PAI Gene Information


Name : escC
Accession : CAI43881.1
PAI name : LEE
PAI accession : AJ303141
Strain : Escherichia coli 042
Virulence or Resistance: Virulence
Product : EscC protein
Function : -
Note : -
Homologs in the searched genomes :   82 hits    ( 82 protein-level )  
Publication :
    -Jores,J., "Direct Submission", Submitted (02-JAN-2001) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY REMARK revised by [3].

    -Jores,J., "Direct Submission", Submitted (09-SEP-2004) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY.

    -Jores,J., Rumer,L., Kiessling,S., Kaper,J.B. and Wieler,L.H., "A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2", FEMS Microbiol. Lett. 204 (1), 75-79 (2001) PUBMED 11682182.

    -Jores,J., Wagner,S., Rumer,L., Eichberg,J., Laturnus,C., Kirsch,P., Schierack,P., Tschape,H. and Wieler,L.H., "Description of a 111-kb pathogenicity island (PAI) encoding various virulence features in the enterohemorrhagic E. coli (EHEC) strain RW1374 (O103:H2) and detection of a similar PAI in other EHEC strains of serotype 0103:H2", Int. J. Med. Microbiol. 294 (7), 417-425 (2005) PUBMED 15715170.

    -Rumer,L., Jores,J., Kirsch,P., Cavignac,Y., Zehmke,K. and Wieler,L.H., "Dissemination of pheU- and pheV-located genomic islands among enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli and their possible role in the horizontal transfer of the locus of enterocyte effacement (LEE)", Int. J. Med. Microbiol. 292 (7-8), 463-475 (2003) PUBMED 12635929.


DNA sequence : 
ATGAAAAAAATAAGTTTTTTTATTTTTACAGCACTATTTTGCTGCAGTGCTCAGGCTGCCCCGTCCTCTCTGGAAAAAAG
ATTAGGCAAGAACGAGTATTTTATTATTACAAAAAGCTCTCCGGTACGTGCAATCCTCAATGATTTTGCCGCTAATTATA
GCATCCCTGTTTTCATCAGTAATTCTGTGAATGATGATTTCTCTGGTGAAATAAAAAATGAAAAACCAATGAAAGTACTG
GAAAAACTGTCCAGGCTCTATCATCTCACATGGTATTATGATGAGAACATTTTGTATATTTATAAAACAAATGAAATATC
AAGAAGCATAATTACGCCAACATATCTGGATATTGACTCACTGTTAAAATATCTGCGTGATACAATCTCAGTAAATAAAA
ACTCCTGTAACGTGAGAAAAATCACAACATTTAACTCGATTGAAGTTCGTGGCGTTCCTGAATGCATAAAATACATTACA
TCTTTATCTGAAAGTCTTGATAAAGAAGCACAGTCTAAAGCAAAAAATAAAGATGTCGTTAGAGTATTTAAATTAAACTA
TGCATCAGCGACAGATATAACGTATAAATACCGCGACCAAAATGTTGTCGTGCCTGGCGTCGTCTCCATCCTGAAGACGA
TGGCAAGTAATGGCTCACTTCCCAGCACAGGCAAAGGTGCTGTAGAAAGAAACGGCAACCTGTTTGATAACAGTGTAAAG
ATTTCCGCAGATCCACGTCTTAATGCAGTTGTTGTAAAAGATCGTGAAATAACTATGGACATATATCGGCAATTAATTTC
TGAGCTTGATATTGAGCAAAGGCAAATTGAGATTTCTGTTTCAATTATTGATGTTGATGCAAATGATCTTCAGCAACTGG
GAGTAAACTGGTCCGGTACATTAAATGCAGGGCAAGGTTCTATTGCCTTTAACAGCTCAACGGCGCAAGCTAATCTCAGT
TCTTCTGTGATAAGCAACGCCAATAATTTCATGATCAGAGTGAATGCGTTACAACAGAACTCGAAAGCAAAAATACTCTC
TCAGCCATCAATTATAACCTTAAATAATATGCAGGCGATTCTTGATAAAAACGTAACGTTTTATACAAAAGTTTCCGGAG
AAAAGGTGGCATCTCTGGAAAGTATTACCAGCGGAACATTACTGAGAGTGACACCACGTATACTTGATGACAACTCGAAT
AGTCTTACCGGAAAACGTCGGGAACGAGTTCGTTTGTTACTTGATATTCAGGATGGCAATCAATCGACTAACCAAAGTAA
TGCTCAGGATGCCAGCAGCATCTTACCTGAAGTACAAAATTCAGAAATGACAACAGAAGCGACATTAAGCGCTGGAGAAA
GTCTGCTGCTTGGCGGATTTATCCAGGATAAAGAGAGTTCAAGTAAAGATGGTATACCGTTGTTAAGTGATATTCCTGTT
ATTGGTAACTTATTCTCCAGTACAACAAAACAAAAACACAGCGTTGTTCGACTCTTTTTGATTAAAGCGACCCCGATAAA
ATCAGCATCTAGCGAATAA

Protein sequence : 
MKKISFFIFTALFCCSAQAAPSSLEKRLGKNEYFIITKSSPVRAILNDFAANYSIPVFISNSVNDDFSGEIKNEKPMKVL
EKLSRLYHLTWYYDENILYIYKTNEISRSIITPTYLDIDSLLKYLRDTISVNKNSCNVRKITTFNSIEVRGVPECIKYIT
SLSESLDKEAQSKAKNKDVVRVFKLNYASATDITYKYRDQNVVVPGVVSILKTMASNGSLPSTGKGAVERNGNLFDNSVK
ISADPRLNAVVVKDREITMDIYRQLISELDIEQRQIEISVSIIDVDANDLQQLGVNWSGTLNAGQGSIAFNSSTAQANLS
SSVISNANNFMIRVNALQQNSKAKILSQPSIITLNNMQAILDKNVTFYTKVSGEKVASLESITSGTLLRVTPRILDDNSN
SLTGKRRERVRLLLDIQDGNQSTNQSNAQDASSILPEVQNSEMTTEATLSAGESLLLGGFIQDKESSSKDGIPLLSDIPV
IGNLFSSTTKQKHSVVRLFLIKATPIKSASSE