Name : cagA
Accession : BAD51753.1
PAI name : cag PAI
PAI accession : AB190943
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cytotoxin associated protein A
Function : -
Note : -
Homologs in the searched genomes : 49 hits ( 47 protein-level, 2 DNA-level )
Publication :
-Yamazaki,S., Yamakawa,A. and Azuma,T., "Direct Submission", Submitted (22-SEP-2004) Takeshi Azuma, University of Fukui, Faculty of Medical Sciences, Second depertment of Internal Medicine; Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:81-776-61-8351, Fax:81-776-61-8110).
-Yamazaki,S., Yamakawa,A., Okuda,T., Ohtani,M., Suto,H., Ito,Y., Yamazaki,Y., Keida,Y., Higashi,H., Hatakeyama,M. and Azuma,T., "Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan", J. Clin. Microbiol. 43 (8), 3906-3916 (2005) PUBMED 16081930.
| DNA sequence : | |
ATGACTAACGAAACTATTGATCAAACACCAAGCCAAACAGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGTAGC
TTTTCTTAAAGTTGATAACACTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATAAGAATGATAGGGATAACA
GGCAAGCTTTTGAGAAAATCTCGCAACTAAGGGAGGAATTCGCTAATAAAGCGATCAAAAATCCTGCCAAAAAGAATCAG
TATTTTTCAAGCTTTATCAGTAAGAGCAGTGATTTAATCAACAAAGACAGTCTCATTGATACAGGTTCTTCCATAAAGAG
CTTTCAGAAATTTGGGACTCAGCGTTACCAAATTTTTATGAATTGGGTGTCCCATCAAAAAGATCCATCTAAAATCAACA
CCCAAAGAATCCGAAGTTTTATTGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAAAAAGCGGAGTTTTTGAGG
TCTGCCAAACAAGCTTTTGCAGGAATTATCATAGGAAACCAGATCCAATCAGATCAAAAATTCATGGGCGTGTTTGATGA
ATCTTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGGGTCTACTGGAGAGCCTACTGGTGGGGATTGGCTTGATATTT
TTTTATCATTTGTGTTTAACAAAAAACAATCTTCCGATCTCAAAGAAACGCTCGATCAAGAACCAGTTCCTCATGTCCAA
CCAGATATAGCCACTACCACCACCGACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTT
TTCTAAATTCACTCTTGGTGATATGGAAATGTTAGATGTTGAGGGTGTCGCTGACATTGATCCTAATTACAAGTTCAACC
AATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTA
TTGTATGGGGGCAATGGTGGTCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGGTTATAAAAACCAACAAGGCAACAA
TGTGGCTACACTCATTAATGTGCATATGAAAAACGGCAGTGGGTTAGTCATAGCAGGTGGTGAGAAAGGGGTTAACAACC
CTAGTTTTTATCTCTACAAAGAAGACCAGCTCACAGGCTTGAAACAAGCATTGAGTCAAAAAGAGATCCAAAACAAAGTG
GATTTCATGGAATTTCTTGCAAAAAACAACGCTAGATTAGATAACTTGAGCGAGAAAGAGAAAGAAAAATTCCAAACTGA
GATTGAAGATTTCCAAAAAAACCCTAAGGCTTATTTAGACGCCCTAGGGAATGATCATATTGCTTTTGTTTCTAAAAAAG
ACAAAAAACATTTAGCTTTAGTTACTGAGTTTGGTAATGGGGAATTGAGCTACACTCTCAAAGATTATGGGAAAAAACAA
GATAAAGCTTTAGATAGGGAGACAAAAACCACTCTTCAAGGTAACCTAAAACATGATGGCGTGATGTTTGTTAATTATTC
TAATTTCAAATACACCAACGCCTCCAAGAGTCCTGATAAGGGTGTGGGTACTACGAATGGCGTTTCCCATTTGGAAGCAA
ATTTTAGCAAGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTAGTTATATAAGGCGAGACTTAGAA
GGTAAACTGTCGGCTAAAGGATTGTCCCTACAAGAAGCTAATAAGCTCATCAAAGACTTTTTGAACAGCAACAAAGAATT
GGTTGAAAAAGCTTTAAACTTCAATAAAACTGTAGCTGAAGCTAAAAACACAGGCAATTATGACGAAGTGAAAAAAGCTC
AGAAAGATCTTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAACGAAAAAAATGGAGAGCAAAAGTGGC
AACAAAAATAAAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCAATTATCAATAAAGAGGCTAG
TAGGGAAGCAAGAGCGGCCACTTACACTCAGAGTCTTAAAATTATCAGAAGGGAATTGCATGATAAGCTTGAAAACATCA
ACAAGAATTTGAATGCCTTTGATAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAA
ACGCTAAAAGCCCTTAAAGACTCGGTGAAAGATTTAGGCATCAATCCAGAATGGATTTCAAAAGTTGAAAACCTTAATAC
AGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAATACAAGCAAAAAGCGACCTTGAAAATTCCA
TTAAAGATGTGATCATCAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAAGCTATATCAATAGCTAAGGCAACA
GGCGATTTCAGTGGGGTAGAGCAAGCGCTAGCCGATCTCAAGAATTTCTCAAAAGGACAATTGACTCAACAAGCTCAAAA
AAATGAAGATTTCAATACTGGAAAAAATTCTGAACTATACCAATCCGTTAAGAATGGTGTAAATGGAACCCTAGTCGGTA
ATGGGTTATCTAAAGCAGAAGCCACAACTCTTTCTAAAAACTTTTCGGACATCAAGAAAGAGTTGAATGCAAAACTTGGA
AATTTCAATAACAATAATAATGATGGACTCAAAAATAGCATAGAACCCATTTATGCTAAAGTTAATAAAAAGAAAGCAGG
ACAAGCAGCTAGCCCTGAAGAGTCCATTTATACTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCAACTCAATCAAG
CAGCAAGTGGTTTCGGTAATGTAGGGCAAGCGGGATTCCCTTTGAAAAGGCATACTAAAGCTGATGATCTCAGTAAGGTA
GGGCTTTCAGCTAACCATGAACCCATTTACGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAAGCATGATAA
AGCTGATGATCTCAGTAAGGTAGGGCTTTCAAGGGAGCAAGAATTGACTCAGAAAATTGAAAATCTCAACCAGGTGCTAC
CAGAAGCTAAAGTATGTCATTTTGACAACCTAGAGCAAATGATAGACAAGCTCAAAGATTCTACAAAAAAGAATGTTATG
AATCTATATGTTGAAAGTGCAAAAAAAGTGCCTACTAGTTTGTCAGCGAAATTGGACAATTACGCTACTAACAGCCACAC
ACGCATTAATAGCAATATCCGAAATGGAACAATCAACGAAAAAGAGACTAGCATGTTAATGCGAAAAAACCCTGAGTGGC
TTAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAAGTGCTCCTTTGTCAGCGTATGATAAAATTGGATTCAAC
CAAAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAGGTTGAGCAATGCCGTAAAAGACATTAAGTCTGG
CTTTGTGCAATTTTTAACCAATATATTTTCTATGGGATCTTACAGCTTGATGAAAGCAAGTGTGGAACATGGAGTCAAAA
ATACTAATACAAAAGGTGGTTTCCAAAAATCTTAA
|
| Protein sequence : | |
MTNETIDQTPSQTAFNPQQFINNLQVAFLKVDNTVASFDPDQKPIVDKNDRDNRQAFEKISQLREEFANKAIKNPAKKNQ
YFSSFISKSSDLINKDSLIDTGSSIKSFQKFGTQRYQIFMNWVSHQKDPSKINTQRIRSFIENIIQPPISDDKEKAEFLR
SAKQAFAGIIIGNQIQSDQKFMGVFDESLKERQEAEKNGGSTGEPTGGDWLDIFLSFVFNKKQSSDLKETLDQEPVPHVQ
PDIATTTTDIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSL
LYGGNGGPEARHDWNATVGYKNQQGNNVATLINVHMKNGSGLVIAGGEKGVNNPSFYLYKEDQLTGLKQALSQKEIQNKV
DFMEFLAKNNARLDNLSEKEKEKFQTEIEDFQKNPKAYLDALGNDHIAFVSKKDKKHLALVTEFGNGELSYTLKDYGKKQ
DKALDRETKTTLQGNLKHDGVMFVNYSNFKYTNASKSPDKGVGTTNGVSHLEANFSKVAVFNLPNLNNLAITSYIRRDLE
GKLSAKGLSLQEANKLIKDFLNSNKELVEKALNFNKTVAEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVTKKMESKSG
NKNKMEAKAQANSQKDKIFAIINKEASREARAATYTQSLKIIRRELHDKLENINKNLNAFDKSFDEFKNGKNKDFSKAEE
TLKALKDSVKDLGINPEWISKVENLNTALNEFKNGKNKDFSKVIQAKSDLENSIKDVIINQKITDKVDNLNQAISIAKAT
GDFSGVEQALADLKNFSKGQLTQQAQKNEDFNTGKNSELYQSVKNGVNGTLVGNGLSKAEATTLSKNFSDIKKELNAKLG
NFNNNNNDGLKNSIEPIYAKVNKKKAGQAASPEESIYTQVAKKVNAKIDQLNQAASGFGNVGQAGFPLKRHTKADDLSKV
GLSANHEPIYATIDDLGGPFPLKKHDKADDLSKVGLSREQELTQKIENLNQVLPEAKVCHFDNLEQMIDKLKDSTKKNVM
NLYVESAKKVPTSLSAKLDNYATNSHTRINSNIRNGTINEKETSMLMRKNPEWLKLVNDKIVAHNVGSAPLSAYDKIGFN
QKNMKDYSDSFKFSTRLSNAVKDIKSGFVQFLTNIFSMGSYSLMKASVEHGVKNTNTKGGFQKS
|
|
