PAI Gene Information


Name : cagE
Accession : BAD51901.1
PAI name : cag PAI
PAI accession : AB191072
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein E
Function : -
Note : -
Homologs in the searched genomes :   43 hits    ( 43 protein-level )  
Publication :
    -Yamazaki,S., Yamakawa,A. and Azuma,T., "Direct Submission", Submitted (24-SEP-2004) Takeshi Azuma, University of Fukui, Faculty of Medical Sciences, Second Department of Internal Medicine; Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:81-776-61-8351, Fax:81-776-61-8110).

    -Yamazaki,S., Yamakawa,A., Okuda,T., Ohtani,M., Suto,H., Ito,Y., Yamazaki,Y., Keida,Y., Higashi,H., Hatakeyama,M. and Azuma,T., "Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan", J. Clin. Microbiol. 43 (8), 3906-3916 (2005) PUBMED 16081930.


DNA sequence :
GTGGCAAGCAAGCAAGCTGACGAACAAAAAAAGCTAATCATAGAGCAAGAGGTTCAAAAGCGGCAGTTTCAAAAAATAGA
AGAGCTTAAAGCAGACATGCAAAAAGGTGTCAATCCCTTTTTTAAAGTCTTGTTTGATGGGGGGAATAGGTTGTTTGGTT
TCCCTGAAACTTTTATTTATTCCTCTATATTTATATTGTTTGTAACAATTGTATTGTCTGTTATTCTTTTTCAAGCCTAT
GAACCTGTTTTGATTGTAGCGATTGTTATTGTGCTTGTAGCTCTTGGATTCAAGAAAGACTATAGGCTTTATCAAAGAAT
GGAGCGAGCGATGAAATTTAAAAAACCTTTTTTGTTTAAGGGAGTGAAAAACAAAGCGTTCATGAGCATTTTTTCCATGA
AGCCTAGTAAAGAAATGGCTAATGACATCCACTTAAATCCAAACAGAGAAGACAGACTTGTGAGCGCTGCAAACTCCTAT
CTAGCGAATAACTATGAATGTTTTTTAGATGATGGGGTGATCCTTACTAACAACTATTCTCTTTTAGGCACAATCAAATT
GGGGGGCATTGATTTTTTAACCACTTCCAAAAAAGATCTCATAGAGTTACACGCTTCTATTTATAGCGTTTTTAGGAATT
TTGTTACCCCTGAATTCAAATTTTATTTTCACACTGTTAAAAAGAAAATCGTTATTGATGAAACCAATAGGGACTATAGT
CTTGCTTTTTCTAATGATTTTATGCGAGCCTATAATGAGAAGCAAAAAAGAGAAAGTTTTTATGATATTAGTTTTTTTCT
GACCATAGAACAAGATTTATTAGACACTCTCAATGAACCCGTTATGAATAAAAAGCATTTTGCAGACAATAATTTTGAAG
AGTTTCAAAGGATTATTAGAGCCAAGCTTGAAAACTTCAAAGATAGGATAGAGCTCATAGAAGAGCTATTGAGTAAATAC
CACCCCACTAGATTAAAAGAATACACTAAAGATGGGGTTGTTTATTCCAAACAATGCGAGTTTTACAATTTTCTTGTGGG
AATGAATGAAGCCCCTTTTATTTGCAACAGAAAAGACTTGTATCTCAAGGAAAAAATGCATGGTGGGGTGAAAGAAGTTT
ATTTTGCCAACAAACATGGAAAAATCTTAAATGACGATTTGAGTGAAAAATATTTTAGTGCTATTGAGATTAGTGAATAC
GCCCCCAAATCACAGAGCGATTTGTTTGACAAGATCAACGCTCTAGACAGCGAATTCATCTTTATGCATGCTTATTCGCC
TAAAAACTCACAGGTTTTAAAGGACAAACTAGCTTTCACCTTTAGAAGAATTATTATTAGTGGGGGTTCTAAAGAGCAGG
GCATGACTTTAGGTTGCTTGAGCGAATTAGTGGGTAATGGTGATATTACGCTAGGCAGTTATGGTAATTCTTTAGTGCTG
TTTGCTGATAGTTTTGAAAAAATGAAACAAAGCGTTAAGGAATGCGTCTCTAGTCTTAACGCTAAAGGTTTTTTAGCCAA
CGCAGCGACTTTCTCTATGGAAAATTACTTTTTTGCCAAACATTGCTCTTTTATCACGCTTCCTTTTATTTTTGATGTAA
CTTCTAATAATTTTGCTGACTTTATCGCTATGAGAGCGATGAGTTTTGATGGCAATCAAGAGAATAACGCTTGGGGTAAT
AGCGTCATGACGCTAAAAAGCGAGATCAATTCGCCTTTTTATCTGAACTTCCACATGCCTACTGATTTTGGTTCAGCCTC
AGCAGGACACACTTTGATACTTGGCTCAACCGGTTCAGGCAAGACGGTGTTTATGTCAATGACCTTGAACGCTATGGGAC
AATTTGCTCACAATTTTCCTGCTAATGTCAGCAAAGACAAACAAAAGCTCACTATGGTCTATATGGACAAGGACTATGGG
GCTTATGGGAACATTGTTGCAATGGGTGGGGAGTATGTCAAGATTGAGCTAGGGACAGATACGGGATTAAATCCTTTTGC
TTGGGCGGCTTGTGTGCAAAAATCCAATGCAACAATGGAGCAAAAACAAACAGCTATTTCTGTTGTCAAAGAGCTTGTAA
AAAACTTAGCAACCAAAAGCGATGAAAAAGATGAGAATGGCAACAGCATCTCTTTTAGCCTAGCCGATTCTAATACGCTT
GCAGCGGCAGTAACCAATCTTATCACAGGAGATATGAACCTAGATTATCCCATCACTCAACTTATTAATGCTTTCGGAAA
AGACCACAATGATCCTAATGGGCTTGTTGCGCGATTAGCGCCTTTTTGCAAATCAACCAATGGTGAATTTCAATGGCTTT
TTGATAATCAAGCAACAGATCGTTTAGATTTTTCAAAAACGATTATTGGCGTTGATGGGTCAAGTTTCCTAGACAATAAT
GATGTTTCGCCCTTTATTTGTTTTTATCTTTTCGCTCGTATTCAAGAGGCAATGGATGGGCGTAGATTTGTCTTAGATAT
TGATGAAGCTTGGAAATATTTAGGCGATCCAAAGGTCGCTTATTTTGTAAGAGACATGCTAAAAACTGCAAGGAAAAGAA
ACGCTATTGTTAGACTTGCGACTCAAAGCATCACTGATCTTTTGGCTTGCCCTATTGCTGATACTATTAGAGAACAATGC
CCTACAAAGATTTTTTTGAGAAACGATGGGGGCAATCTTTCTGATTACCAAAGATTAGCCAATGTTACAGAAAAAGAATT
TGAAATCATCACTAAGGGGTTAGATAGGAAAATTCTCTACAAACAAGATGGAAGCCCTAGCGTTATCGCTAGTTTTAATT
TGAGAGGCATTCCTAAAGAATATTTGAAAATTTTATCCACAGATACTGTATTTGTCAAAGAAATTGACAAGATTATCCAA
AACCATAGTATCATAGATAAATATCAGACCTTGAGACAGATGTATCAACAAATAAAGGAGTATTAA

Protein sequence :
MASKQADEQKKLIIEQEVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSIFILFVTIVLSVILFQAY
EPVLIVAIVIVLVALGFKKDYRLYQRMERAMKFKKPFLFKGVKNKAFMSIFSMKPSKEMANDIHLNPNREDRLVSAANSY
LANNYECFLDDGVILTNNYSLLGTIKLGGIDFLTTSKKDLIELHASIYSVFRNFVTPEFKFYFHTVKKKIVIDETNRDYS
LAFSNDFMRAYNEKQKRESFYDISFFLTIEQDLLDTLNEPVMNKKHFADNNFEEFQRIIRAKLENFKDRIELIEELLSKY
HPTRLKEYTKDGVVYSKQCEFYNFLVGMNEAPFICNRKDLYLKEKMHGGVKEVYFANKHGKILNDDLSEKYFSAIEISEY
APKSQSDLFDKINALDSEFIFMHAYSPKNSQVLKDKLAFTFRRIIISGGSKEQGMTLGCLSELVGNGDITLGSYGNSLVL
FADSFEKMKQSVKECVSSLNAKGFLANAATFSMENYFFAKHCSFITLPFIFDVTSNNFADFIAMRAMSFDGNQENNAWGN
SVMTLKSEINSPFYLNFHMPTDFGSASAGHTLILGSTGSGKTVFMSMTLNAMGQFAHNFPANVSKDKQKLTMVYMDKDYG
AYGNIVAMGGEYVKIELGTDTGLNPFAWAACVQKSNATMEQKQTAISVVKELVKNLATKSDEKDENGNSISFSLADSNTL
AAAVTNLITGDMNLDYPITQLINAFGKDHNDPNGLVARLAPFCKSTNGEFQWLFDNQATDRLDFSKTIIGVDGSSFLDNN
DVSPFICFYLFARIQEAMDGRRFVLDIDEAWKYLGDPKVAYFVRDMLKTARKRNAIVRLATQSITDLLACPIADTIREQC
PTKIFLRNDGGNLSDYQRLANVTEKEFEIITKGLDRKILYKQDGSPSVIASFNLRGIPKEYLKILSTDTVFVKEIDKIIQ
NHSIIDKYQTLRQMYQQIKEY