PAI Gene Information


Name : escN
Accession : CAI43874.1
PAI name : LEE
PAI accession : AJ303141
Strain : Escherichia coli 042
Virulence or Resistance: Virulence
Product : EscN protein
Function : -
Note : -
Homologs in the searched genomes :   1605 hits    ( 1605 protein-level )  
Publication :
    -Jores,J., "Direct Submission", Submitted (02-JAN-2001) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY REMARK revised by [3].

    -Jores,J., "Direct Submission", Submitted (09-SEP-2004) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY.

    -Jores,J., Rumer,L., Kiessling,S., Kaper,J.B. and Wieler,L.H., "A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2", FEMS Microbiol. Lett. 204 (1), 75-79 (2001) PUBMED 11682182.

    -Jores,J., Wagner,S., Rumer,L., Eichberg,J., Laturnus,C., Kirsch,P., Schierack,P., Tschape,H. and Wieler,L.H., "Description of a 111-kb pathogenicity island (PAI) encoding various virulence features in the enterohemorrhagic E. coli (EHEC) strain RW1374 (O103:H2) and detection of a similar PAI in other EHEC strains of serotype 0103:H2", Int. J. Med. Microbiol. 294 (7), 417-425 (2005) PUBMED 15715170.

    -Rumer,L., Jores,J., Kirsch,P., Cavignac,Y., Zehmke,K. and Wieler,L.H., "Dissemination of pheU- and pheV-located genomic islands among enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli and their possible role in the horizontal transfer of the locus of enterocyte effacement (LEE)", Int. J. Med. Microbiol. 292 (7-8), 463-475 (2003) PUBMED 12635929.


DNA sequence : 
ATGATTTCAGAGCATGATTTTGTATTGGAAAGATACCCACGTATCCAGAGAGTGCTCAATAGCACTGTGCCGACATTATC
ATTAAATTCGTCTACCAGATATGAAGGCAAGATTACCAATATCGGCGGGACGATTATCAAGGCGCGTTTACCAAAAGCGC
GTATTGGCGCCTTTTACAGGATAGAACCCAGTCAACGTTTAGCTGAGGTGATCGCTATTGATGAAGATGAGGTTTTCCTG
CTGCCTTTTGAGCATATTTCCGGCATGTATTGTGGCCAGTGGCTAAGTTATCAGGGGGATGAGTTCAAGATTCGTGTTGG
GGACGAACTCCTTGGGCGACTGGTTGATGGTATAGGCAGACCAATGGGGAGCAATATTACTGCACCTTATCTTCCGTTTG
AACGCAGTTTGTATGCTGAACCCCCCGATCCTTTATTAAGGCAGGTTATTGATCAGCCATTTACGCTTGGCGTCAGGGCA
ATAGATGGTTTACTTACTTGCGGTATTGGGCAACGTATCGGTATTTTCGCGGGGTCCGGCGTTGGTAAAAGTACGCTTTT
GGGAATGATTTGTAATGGCGCATCCGCGGATATTATTGTCCTTGCCCTTATCGGCGAGCGTGGTCGCGAAGTAAATGAAT
TCCTCGCGCTTTTACCTCAATCCACGCTTTCTAAATGTGTACTGGTCGTCACAACGTCAGACCGTCCCGCGCTGGAAAGA
ATGAAGGCCGCATTTACGGCGACAACCATTGCAGAGTTCTTCCGGGATCAGGGCAAAAATGTATTATTAATGATGGATTC
CGTAACTCGTTATGCCCGAGCCGCGCGTGATGTTGGGCTTGCATCGGGAGAGCCTGATGTAAGGGGGGGATTCCCTCCGA
GTGTTTTTTCCTCGTTACCCAAATTATTAGAGCGTGCGGGGCCTGCGCCAAAAGGCTCAATAACCGCGATTTATACGGTG
TTGTTAGAAAGCGATAATGTTAATGATCCCATTGGTGATGAAGTCCGCTCTATTCTTGATGGGCACATTGTGCTTACCCG
AGAACTTGCAGAGGAAAATCATTTTCCTGCAATTGATATTGGTTTAAGCGCCAGTCGTGTTATGCATAATGTTGTTACAT
CGGAGCATTTGCGTGCGGCGGCAGAATGCAAAAAGCTTATCGCAACCTATAAAAATATTGAGCTGCTTATTCGTATTGGT
GAGTACACGATGGGGCAAGATCCTGAAGCGGATAAGGCAATAAAAAACAGGAAAGCAATTCAGAGCTTTATACAACAAAG
CACCAAAGATATCAGTAGTTACGAAAAAACGATTGAAAGCCTATTCAAAGTGGTTGCCTGA

Protein sequence : 
MISEHDFVLERYPRIQRVLNSTVPTLSLNSSTRYEGKITNIGGTIIKARLPKARIGAFYRIEPSQRLAEVIAIDEDEVFL
LPFEHISGMYCGQWLSYQGDEFKIRVGDELLGRLVDGIGRPMGSNITAPYLPFERSLYAEPPDPLLRQVIDQPFTLGVRA
IDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALER
MKAAFTATTIAEFFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTV
LLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYKNIELLIRIG
EYTMGQDPEADKAIKNRKAIQSFIQQSTKDISSYEKTIESLFKVVA