PAI Gene Information


Name : unnamed
Accession : CAI43843.1
PAI name : LEE
PAI accession : AJ303141
Strain : Escherichia coli 042
Virulence or Resistance: Not determined
Product : hypothetical protein
Function : -
Note : orf40
Homologs in the searched genomes :   319 hits    ( 319 protein-level )  
Publication :
    -Jores,J., "Direct Submission", Submitted (02-JAN-2001) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY REMARK revised by [3].

    -Jores,J., "Direct Submission", Submitted (09-SEP-2004) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY.

    -Jores,J., Rumer,L., Kiessling,S., Kaper,J.B. and Wieler,L.H., "A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2", FEMS Microbiol. Lett. 204 (1), 75-79 (2001) PUBMED 11682182.

    -Jores,J., Wagner,S., Rumer,L., Eichberg,J., Laturnus,C., Kirsch,P., Schierack,P., Tschape,H. and Wieler,L.H., "Description of a 111-kb pathogenicity island (PAI) encoding various virulence features in the enterohemorrhagic E. coli (EHEC) strain RW1374 (O103:H2) and detection of a similar PAI in other EHEC strains of serotype 0103:H2", Int. J. Med. Microbiol. 294 (7), 417-425 (2005) PUBMED 15715170.

    -Rumer,L., Jores,J., Kirsch,P., Cavignac,Y., Zehmke,K. and Wieler,L.H., "Dissemination of pheU- and pheV-located genomic islands among enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli and their possible role in the horizontal transfer of the locus of enterocyte effacement (LEE)", Int. J. Med. Microbiol. 292 (7-8), 463-475 (2003) PUBMED 12635929.


DNA sequence :
ATGCGACTAGCCAGTCGTTTTGGTTATGCGAACCAGATACGCCGTGACCGTCCGCTGACACACGAAGAACTGATGCACTA
TGTGCCGGGGATTTTCGGGGAAGATAAACACACGTCCCGAAGCCAGAACTATACGTACATCCCCACCATCACCGTACTGG
AAAGCCTGCAGCGGGAAGGCTTTCAGCCATTCTTCGCCTGCCAGACCCGTGTGCGCGACCCGGGCCGCCGGGGATACACA
AAACACATGCTGCGTCTGCGGCGGGCCGGAGAGATAAACGGAGAACATGTCCCTGAAATTATTCTGCTCAACTCTCATGA
CGGTACCTCCAGCTACCAGATGCTGCCGGGTTACTTCAGGTTCGTCTGCCAGAACGGATGCGTCTGTGGTCAGTCTCTGG
GGGAAGTGCGTGTTCCGCACCGGGGAAATGTGGTGGACAGAGTCATTGAAGGGGCTTACGAGGTGGTGGGGGTTTTTGAC
CGGATTGAGGAAAAGCGTGATGCCATGCAGTCGCTGATTCTGCCGCCACCGGCACGCCAGGCGCTGGCACAGGCGGCACT
GACTTACCGTTATGGTGACGAACATCAGCCCGTCACCACCGCCGACATTCTGACGCCACGACGCCGGGAGGATTACGGTA
AGGACCTGTGGAGTGCTTATCAGACCATTCAGGAGAATATGCTGAAAGGCGGAATTTCAGGTCGCAGCGCTAAAGGAAAA
CGTATCCATACCCGTGCCATTCACAGCATTGACACTGACATTAAGCTCAACCGCGCATTGTGGGTGATGGCGGAAACGCT
GCTGGAGAGCCTGCGCTGA

Protein sequence :
MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNYTYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYT
KHMLRLRRAGEINGEHVPEIILLNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWSAYQTIQENMLKGGISGRSAKGK
RIHTRAIHSIDTDIKLNRALWVMAETLLESLR