PAI Gene Information


Name : aadA1
Accession : CAD92142.1
PAI name : Not named
PAI accession : Y18050
Strain : Pseudomonas aeruginosa B136-33
Virulence or Resistance: Resistance
Product : aminoglycoside adenyltransferase
Function : -
Note : -
Homologs in the searched genomes :   130 hits    ( 130 protein-level )  
Publication :
    -Lauretti,L., Riccio,M.L., Mazzariol,A., Cornaglia,G., Amicosante,G., Fontana,R. and Rossolini,G.M., "Cloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate", Antimicrob. Agents Chemother. 43 (7), 1584-1590 (1999) PUBMED 10390207.

    -Rossolini,G.M., "Direct Submission", Submitted (04-SEP-1998) G.M. Rossolini, Dip. Biologia Moleculare-Sez., Microbiologia,, Univ. di Siena, via Laterina N.8, I- 53100 Siena, ITALY REMARK revised by [3].

    -Rossolini,G.M., "Direct Submission", Submitted (01-MAY-2003) G.M. Rossolini, Dip. Biologia Moleculare-Sez., Microbiologia,, Univ. di Siena, via Laterina N.8, I- 53100 Siena, ITALY.


DNA sequence :
ATGAGGGAAGCGGTGATCGCCGAAGTATCGACTCAACTATCAGAGGTAGTTGGCGTCATCGAGCGCCATCTCGAACCGAC
GTTGCTGGCCGTACATTTGTACGGCTCCGCAGTGGATGGCGGCCTGAAGCCACACAGTGATATTGATTTGCTGGTTACGG
TGACCGTAAGGCTTGATGAAACAACGCGGCGAGCTTTGATCAACGACCTTTTGGAAACTTCGGCTTCCCCTGGAGAGAGC
GAGATTCTCCGCGCTGTAGAAGTCACCATTGTTGTGCACGACGACATCATTCCGTGGCGTTATCCAGCTAAGCGCGAACT
GCAATTTGGAGAATGGCAGCGCAATGACATTCTTGCAGGTATCTTCGAGCCAGCCACGATCGACATTGATCTGGCTATCT
TGCTGACAAAAGCAAGAGAACATAGCGTTGCCTTGGTAGGTCCAGCGGCGGAGGAACTCTTTGATCCGGTTCCTGAACAG
GATCTATTTGAGGCGCTAAATGAAACCTTAACGCTATGGAACTCGCCGCCCGACTGGGCTGGCGATGAGCGAAATGTAGT
GCTTACGTTGTCCCGCATTTGGTACAGCGCAGTAACCGGCAGAATCGCGCCGAAGGATGTCGCTGCCGACTGGGCAATGG
AGCGCCTGCCGGCCCAGTATCAGCCCGTCATACTTGAAGCTAGACAGGCTTATCTTGGACAAGAAGAAGATCGCTTGGCC
TCGCGCGCAGATCAGTTGGAAGAATTTGTTCACTACGTGAAAGGCGAGATCACCAAGGTAGTCGGCAAATAA

Protein sequence :
MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDIDLLVTVTVRLDETTRRALINDLLETSASPGES
EILRAVEVTIVVHDDIIPWRYPAKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
DLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGRIAPKDVAADWAMERLPAQYQPVILEARQAYLGQEEDRLA
SRADQLEEFVHYVKGEITKVVGK