Name : cagA
Accession : BAD51761.1
PAI name : cag PAI
PAI accession : AB190951
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cytotoxin associated protein A
Function : -
Note : -
Homologs in the searched genomes : 48 hits ( 47 protein-level, 1 DNA-level )
Publication :
-Yamazaki,S., Yamakawa,A. and Azuma,T., "Direct Submission", Submitted (22-SEP-2004) Takeshi Azuma, University of Fukui, Faculty of Medical Sciences, Second depertment of Internal Medicine; Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:81-776-61-8351, Fax:81-776-61-8110).
-Yamazaki,S., Yamakawa,A., Okuda,T., Ohtani,M., Suto,H., Ito,Y., Yamazaki,Y., Keida,Y., Higashi,H., Hatakeyama,M. and Azuma,T., "Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan", J. Clin. Microbiol. 43 (8), 3906-3916 (2005) PUBMED 16081930.
| DNA sequence : | |
ATGACTAACGAAACTATTGATCAAACAAGAACACCAGATCAAACACAAAGCCAAACAGCTTTTGATCCGCAACGATTTAT
CAATAATCTTCAAGTGGCTTTTATTAAAGTTGATAATGTTGTCGCTTCATTTGATCCTAATCAAAAACCAATCGTTGATA
AGAATGATAGGGATAATAGGCAAGCTTTTGAGAAAATCTCGCAGTTAAGGGAGGAATTCGCTAATAAAGCGATCAAAAAT
CCTGCCAAAAAGAATCAGTATTTTTCAAGCTTTATCAGTAAGAGCAGTGATTTAATCAACAAAGACAGTCTCATTGATAC
AGGTTCTTCCATAAAGAGCTTTCAGAAATTTGGGACTCAGCGTTACCAAATTTTTATGAATTGGGTGTCCCATCAAAAAG
ATCCATCTAAAATCAACACCCAAAGAATCCGAAGTTTTATTGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAA
AAAGCGGAGTTTTTGAGGTCTGCCAAACAAGCTTTTGCAGGAATTATCATAGGAAACCAGATCCAATCAGATCAAAAATT
CATGGGCGTGTTTGATGAATCTTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGGGTCTACTGGAGAGCCTACTGGTG
GGGATTGGCTTGATATTTTTTTATCATTTGTGTTTAACAAAAAACAATCTTCCGATCTCAAAGAAACGCTCGATCAAGAA
CCAGTTCCTCATGTCCAACCAGATATAGCCACTACCACCACCGACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCT
TGATGAAAGGGGTAATTTTTCTAAATTCACTCTTGGTGATATGGAAATGTTAGATGTTGAGGGTGTCGCTGACATTGATC
CTAATTACAAGTTCAACCAATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAA
CCTGAAAAAGTTTCATTATTGTATGGGGGCAATGGTGGCCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGGTTATAA
AAACCAACAAGGCGACAATGTGGCTACACTCATTAATGTGCATATGAAAAACGGCAGTGGGTTAGTCATAGCAGGTGGTG
AGAAAGGGGTTAACAACCCTAGTTTTTATCTCTACAAAGAAGACCAGCTCACAGGCTTGAAACAAGCATTGAGCCAAGAA
GAGATCCCAAACAAAGTAGATTTCATGGAATTTCTTGCACAGAACAATGCTAAATTAAATAACTTGAGCAAGAAAGAGAA
AGAAAACTTCCACAATGAGATTGAGAATTTTCAAAAAGACTCTAAGGCTTATTTACACGCCCTAGGGAATGATCACATTG
CTTTTGTTTCTAAAAAAGACAAAAAACATTTAGCTTTAGTTGCTGAGTTTGGTAATGGGGAATTGAGCTACACTCTCAAA
GATTATGGGAAAAAACAAGATAAAGCTTTAGATAGGGAGACAAAAACCACTCTTCAAGGTTACCTAAAACATGATGGCGT
GATGTTTGTTAATTATTCTAATTTCAAATACACCAACGCCTCCAAGAGTCCTGATAAGGGTGTGGGTGCTACGAATGGCG
TTTCCCATTTGGAAGCAAATCTTAGTAAGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTAGTTAT
ATAAGGCGAGACTTAGAAGATAAACTGTGGGCTAAAGGATTGTCCCCACAAGAAGCTAATAAGCTCATCAAAGACTTTTT
GAACAGCAACAAAGAATTGGTTGAAAAAGCTTTAAACTTCAATAAAACTGTAGCTGAAGCTAAAAACACAGGCAATTATG
ACGAAGTGAAAAAAGCTCAGAAAGATCTTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAACGAAAAAA
TTGGAGAGAAAAAGCGATAACAAAAATAGAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCAAT
TATCAATGAAGAGGCTGGTAAGGAAGCAAGAGTAGTCGCTTGCGTTCAGAATCTTAAAGGCATCAGAATGGAATTGTCTG
ATAAGCTTGAAAACATCAACAAGAATTTGAAAGACTTTGATAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGAT
TTCAGCAAGACAGAAGAAACGCTAAAAGCCCTTAAAGACTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAA
AGTTGAAAACCTTAATACAGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAA
GCGACCTTGAAAATTCCATTAAAGATGTGATCATCAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAAGCTGTA
TCAATAGCTAAAGCAACGGGTGATTTCAGTAGGGTAGAGCAAGCGCTAGCCGATCTCAANAATTTCTCAAAAGGACAATT
GACTCAACAAGCTCAAAAAAATGAAGATTTCAATACTGGAAAAAATTCTAAACTATACCAATCCGTTAAGAATGGTGTAA
ATGGAACCCTAGTCGGTAATGGGTTATCTGGAATAGAGGCCACAGCTCTCGCCAAAAAATTTTCGGATATCAAGAAAGAA
TTGAATGAGAAATTTAAAAATTTCAACAACAATAACAATAATGGACTCAAAAACGAACCCATTTATGCTGAAGTTAATAA
AAAGAAAACAGGACAAGTAGCTAACCCTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAAAAGCAAAAATTGACC
GACTCGATCAAATAGCAAGTGGTTTGGGTGGTGTAGGGCAAGCGGGGTTCTCTTTGAAAGGGCATACTAAAGTTGATAAT
CTCAGTAAGGTAGGGCTTTCAGCTAACCATGAACCCATTTACGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAA
AAAGCATGATAAAGTTGGTGATCTCAGTAAGGTAGGGCTTTCAAGGGAGCAAGAATTGAAACAAAAGATTGACAATCTCA
ATCAGGCGGTATCAGAAGCTAAAGCATGTCATTTTGACAACCTAGATCAAATGATAGACAAGCTCAAAGATTCTACAAAA
AAGAATGTTATGAATCTATATGTTGAAAGTGCAAAAAAAGTGCCTACTAGTTTGTCAGCGAAATTGGACGATTATGCTAC
TAACAGCCACACACGCATTAATAGCAATGTCAAAAATGGAGCAATCAATGAAAAAGCGACTGGTATGCTAACGCAAAAAA
ACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAAGCGTTTCTTTGTCAGAGTATGATAAA
ATTGGCTTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCTATAAAAGA
CATTAAGTCTGGCTTTGTGCAATTTTTAACCAATACATTTTCTACAGCATCTTATTACTGCTTGGTGGAAGAAAATGCGA
AGCATGGAATCAAAAATGCTAATACAAAAGGTGGTTTCCAAAAATCTTAA
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| Protein sequence : | |
MTNETIDQTRTPDQTQSQTAFDPQRFINNLQVAFIKVDNVVASFDPNQKPIVDKNDRDNRQAFEKISQLREEFANKAIKN
PAKKNQYFSSFISKSSDLINKDSLIDTGSSIKSFQKFGTQRYQIFMNWVSHQKDPSKINTQRIRSFIENIIQPPISDDKE
KAEFLRSAKQAFAGIIIGNQIQSDQKFMGVFDESLKERQEAEKNGGSTGEPTGGDWLDIFLSFVFNKKQSSDLKETLDQE
PVPHVQPDIATTTTDIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIE
PEKVSLLYGGNGGPEARHDWNATVGYKNQQGDNVATLINVHMKNGSGLVIAGGEKGVNNPSFYLYKEDQLTGLKQALSQE
EIPNKVDFMEFLAQNNAKLNNLSKKEKENFHNEIENFQKDSKAYLHALGNDHIAFVSKKDKKHLALVAEFGNGELSYTLK
DYGKKQDKALDRETKTTLQGYLKHDGVMFVNYSNFKYTNASKSPDKGVGATNGVSHLEANLSKVAVFNLPNLNNLAITSY
IRRDLEDKLWAKGLSPQEANKLIKDFLNSNKELVEKALNFNKTVAEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVTKK
LERKSDNKNRMEAKAQANSQKDKIFAIINEEAGKEARVVACVQNLKGIRMELSDKLENINKNLKDFDKSFDEFKNGKNKD
FSKTEETLKALKDSVKDLGINPEWISKVENLNTALNEFKNGKNKDFSKVTQAKSDLENSIKDVIINQKITDKVDNLNQAV
SIAKATGDFSRVEQALADLXNFSKGQLTQQAQKNEDFNTGKNSKLYQSVKNGVNGTLVGNGLSGIEATALAKKFSDIKKE
LNEKFKNFNNNNNNGLKNEPIYAEVNKKKTGQVANPEEPIYTQVAKKVKAKIDRLDQIASGLGGVGQAGFSLKGHTKVDN
LSKVGLSANHEPIYATIDDLGGPFPLKKHDKVGDLSKVGLSREQELKQKIDNLNQAVSEAKACHFDNLDQMIDKLKDSTK
KNVMNLYVESAKKVPTSLSAKLDDYATNSHTRINSNVKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVSLSEYDK
IGFNQKNMKDYSDSFKFSTKLNNAIKDIKSGFVQFLTNTFSTASYYCLVEENAKHGIKNANTKGGFQKS
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