PAI Gene Information


Name : cagE
Accession : BAD51906.1
PAI name : cag PAI
PAI accession : AB191077
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein E
Function : -
Note : -
Homologs in the searched genomes :   43 hits    ( 43 protein-level )  
Publication :
    -Yamazaki,S., Yamakawa,A. and Azuma,T., "Direct Submission", Submitted (24-SEP-2004) Takeshi Azuma, University of Fukui, Faculty of Medical Sciences, Second Department of Internal Medicine; Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:81-776-61-8351, Fax:81-776-61-8110).

    -Yamazaki,S., Yamakawa,A., Okuda,T., Ohtani,M., Suto,H., Ito,Y., Yamazaki,Y., Keida,Y., Higashi,H., Hatakeyama,M. and Azuma,T., "Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan", J. Clin. Microbiol. 43 (8), 3906-3916 (2005) PUBMED 16081930.


DNA sequence :
GTGTTTGTGGCGAGCAAGCAAGCCGATGAACAAAAAAAGCTAATCATAGAGCAAGAGGTTCAAAAGCGGCAGTTTCAAAA
AATAGAAGAGCTTAAAGCAGACATGCAAAAAGGTGTCAATCCCTTTTTTAAAGTCTTGTTTGATGGGGGGAATAGGTTGT
TTGGTTTCCCTGAAACTTTTATTTATTCCTCTATATTTATATTATTCGTAACAATTGTCTTATCTGTTATTCTTTTTCAA
GCCTATGAACCTGTTTTGATTGTGGCGATTGTTATTGTGCTTGTAGCTCTTGGATTCAAGAAAGACTATAGGCTTTATCA
AAGAATGGAGCGAGCGATGAAATTTAAAAAACCTTTTTTGTTTAAGGGCGTGAAAAACAAAGCATTCATGAGCATTTTTT
CCATGAAGCCTAGTAAAGAAATGGCTAATGACATCCACTTAAATCCAAACAGAGAAGACAGACTTGTGAGCGCTGCAAAC
TCCTATCTAGCGAATAACTATGAATGTTTTTTAGATGATGGGGTGATCCTTACTAACAACTATTCTCTTTTAGGCACAAT
CAAATTGGGGGGCATTGATTTTTTAACCACTTCCAAAAAAGATCTCATAGAGTTACACGCTTCTATTTATAGCGTTTTTA
GGAATTTTGTTACCCCTGAATTCAAATTTTATTTCCACACTGTTAAAAAGAAAATCGTTATTGATGAAACCAATAGGGAC
TATAGTCTTGCTTTTTCTAATGATTTTATGCGAGCCTATAATGAGAAGCAAAAAAGAGAAAGTTTTTATGATATTAGTTT
TTTTCTGACCATAGAGCAAGATTTATTAGACACTCTCAATGAACCTGTTATGAATAAAAAGCATTTTGCAGACAATAATT
TTGAAGAGTTTCAAAGGATTATTAGAGCCAAGCTTGAAAACTTCAAGGATAGGATAGAGCTCATAGAAGAGCTATTGAGT
AAATACCACCCCACTAGATTGAAAGAATACACTAAAGATGGCGTTGTTTATTCCAAACAATGCGAGTTTTATAATTTTCT
TGTGGGAATGAATGAAGCCCCTTTTATTTGCAACAGAAAAGACTTGTATCTCAAGGAAAAAATGCATGGTGGGGTGAAAG
AAGTTTATTTTGCCAATAAGCATGGAAAAATCTTAAATGACGATTTGAGTGAAAAATATTTTAGCACTATTGAGATTAGT
GAATACGCCCCTAAATCACAGAGCGATTTGTTTGACAAGATCAACGCTCTAGACAGCGAATTCATCTTTATGCATGCTTA
TTCGCCTAAAAACTCACAAGTTTTAAAGGACAAACTAGCTTTCACCTCTAGAAGGATTATTATCAGTGGGGGTTCTAAAG
AGCAGGGCATGACTTTAGGTTGCTTGAGCGAATTAGTGGGTAATGGTGATATTACGCTAGGCAGTTATGGTAATTCTTTA
GTGCTGTTTGCTGATAGCTTTGAAAAAATGAAACAAAGCGTCAAGGAATGCGTCTCTAGTCTTAACGCTAAAGGTTTTTT
AGCCAACGCAGCGACTTTCTCTATGGAAAATTACTTTTTTGCCAAACATTGCTCTTTTATCACGCTTCCTTTTATTTTTG
ATGTAACTTCTAATAATTTTGCTGATTTTATCGCTATGAGAGCGATGAGTTTTGATGGCAATCAAGAGAATAACGCTTGG
GGTAATAGCGTCATGACGCTAAAAAGCGAGATCAATTCGCCTTTTTATCTGAACTTCCACATGCCTACTGATTTTGGTTC
AGCCTCAGCAGGACACACTTTGATACTTGGATCAACCGGTTCAGGTAAGACAGTGTTTATGTCAATGACTCTAAACGCTA
TGGGACAATTTGCTCACAATTTTCCTGCTAATGTCAGCAAAGACAAACAAAAGCTCACTATGGTCTATATGGACAAGGAC
TATGGGGCTTATGGGAACATTGTTGCAATGGGTGGGGAGTATGTCAAGATTGAGCTAGGGACAGATACAGGATTAAATCC
TTTTGCTTGGGCGGCTTGTGTGCAAAAAACAAATGCAACAATAGAGCAAAAACAAACAGCTATTTCTGTTGTCAAAGAGC
TTGTGAAAAACTTAGCAACCAAAAGCGATGAAAAAGATGAAAATGGCAACAGCATCTCTTTTAGCCTAGCTGATTCTAAT
ACGCTTGCAGCGGCAGTAACCAACCTTATCACAGGAGATATGAACCTAGATTATCCCATCACTCAACTTATTAATGCTTT
CGGGAAAGACCACAATGATCCTAATGGGCTTGTTGCGCGATTAGCGCCTTTTTGCAAATCAACCAATGGTGAATTTCAAT
GGCTTTTTGATAATAAAGCAACAGATCGTTTAGATTTTTCAAAAACGATTATTGGCGTTGATGGGTCAAGTTTCTTAGAC
AATAATGATGTTTCGCCCTTTATTTGTTTTTACCTTTTCGCTCGTATTCAAGAGGCAATGGATGGGCGTAGATTTGTCTT
AGATATTGATGAAGCCTGGAAATATTTAGGCGATCCAAAGGTCGCTTATTTTGTAAGAGACATGCTAAAAACTGCAAGGA
AAAGAAACGCTATTGTTAGACTTGCGACTCAAAGCATCACTGATCTTTTGGCTTGCCCCATTGCTGATACTATTAGAGAA
CAATGCCCTACAAAGATTTTTCTGAGAAACGATGGGGGCAATCTTTCTGATTACCAAAGATTAGCCAATGTTACAGAAAA
AGAATTTGAAATCATCACTAAGGGGTTAGATAGGAAAATTCTCTACAAACAAGATGGAAGCCCTAGCGTTATCGCTAGTT
TTAATTTGAGAGGCATTCCTAAAGAATATTTGAAAATTTTATCCACAGATACTGTATTTGTCAAAGAAATTGACAAGATT
ATCCAAAACCATAGTATCATAAATAAATATCAGGCCTTGAGGCAGATGTATCAACAAATAAAGGAGTATTAA

Protein sequence :
MFVASKQADEQKKLIIEQEVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSIFILFVTIVLSVILFQ
AYEPVLIVAIVIVLVALGFKKDYRLYQRMERAMKFKKPFLFKGVKNKAFMSIFSMKPSKEMANDIHLNPNREDRLVSAAN
SYLANNYECFLDDGVILTNNYSLLGTIKLGGIDFLTTSKKDLIELHASIYSVFRNFVTPEFKFYFHTVKKKIVIDETNRD
YSLAFSNDFMRAYNEKQKRESFYDISFFLTIEQDLLDTLNEPVMNKKHFADNNFEEFQRIIRAKLENFKDRIELIEELLS
KYHPTRLKEYTKDGVVYSKQCEFYNFLVGMNEAPFICNRKDLYLKEKMHGGVKEVYFANKHGKILNDDLSEKYFSTIEIS
EYAPKSQSDLFDKINALDSEFIFMHAYSPKNSQVLKDKLAFTSRRIIISGGSKEQGMTLGCLSELVGNGDITLGSYGNSL
VLFADSFEKMKQSVKECVSSLNAKGFLANAATFSMENYFFAKHCSFITLPFIFDVTSNNFADFIAMRAMSFDGNQENNAW
GNSVMTLKSEINSPFYLNFHMPTDFGSASAGHTLILGSTGSGKTVFMSMTLNAMGQFAHNFPANVSKDKQKLTMVYMDKD
YGAYGNIVAMGGEYVKIELGTDTGLNPFAWAACVQKTNATIEQKQTAISVVKELVKNLATKSDEKDENGNSISFSLADSN
TLAAAVTNLITGDMNLDYPITQLINAFGKDHNDPNGLVARLAPFCKSTNGEFQWLFDNKATDRLDFSKTIIGVDGSSFLD
NNDVSPFICFYLFARIQEAMDGRRFVLDIDEAWKYLGDPKVAYFVRDMLKTARKRNAIVRLATQSITDLLACPIADTIRE
QCPTKIFLRNDGGNLSDYQRLANVTEKEFEIITKGLDRKILYKQDGSPSVIASFNLRGIPKEYLKILSTDTVFVKEIDKI
IQNHSIINKYQALRQMYQQIKEY