PAI Gene Information


Name : HP0547
Accession : BAD13990.1
PAI name : cag PAI
PAI accession : AB120423
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to H.pylori 26695 gene HP0547:cag26, J99 gene JHP0495, NCTC11638 gene cag-A
Homologs in the searched genomes :   46 hits    ( 45 protein-level,   1 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGACTAACGAAACTATTGATCAAACACCAAGCCAAACAGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGTAGC
TTTTCTTAAAGTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATAAGAATGATAGGGATAACA
GGCAAGCTTTTGAGAAAATCTCGCAACTAATGGAGGAATTCGCTAATAAAGCGATCAAAAATCCTGCCAAAAAGAATCAG
TATTTTTCAAACTTTATCAGTAAGAGCAATGATTTAATCAACAAAGACAGTCTCATTGATATAGGTTCTTCCACAAAGAG
CTTTCAGAAATTTGGGACTCAGCGTTACCAAATTTTTATGAATTGGGTGTCCCATCAAAAAGATCCATCTAAAATCAACA
CCCAAAGAATCCGAAGTTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAAAAAGCGGAGTTTTTGAGG
TCTGCCAAACAATCTTTTGCAGGAATTATCATAGGAAACCAGATCCAATCAGATCAAAAATTCATGGGCGTGTTTGAAGA
ATCTTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTACTGGAGAGCCTACTGGTGGGGATTGGCTTGATATTT
TTTTATCATTTGTGTTTAACAAAAAACAATCTTCCGATCTTAAAGAAACACTAAATCAAGAACCAGTTCCTCATGTCCAA
CCAGATATAGCCACTACCACCACTGACATACAAAGCTTACCGCCTGAAGCTAGGGATTTGCTTGATGAAAGGGGTAATTT
TTCTAAATTCACTCTTGGTGATATGGAAATGTTGGATGTTGAGGGCGTCGCTGATATTGATCCTAATTACAAGTTCAACC
AATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTA
TTGTATGGGGGCAATGGTGGCCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGGTTATAAAAACCAACAAGGCGACAA
TGTGGCTACACTCATTAATGTGCATATGAAAAACGGCAGTGGGTTAGTCATAGCAGGTGGTGAGAAAGGGGTTAACAACC
CTAGTTTTTATCTCTACAAAGAAGACCAGCTCACAGGCTTGAAACAAGCATTGAGCCAAGAAGAGATCAAAAACAAAGTA
GATTTCATGGAATTTCTTGCACAAAACAATGCTAAATTAGATAACTTGAGCAAGAAAGAGAAAGAAAAATTCCAAAATGA
GATTGAAGATTTTCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCACATTGCTTTTGTTTCTAAAAAAG
ACAAAAAACATTTAGCTTTAGTTGCTGAGTTTGGTAATGGGGAATTGAGCTACACTCTCAAAGATTATGGGAAAAAACAA
GATAAAGCTTTAGATAGGGAGACAAAAACCACTCTTCAAGGTAACCTAAAACATGATGGCGTGATGTTTGTTAATTATTC
TAATTTCAAATACACCAACGCCTCCAAGAGTCCTGATAAGGGTGTGGGTGCTACGAATGGCTGTTTCCCTTTGGAAGCAA
ATCTTAGTAAGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTAGTTATATAAGGCGAGACTTAGAA
GATAAACTGTGGGCTAAAGGATTGTCCCCACAAGAAGTTAATAAGCTCATCAAAGACTTTTTGAACAGCAACAAAGAATT
GGTTGAAAAAGCTTTAAACTTCAATAAAACTGTAGCTGAAGCTAAAAACACAGGCAATTATGACGAAGTGAAAAAAGCTC
AGAAAGATCTTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAACGAAAAAATTGGAGAGAAAAAGCGAT
AACAAAAATAGAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCAATTATCAATGAAGAGGCTGG
TAAGGAAGCAAGAGTAGCCGCTTGCGTTCAGAATCTTAAAGGCATCAGAATGGAATTGTCTGATAAGCTTGAAAACATCA
ACAAGAATTTGAAAGACTTTGATAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGACAGAAGAA
ACGCTAAAAGCCCTTAAAGACTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAAAGTTGAAAACCTTAATAC
AGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAAGCGACCTTGAAAATTCCA
TTAAAGATGTGATCATCAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAAGCTGTATCAATAGCTAAAGAAACG
GGTGATTTCAGTAGGGTAGAGCAAGCGCTAGCCGATCTCAAGAATTTCTCAAAAGGGCAATTGACTCAACAAGCTCAAAA
AAATGAAGATTTCAATACTGGAAAAAATTCTAAACTATACCAATCCGTTAAGAATGGTGTAAATGGAACCCTAGTCGGTA
ATGGGTTATCTGGAATAGAGGCCACAGCTCTCGCCAAAAAATTTTCGGATATCAAGAAAGAATTGAATGAGAAATTTAAA
AATTTCAACAACAATAACAATAATGGACTCAAAAACGAACCCATTTATGCTGAAGTTAATAAAAAGAAAACAGGACAAGT
AGCTAGCCCTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAAAAGCAAAAATTGACCGACTCGATCAAATAGCAA
GTGGTTTGGGTGGTGTAGGGCAAGCGGGGTTCTCTTTGAAAGGGCATACTAAAGTTGATGATCTCAGTAAGGTAGGGCTT
TCAGCTAACCATGAACCCATTTACGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAAGCATACTAAAGTTGA
TGATCTCAGTAAGGTAGGGCTTTCAGCTAACCATGAACCCATTTACGCTACGATTGATGATCTCGGCGGACCTTTCCCTT
TGAAAAAGCATACTAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAGCTAACCATGAACCCATTTACGCTACGATTGAT
GATCTCGGCGGACCTTTCCCTTTGAAAAAGCATGATAAAGTTGGTGATCTCAGTAAGGTAGGGCTTTCAAGGGAGCAAGA
ATTGAAACAAAAGATTGACAATCTCAATCAGGCGGTATCAGAAGCTAAAACAGGTCATTTTGACAACCTAGATCAAATGA
TAGACAAGCTCAAAGATTCTACAAAAAAGAATGTTATGAATCTATATGTTGAAAGTGCAAAAAAAGTGCCTACTAGTTTG
TCAGCGAAATTGGACGATTATGCTACTAACAGCCACACACGCATTAATAGCAATGTCAAAAATGGAGCAATCAATGAAAA
AGCGACTGGTATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAA
GCGCTTCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCC
ACCGAGTTGAACAATGCTATAAAAGACATTAAGTCTGGCTTTGTGCAATTTTTAACCAATACATTTTCTACAGCATCTTA
TTACTGCTTGGCGGAAGAAAATGCGAAGCATGGAATCAAAAATGCTAATACAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence :
MTNETIDQTPSQTAFNPQQFINNLQVAFLKVDNAVASFDPDQKPIVDKNDRDNRQAFEKISQLMEEFANKAIKNPAKKNQ
YFSNFISKSNDLINKDSLIDIGSSTKSFQKFGTQRYQIFMNWVSHQKDPSKINTQRIRSFMENIIQPPISDDKEKAEFLR
SAKQSFAGIIIGNQIQSDQKFMGVFEESLKERQEAEKNGEPTGEPTGGDWLDIFLSFVFNKKQSSDLKETLNQEPVPHVQ
PDIATTTTDIQSLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSL
LYGGNGGPEARHDWNATVGYKNQQGDNVATLINVHMKNGSGLVIAGGEKGVNNPSFYLYKEDQLTGLKQALSQEEIKNKV
DFMEFLAQNNAKLDNLSKKEKEKFQNEIEDFQKDSKAYLDALGNDHIAFVSKKDKKHLALVAEFGNGELSYTLKDYGKKQ
DKALDRETKTTLQGNLKHDGVMFVNYSNFKYTNASKSPDKGVGATNGCFPLEANLSKVAVFNLPNLNNLAITSYIRRDLE
DKLWAKGLSPQEVNKLIKDFLNSNKELVEKALNFNKTVAEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVTKKLERKSD
NKNRMEAKAQANSQKDKIFAIINEEAGKEARVAACVQNLKGIRMELSDKLENINKNLKDFDKSFDEFKNGKNKDFSKTEE
TLKALKDSVKDLGINPEWISKVENLNTALNEFKNGKNKDFSKVTQAKSDLENSIKDVIINQKITDKVDNLNQAVSIAKET
GDFSRVEQALADLKNFSKGQLTQQAQKNEDFNTGKNSKLYQSVKNGVNGTLVGNGLSGIEATALAKKFSDIKKELNEKFK
NFNNNNNNGLKNEPIYAEVNKKKTGQVASPEEPIYTQVAKKVKAKIDRLDQIASGLGGVGQAGFSLKGHTKVDDLSKVGL
SANHEPIYATIDDLGGPFPLKKHTKVDDLSKVGLSANHEPIYATIDDLGGPFPLKKHTKVDDLSKVGLSANHEPIYATID
DLGGPFPLKKHDKVGDLSKVGLSREQELKQKIDNLNQAVSEAKTGHFDNLDQMIDKLKDSTKKNVMNLYVESAKKVPTSL
SAKLDDYATNSHTRINSNVKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSASLSEYDKIGFNQKNMKDYSDSFKFS
TELNNAIKDIKSGFVQFLTNTFSTASYYCLAEENAKHGIKNANTKGGFQKS