PAI Gene Information


Name : HP0547
Accession : BAD14045.1
PAI name : cag PAI
PAI accession : AB120425
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to H.pylori 26695 gene HP0547:cag26, J99 gene JHP0495, NCTC11638 gene cag-A
Homologs in the searched genomes :   48 hits    ( 47 protein-level,   1 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGACTAACGAAACTATTGACCAACAACCACAAACCGAAGCGGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGT
AGCTTTTCTTAAAGTTGATAACGCTGTCGCTTCATTCGATCCTGATCAAAAACCAATCGTTGATAAGAACGATAGGGATA
ACAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAATGAGTTAATCAACAAAGACAATCTCATTGACGTGGAATCTTCCACAAA
GAGCTTTCAGAAATTTGGGGATCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAACATACCATACAACCCCCTATCCCTGATGACAAAGAAAAAGCAGAGTTTTTG
AAATCCGCCAAACAATCTTTTGCAGGAATCATCATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGGCGTGTTTGA
TGAATCTTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGGGCCTACTGGTGGGGCTTGGTTGGATATTTTTTTATCAT
TTATATTTGACAAAAAACAATCTTCTGATGTTAAAGAAGCAATCAATCAAGAACCACTTCCCCATGTCCAACCAGATATA
GCCACTAGCACCACTCACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGCGTCGCCGACATGGATCCCAATTACAAGTTCAATCAATTATTGA
TTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATGATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGCG
GGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTCATAAAGACCAACAAGGTAACAATGTGGCTAC
AATAATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTT
ATCTCTACAAAGAAGACCAACTCACAGGTTCACAACGAGCATTGAGTCAAGAAGAGATCCTAAACAAAGTAGATTTCATG
GAATTTCTTGCACAAAACAATGCTAAATTAGACAACTTGAGCGAGAAAGAGAAAGAAAAATTCCGAACTGAGATTAAGGA
TTTTCAAAAAGACTCTAAGCCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTAAAAAAGACCCAAAAC
ATTCAGCTTTAATCACTGAGTTTAATAAGGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAAAGCT
TTAGATAGGGAGAAAAATGTCACTCTCCAAGGTAACCTAAAACATGATGGCGTGATGTTTGTTAATTATTCTAATTTCAA
ATACACCAACGCCTCCAAGAGTCCCAATAAAGGTGTAGGCGTTACGAATGGCGTTTCCCATTTAGAAGCAGGCTTTAGCA
AGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTGGAGTCGTAAGGCGGGATTTAGAGGATAAACTA
ATCGCTAAAGGATTGTCCCCACAAGAAGCTAATAAACTCGTCAAAGACTTTTTGAGCAGCAACAAAGAATTGGTTGGAAA
AGCTTTAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAACACAGGCAACTATGACGAGGTGAAACGAACTCAGAAAGATC
TTGAAAAATCTCTAAAGAAACGAGAGCATTTGGAGAAAGGTGTAGTGAAAAATTTGGAGAGCAAAAGCGGCAACAAAAAT
AAAATGGAAGCAAAATCTCAAGCTAACAGCCAAAAAGATGAGATTTTTGCGTTGATCAATAAAGAGGCTAATAGGGATGC
AAGAGCAATCACTTACGCTCAAAATCTTAAAGGCATCAAAAGGGAATTGTCTGATAAACTTGAAAATATCAACAAGGATT
TGAAAGACTTTAGTAAATCTTTTGATGGATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAAACGCTAAAA
GCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCGGAATGGATTTCAAAAGTTGAAAACCTTAATGCAGCTTTGAA
TGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAAGCGACCTTGAAAATTCCATTAAAGATG
CGATCATCAATCAAAAGATAACGGATAAAGTTGATGATCTCAATCAAGCGGTATCAGTGGCTAAAATAGCGGGTGATTTC
AGTGGGATAGAGCAAGCGTTAGCCGATCTCAAAAATTTCTCAAAGGAGCAATTGGCTCAACAAGCTCAAAAAAATGAAGA
TTTCAATACTGGAAAAAATTCTGCACTATACCAATCCGTTAAGAATGGTGTAAACGGAACCCTAGTCGGTAATGGGTTAT
CTAAAGCAGAAGCCACAACTCTTTCTAAAAACTTTTCGGACATCAAGAAAGAGTTGAATGCAAAACTTGGAAATTTCAAT
AACAATAACAATAATGGACTCAAAAACGAACCCATTTATGCTAAAGTTAATAAAAAGAAATCAGGACAAGCAGCTAGCCC
TGAAGAACCCATTTACGCTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCGACTCAATCAAATAGCAAGTGGTTTGG
GTGGTGTAGGGCAAGCAGCGGGCTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCGATCGGTT
AGCCCTGAACCCATTTATGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCT
CAGTAAGGTAGGGCTTTCAAGGAATCAAGAATTGGCTCAGAAAATTGACAGTCTCAATCAAGCGGTATCAAAAGCTAAAG
CAGGTTTTTTTGGCAATCTAGAGCAAACGATAGACAAGCTCAAAGATTCTACAAAACACAATCCTGTGAATCTATGGGTT
GAAGGTGCAAAAAAAGTGCCTGCTAGTTTGTCGGCGAAACTAGACAATTACGCTACTAACAGCCACACACGCATTAACAG
CGATATCAAAAATGGAGCAATCAATGAAAAAGCGACCGGTATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGA
ATGATAAGATAGTTGCGCATAATGTAGGAAGCGTTCCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAATATG
AAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCTGTAAAAGACGTTAAGTCTGGCTTTACGCAAAT
TTTAGCCAATGCATTTTCTACAGGATATTACTGCTTGGCGAGGGAAAATACGGAACATGGAATCAAAAATGTTAATACAA
AAGGTGGTTTCCAAAAATCTTAA

Protein sequence :
MTNETIDQQPQTEAAFNPQQFINNLQVAFLKVDNAVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKN
QYFSDFINKSNELINKDNLIDVESSTKSFQKFGDQRYRIFTSWVSHQNDPSKINTRSIRNFMEHTIQPPIPDDKEKAEFL
KSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGAWLDIFLSFIFDKKQSSDVKEAINQEPLPHVQPDI
ATSTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADMDPNYKFNQLLIHNNALSSVLMGSHDGIEPEKVSLLYA
GNGGFGAKHDWNATVGHKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEILNKVDFM
EFLAQNNAKLDNLSEKEKEKFRTEIKDFQKDSKPYLDALGNDRIAFVSKKDPKHSALITEFNKGDLSYTLKDYGKKADKA
LDREKNVTLQGNLKHDGVMFVNYSNFKYTNASKSPNKGVGVTNGVSHLEAGFSKVAVFNLPNLNNLAITGVVRRDLEDKL
IAKGLSPQEANKLVKDFLSSNKELVGKALNFNKAVAEAKNTGNYDEVKRTQKDLEKSLKKREHLEKGVVKNLESKSGNKN
KMEAKSQANSQKDEIFALINKEANRDARAITYAQNLKGIKRELSDKLENINKDLKDFSKSFDGFKNGKNKDFSKAEETLK
ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSIKDAIINQKITDKVDDLNQAVSVAKIAGDF
SGIEQALADLKNFSKEQLAQQAQKNEDFNTGKNSALYQSVKNGVNGTLVGNGLSKAEATTLSKNFSDIKKELNAKLGNFN
NNNNNGLKNEPIYAKVNKKKSGQAASPEEPIYAQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKRHDKVDDLSKVGRSV
SPEPIYATIDDLGGPFPLKRHDKVDDLSKVGLSRNQELAQKIDSLNQAVSKAKAGFFGNLEQTIDKLKDSTKHNPVNLWV
EGAKKVPASLSAKLDNYATNSHTRINSDIKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNM
KDYSDSFKFSTKLNNAVKDVKSGFTQILANAFSTGYYCLARENTEHGIKNVNTKGGFQKS