Name : cagA
Accession : BAD51759.1
PAI name : cag PAI
PAI accession : AB190949
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cytotoxin associated protein A
Function : -
Note : -
Homologs in the searched genomes : 49 hits ( 47 protein-level, 2 DNA-level )
Publication :
-Yamazaki,S., Yamakawa,A. and Azuma,T., "Direct Submission", Submitted (22-SEP-2004) Takeshi Azuma, University of Fukui, Faculty of Medical Sciences, Second depertment of Internal Medicine; Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:81-776-61-8351, Fax:81-776-61-8110).
-Yamazaki,S., Yamakawa,A., Okuda,T., Ohtani,M., Suto,H., Ito,Y., Yamazaki,Y., Keida,Y., Higashi,H., Hatakeyama,M. and Azuma,T., "Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan", J. Clin. Microbiol. 43 (8), 3906-3916 (2005) PUBMED 16081930.
| DNA sequence : | |
ATGACTAACGAAACTATTGATCAAACACCAAGCCAAACAGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGTAGC
TTTTCTTAAAGTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATAAGAATGATAGGGATAACA
GGCAAGCTTTTGAGAAAATCTCGCAACTAAGGGAGGAATTCGCTAATAAAGCGATCAAAAATCCTGCCAAAAAGAATCAG
TATTTTTCAAACTTTATCAGTAAGAGCAATGATTTAATCAACAAAGACAGTCTCATTGATACAGGTTCTTCCATAAAGAG
CTTTCAGAAATTTGGGACTCAGCGTTACCAAATTTTTATGAATTGGGTGTCCCATCAAAAAGATCCATCTAAAATCAACA
CCCAAAGAATCCGAAGTTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAAAAAGCGGAGTTTTTGAGG
TCTGCCAAACAAGCTTTTGCAGGAATTATCATAGGAAACCAGATCCAATCAGATCAAAAATTCATGGGCGTGTTTGAAGA
ATCTTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTACTGGAGAGCCTACTGGTGGGGATTGGCTTGATATTT
TTTTATCATTTGTGTTTAACAAAAAACAATCTTCCGATCTTAAAGAAACACTAAATCAAGAACCAGTTCCTCATGTCCAA
CCAGATATAGCCACTACCACCACTGACATACAAAGCTTACCGCCTGAAGCTAGGGATTTGCTTGATGAAAGGGGTAATTT
TTCTAAATTCACTCTTGGTGATATGGAAATGTTGGATGTTGAGGGCGTCGCTGATATTGATCCTAATTACAAGTTCAACC
AATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTA
TTGTATGGGGGCAATGGTGGCCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGGTTATAAAAACCAACAAGGCGACAA
TGTGGCTACACTCATTAATGTGCATATGAAAAACGGCAGTGGGTTAGTCATAGCAGGTGGTGAGAAAGGGGTTAACAACC
CTAGTTTTTATCTCTACAAAGAAGACCAGCTCACAGGCTTGAAACAAGCATTGAGCCAAGAAGAGATCCAAAACAAAGTA
GATTTCATGGAATTTCTTGCACAAAACAATGCTAAATTAGATAACTTGAGCAAGAAAGAGAAAGAAAAATTCCAAAATGA
GATTGAAGATTTTCAAAAAGACTCTAAGGCTTATTTAGATGCCCTAGGGAATGATCACATTGCTTTTGTTTCTAAAAAAG
ACAAAAAACATTTAGCTTTAGTTGCTGAGTTTGGTAATGGGGAATTGAGCTACACTCTCAAAGATTATGGGAAAAAACAA
GATAAAGCTTTAGATAGGGAGACAAAAACCACTCTTCAAGGTAACCTAAAACATGATGGCGTGATGTTTGTTAATTATTC
TAATTTCAAATACACCAACGCCTCCAAGAGTCCTGATAAGGGTGTGGGTGCTACGAATGGCGTTTCCCATTTGGAAGCAA
ATCTTAGCAAGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCAATAGTTATATAAGGCGAGACTTAGAA
GATAAACTGATGGCTAAAGGATTGTCCCCACAAGAAGCTAATAAGCTCATCAAAGACTTTTTGAACAGCAACAAAGAATT
GGTTGAAAAAGCTTTAAACTTCAATAAAACTGTAGCTGAAGCTAAAAACACAGGCAATTATGATGAAGTGAAAAAAGCTC
AGAAAGATCTTGAAAAATCTATAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGCGAAAAAATTGGAGAGCAGAAACGAC
AACAAAAATAGAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCACTTATCAATCAAGAGGCTAG
TAAGGAAGCAAGAGCGACCGCTTGCGTTCAGAATCTTAAAGGCATCAGGAGCGAATTGTCTGATAAGCTTGAAAATATCA
ACAAGAATTTGAAAGACTTTGATAAATCTTTTGATGAACTCAAAAATGGCAAAAATAATGATTTCAGCAAGGCAGAAGAA
ACGCTAAAAGCCCTTAAAGACTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAAAATTGAAAATCTTAATGC
AGCTTTGAATGATTTCAAAAATGGTAAAAATAAGGATTTCAGCAAGGTAACACAAGCAAAAAGCGACCTTGAAAATTCCA
TTAAAGATGTGATCATCAATCAAGAGATAACGGATAAAGTTGACAATCTCAATCAAGCTGTATCAATAGCTAATAGCACA
GGCGATTTCAGTGGGGTAGAGCAAGCGCTAGCCGATCTCAAGAATTTCTCAAAAGGACAATTGACTCAACAAGCTCAAAA
AAATGAAGATTTCAATACTGGAAAAAATTCTGAACTATACCAATCCGTTAAGAATGGTGTAAATGGAACCCTAGTCGGTA
ATGGGTTATCTAAAGCAGAAGCCACAACTCTTTCTAAAAACTTTTCGGACATCAAGAAAGAGTTGAATGCAAAACTTGGA
AATTTCAATAACAATAATAATAATGGACTCAAAAACGAACCCATTTATGCTAAAGTTAATAAAGAGAAAACAGGACAAGT
AGCTAACCTTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAAAAGCAAAAATTGACCGACTCGATCAAATAGCAA
GTGGTTTGGGTGGTGTAGGGCAAGCGGGATTCTCTTTGAAAGGGCATACTAAAGTTGGTGATCTCAGTAAGGTAGGGCTT
TCAAGGGAGCAAGAATTGAAACAGAAGATTGACAATCTCAATCAAGCGGTATCAGAAGCTAAAGCATGTCATTTTGACAA
CCTAGAGCAAACGATAGACAAGCTCAAAGATTCTACAAAAAAGAATGTTATGAATCTATATATTGAAAGTGCAAAAAAAG
TGCCTGCTAGTTTGTCAGCGAAACTAGACAATTACGCTACTAACAGCCACACACGCATTAATAGCAATGTCCGAAATGGA
ACAATCAATGAAAAAGTGACTGGTATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGC
ACATAATGTGGGAAGTGCTCCTTTGTCAGCGTATGATAAAATTGGATTCAACCAAAAGAATATGAAAGATTATTCTGATT
CGTTCAAGTTTTCCACCAGGTTGAGCAATGCCGTAAAAGACATTAAGTCTGGCTTTGTGCAATTTTTAACCAATGCATTT
TCTACAGGATCTTACAGCTTGATGAAAGCAAATGCGGAACATGGAGTCAAAAATACTAATACAAAAGGTGGTTTCCAAAA
ATCTTAA
|
| Protein sequence : | |
MTNETIDQTPSQTAFNPQQFINNLQVAFLKVDNAVASFDPDQKPIVDKNDRDNRQAFEKISQLREEFANKAIKNPAKKNQ
YFSNFISKSNDLINKDSLIDTGSSIKSFQKFGTQRYQIFMNWVSHQKDPSKINTQRIRSFMENIIQPPISDDKEKAEFLR
SAKQAFAGIIIGNQIQSDQKFMGVFEESLKERQEAEKNGEPTGEPTGGDWLDIFLSFVFNKKQSSDLKETLNQEPVPHVQ
PDIATTTTDIQSLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSL
LYGGNGGPEARHDWNATVGYKNQQGDNVATLINVHMKNGSGLVIAGGEKGVNNPSFYLYKEDQLTGLKQALSQEEIQNKV
DFMEFLAQNNAKLDNLSKKEKEKFQNEIEDFQKDSKAYLDALGNDHIAFVSKKDKKHLALVAEFGNGELSYTLKDYGKKQ
DKALDRETKTTLQGNLKHDGVMFVNYSNFKYTNASKSPDKGVGATNGVSHLEANLSKVAVFNLPNLNNLAINSYIRRDLE
DKLMAKGLSPQEANKLIKDFLNSNKELVEKALNFNKTVAEAKNTGNYDEVKKAQKDLEKSIRKREHLEKEVAKKLESRND
NKNRMEAKAQANSQKDKIFALINQEASKEARATACVQNLKGIRSELSDKLENINKNLKDFDKSFDELKNGKNNDFSKAEE
TLKALKDSVKDLGINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVIINQEITDKVDNLNQAVSIANST
GDFSGVEQALADLKNFSKGQLTQQAQKNEDFNTGKNSELYQSVKNGVNGTLVGNGLSKAEATTLSKNFSDIKKELNAKLG
NFNNNNNNGLKNEPIYAKVNKEKTGQVANLEEPIYTQVAKKVKAKIDRLDQIASGLGGVGQAGFSLKGHTKVGDLSKVGL
SREQELKQKIDNLNQAVSEAKACHFDNLEQTIDKLKDSTKKNVMNLYIESAKKVPASLSAKLDNYATNSHTRINSNVRNG
TINEKVTGMLTQKNPEWLKLVNDKIVAHNVGSAPLSAYDKIGFNQKNMKDYSDSFKFSTRLSNAVKDIKSGFVQFLTNAF
STGSYSLMKANAEHGVKNTNTKGGFQKS
|
|
