAAGTTAGAAGAAGCCAAAAAGAGCGTTAGAGCTTATTTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGA
AAGAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACG
CTAAAACCGATGAAGAACGGAAAGAGTGCTTGAAAGATCTCCCTAAAGACTTACAGAAAAAGGTTTTAGCCAAAGAGAGT
GTTAGGGTTTATTTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGA
AGCGAGAAAGCTATTAGAAGAAGCTAAGAAGAGCGTTAAGGCTTACAAAGACTGCGTTTTAAGAGCTAGGAATGAAAAAG
AGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGGAAACTATTAGAAGAATCTAAAAAAAGCGTTAAGGCTTAT
TTGGATTGCGTATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAGCT
ATTAGAAGAAGCTAAAGAGAGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAAT
GCGAGAAATTACTCACGCCTGAAGCGAGGAAACTATTAGAAGAATCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTA
TCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAGCTATTAGAAGAAGC
TAAAGAGAGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTAC
TCACGCCTGAAGCGAAAAAACTATTAGAGAATCAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAA
AGGTGTGTCAAAGATCTCCCTAAAGACTTACAGAAAAAGGTTTTAGCCAAAGAGAGTGTTAGGGTTTATTTGGATTGCGT
ATCAAAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAGCTATTAGAAGAAG
CTAAAGAGAGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTA
CTCACCCCTGAAGCTAGGAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTTAAGGCTTATTTAGACTGCGTTTCAAGAGC
TAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAGGAAACTTTTAGAGAATCAAGCGCTAG
ATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTT
TTAGCTAAAGAGAGCGTTAAGGCTTATTTAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAA
GTTGCTCACGCCTGAAGCGAGAAAACTATTAGAAGAATCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATCAAAAG
CCAAAAACGAAGCTGAAAAAAAAGAATGCGAGAAATTGCTCACACCTGAAGCGAGAAAGCTATTAGAAGAAGCTAAAGAG
AGTGTTAAGGCTTACAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAACTACTCACCCC
TGAAGCGAGGAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTTAAGGCTTATTTAGACTGTGTATCAAGAGCTAGGAATG
AAAAAGAGAAACAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGGAAATTTTTAGAGAAACAGCGCCAACAAAAAGAT
AAAGCGATAAAGGATTGCTTGAAAAACGCCGATCCTAACGACAGAGCGGCTATCATGAAGTGTTTGGATGGTTTGAGCGA
TGAAGAGAAGCTCAAATACCTGCAAGAAGCCAGAGAAAAGGCTGTCTTGGATTGTTTGAAAACGGCTAGGACCGATGAAG
AAAAAAGGAAATGCCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAAGGCACAGAACAAACAAAATCAA
TTGAGTAAAACAGAAAGGTTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGATCAAGAAGCCATAGA
GCAATGTTTAGAGGGATTGAGCGATAGCGAAAGGGCGCTAATTCTAGGAATCAAACGACAAGCTGATGAAGTGGATCGGA
TTTATAGCGATCTAAGAAGCCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCATTGTTACCAATGGATTTTAAA
AATGGTGGCGATATTGCTACTATTAACGCCACTAATGTTGATGCGGACAAAATAGCTAGCGATAATCCTATTTATGCTTC
CATAGAGCCTGATATTACTAAGCAATACGAAACAGAGAAAACCATTAAGGATAAGAGTTTAGAAGCTAAATTAGCTAAGG
CTTTAGGTGGCGATAAGAAAGATGACGATAAAGAAAAAGGTAAAAAACCCACAGCAGAAACTAAAGCAGAAAGCAATAAG
ATAGACAAAGATGTCGCAGAAACTGCCAAAAATATCAGCGAAATCGCTCTTAAGAACAAAAAAGAAAAGAGTGGGGATTT
TGTAGATGAAAATGGTAATCCCATTGATGATAAAAAGAAAGAAGAAAAACAAGATGAAACAAGCCCTGTCAAACAGGCCT
TTATAGGCAAGAGTGATCCCACATTTGTTTTAGCACAATACACTCCCATTGAAATCACTCTGACTTCTAAAGTAGATGCC
ACTCTCACGGGTATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATCTTATTAGACAAAGG
CACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACGCCTATTATGACTCGTTTAATGATAGTCTTTACTAAAG
CTATTACGCCTGATGGGGTGATTATACCTCTAGCAAACGCTCAAGCAGCAGGCATGCTGGGTGAAGCAGGGGTAGATGGC
TATGTGAATAATCACTTCATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTCTTGCAAACTGCGCC
TATCATAGCCCTAGATAAACTCATAGGTCTTGGCAAAGGCAGAAGTGAAAGGACACCTGAATTTAATTACGCTTTGGGTC
AAGCTATCAATGGCAGTATGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGGGCAACTGATGAATATCCCCCCAAGT
TTTTACAAAAATGAGGGCGATAGCATTAAGATTCTCACCATGGACGATATTGATTTTAGTGGCGTGTATGATGTTAAAAT
TACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACCAAAACTTTGTCTAGAGAACATGAAGAAATCACCACAA
GCCCCAAAGGTGGCAATTGA
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| Protein sequence : | |
MNEENDKLETSKKAQQDSPQDLSNEEATEANHFEDLLKESTESSDNHLDNPTETKTHFDEDKLEETQTQMDSGGNETSES
SNGSLADKLFKKARKLVDDKRPFTQQKSLDEETQKLNEEDDQENNEHQEETQTDLIDDETSEKTQQDSPQDLSNEEATEA
NHFEDLLKESTESSDNHLDNPTESSDNHLDNPTETKTQETKTHFDEDKPEEITDDSNDQEIIKGSKKKYIIGGIVVAVLI
VIILFSRSIFHYFVPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIED
KNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALD
CLKNAKTDEERKECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAK
TDEERKECLKNIPQDLQKELLADMSVKAYKDCVSRARNEKEKQECEKLLTPEAKKLLENQALDCLKNAKTDEERKECLKN
LPKDLQSDILAKESLKAYKDCASQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPE
AKKKLEEAKKSVRAYLDCVSKAKNEAERKECEKLLTPEAKKLLENQALDCLKNAKTDEERKECLKDLPKDLQKKVLAKES
VRVYLDCVSKAKNEAERKECEKLLTPEARKLLEEAKKSVKAYKDCVLRARNEKEKQECEKLLTPEARKLLEESKKSVKAY
LDCVSKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKQECEKLLTPEARKLLEESKKSVKAYLDCV
SKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKQECEKLLTPEAKKLLENQALDCLKNAKTEAEKK
RCVKDLPKDLQKKVLAKESVRVYLDCVSKAKNEAERKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKQECEKL
LTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKLLENQALDCLKNAKTEAEKKRCVKDLPKDLQKKV
LAKESVKAYLDCVSRARNEKEKKECEKLLTPEARKLLEESKKSVKAYLDCVSKAKNEAEKKECEKLLTPEARKLLEEAKE
SVKAYKDCVSRARNEKEKQECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLEKQRQQKD
KAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKKAQNKQNQ
LSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDRIYSDLRSRKTFDNMAAKGYPLLPMDFK
NGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKSLEAKLAKALGGDKKDDDKEKGKKPTAETKAESNK
IDKDVAETAKNISEIALKNKKEKSGDFVDENGNPIDDKKKEEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDA
TLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDG
YVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPS
FYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN
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