PAI Gene Information


Name : unnamed
Accession : CAI43808.1
PAI name : LEE
PAI accession : AJ303141
Strain : Escherichia coli 042
Virulence or Resistance: Not determined
Product : putative transposase
Function : -
Note : orf5
Homologs in the searched genomes :   10 hits    ( 5 protein-level,   5 DNA-level )  
Publication :
    -Jores,J., "Direct Submission", Submitted (02-JAN-2001) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY REMARK revised by [3].

    -Jores,J., "Direct Submission", Submitted (09-SEP-2004) Jores J., Institut fuer Mikrobiologie und Tierseuchen, Freie Universitaet Berlin, Philippstrasse 13, 10115 Berlin, Berlin, 10115, GERMANY.

    -Jores,J., Rumer,L., Kiessling,S., Kaper,J.B. and Wieler,L.H., "A novel locus of enterocyte effacement (LEE) pathogenicity island inserted at pheV in bovine Shiga toxin-producing Escherichia coli strain O103:H2", FEMS Microbiol. Lett. 204 (1), 75-79 (2001) PUBMED 11682182.

    -Jores,J., Wagner,S., Rumer,L., Eichberg,J., Laturnus,C., Kirsch,P., Schierack,P., Tschape,H. and Wieler,L.H., "Description of a 111-kb pathogenicity island (PAI) encoding various virulence features in the enterohemorrhagic E. coli (EHEC) strain RW1374 (O103:H2) and detection of a similar PAI in other EHEC strains of serotype 0103:H2", Int. J. Med. Microbiol. 294 (7), 417-425 (2005) PUBMED 15715170.

    -Rumer,L., Jores,J., Kirsch,P., Cavignac,Y., Zehmke,K. and Wieler,L.H., "Dissemination of pheU- and pheV-located genomic islands among enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli and their possible role in the horizontal transfer of the locus of enterocyte effacement (LEE)", Int. J. Med. Microbiol. 292 (7-8), 463-475 (2003) PUBMED 12635929.


DNA sequence : 
ATGGGCAACTCAATGCACTCTCTTAAGACACTTCTACAGTTACCTTGCGGATGGCGATGCAGTCGACAAATTATTAGCTC
TGACGGTATAACCCTCCATCTCCACGGAAAACGCAAAAAAGCACAATGTCCTGAATGCTTTAAGCGTAGCGACTCTGTTC
ATAGTTGTCGTCGGCGCCGGATACAGCATCTACCCTGCTCAGGACATACGCTATGGCTTGTATTTTCCGTCCGCCACTGG
TACTGCCGTAACCCGGCTTGTTCACGTAAAATTTTTGCCGGGTCGCTTGCTCCCTTCGCCGGTTCACACCAACAGTCTTC
ACAGGCGTTACAAAATTTACAACGTCAACTGGGATTAATCGCCGGAGGTGAGGCCGGGAAACGGGCAGCAACGGCAGTGG
GGCTCCGTTGCAGTGCTGATACTCTCCTTCGCAGGGTTATCAATACCCCGGAGACGAAACAGTCAGGCGCGCCTCATGTC
GGTATTGATGAGTGGGCGTGGCATCGGGGCCACCGTTACGGTACGTTAATCGTCAATCTTGATACTCACCGTCCCCTCGT
CCTGCTTCCCGGCCGTGATCAGCGTACGCTGGCGACCTGGTTCAGAAAATATCCGGAAATACAGGTTGTCTCGCGTGATC
GCAGTGGAGTCTATGCGACAGCAGCACGTGAAGGTGCACCTCAGGCCAGACAGGTGGCCGATCGATGGCATCTGCTAAAA
AATATTGGCGATGCGCTTGAACGAATGATGTACAGACATATACCTCTGATACGTCTTGTTGCCAGTGAGTTGTCACCAAA
GAAATCACCTGATCCAGAACCATCTGTGCCTGCAGCATCGCTCCGTCGTCCGGAACGCCTAAAACAACAAACCCGCAAAA
AACGGCATCAGCGTTGGACAGAGGTTATGGCCCTGCATAACAAGGAATGTAGTTTCAGGGAAATATCCCGTATTACAGGC
CTGTCGCGTGTGACAGTCAGTCGCTGGGTGCGTTCAGGAACATTCCCTGAAATGTCAACCCGACCTCCAAAGCGAGGGCT
TCTGGACCCATGGAGGGAGTGGTTAAAAGAGCAACGAGAAAGTAGTAATTATAACGCCAGCCGGATATGGCGGGAAATGG
TGGCCCGGGGATTTACAGGCAGTGAAACCATCGTCAGGGATGCGGTTGCCAAATGGCGTAAAGGCTGGAACCCACCGGTT
ACTACTGCCGTCAGACTTCCTTCAGTGTCCCGGGTAAGCCGCTGGTTGATGCCCTGGAGAATAACCAGGGATGAAGAAAA
TTATGCTTCCCGATTTATTAGTCTGATGTGTGAAAAAGAACCTGAGCTGAAAATAGCGCAGCAACTGGCACTCGAGTTCT
ACCGTATTCTGAAAACCCAAAATAAATCACAGCTAAGCAGTTGGTTCAATCGAGTCCACGAAAGCGGTTCAGCAGAATTT
CGGCGCGTGGCGGCGGGGATGGAAGCTGATGCTGCAGCTATATGTGAGGCAATCAGTAGTCGCTGGAGTAATGGTGTTGT
CGAAGGTCATGTAAATCGCCTGAAGATGCTGAAACGCCAGATGTATGGTCGAGCAGGATTTGAACTACTCAGGCAGAGGG
TAATGAGTCCACTGGCATGA

Protein sequence : 
MGNSMHSLKTLLQLPCGWRCSRQIISSDGITLHLHGKRKKAQCPECFKRSDSVHSCRRRRIQHLPCSGHTLWLVFSVRHW
YCRNPACSRKIFAGSLAPFAGSHQQSSQALQNLQRQLGLIAGGEAGKRAATAVGLRCSADTLLRRVINTPETKQSGAPHV
GIDEWAWHRGHRYGTLIVNLDTHRPLVLLPGRDQRTLATWFRKYPEIQVVSRDRSGVYATAAREGAPQARQVADRWHLLK
NIGDALERMMYRHIPLIRLVASELSPKKSPDPEPSVPAASLRRPERLKQQTRKKRHQRWTEVMALHNKECSFREISRITG
LSRVTVSRWVRSGTFPEMSTRPPKRGLLDPWREWLKEQRESSNYNASRIWREMVARGFTGSETIVRDAVAKWRKGWNPPV
TTAVRLPSVSRVSRWLMPWRITRDEENYASRFISLMCEKEPELKIAQQLALEFYRILKTQNKSQLSSWFNRVHESGSAEF
RRVAAGMEADAAAICEAISSRWSNGVVEGHVNRLKMLKRQMYGRAGFELLRQRVMSPLA