PAI Gene Information


Name : HP0527
Accession : BAD13970.1
PAI name : cag PAI
PAI accession : AB120423
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to virB10, H.pylori 26695 gene HP0527:cag7, J99 gene JHP0476, NCTC11638 gene ORF13andORF14:cag-Y
Homologs in the searched genomes :   34 hits    ( 33 protein-level,   1 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAACCCAACAAGATTCACCCCAAGATTTATCCAATGAAGAAGC
GACAGAAGTCAATCGCTTTGAAGATTCTTCAAAAGAATCCGAAGAAAGCTCAGATCATTATCTTGACAACCCCACAGAAA
CTAAAACCAATTTTGATGAATACGAGTTAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCT
AGCAATGGCAGTCTGGCAGACAAGTTATTTAAAAAAGCCAGAAAATTAGTTGATAATAAAAGACCTTTCACTCAGCAAAA
GAATTTAGATGAAGAAACCCAAGAACTGAACGAAGAAGACGATCAAGAAAATAATGGGTATCAAGAAGAAACTCAAATAG
ACTTAATTGATGATGAAACTTCTCAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCGACAGAAGTC
AATCGCTTTGAAGATTCTTCAAAAGAATCCGAAGAAAGCTCAGATCATTATCTTGACAACCCCACAGAAACTAAAACCAA
TTTTGATGAAGACAAGTCAGAAGAAATAACTAACGACTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATATA
TTATTAGTGGCATTGTAGTCGCTGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTCATGCCTTTG
GAAGATAAAAGTTCTCGTTTTAGCAAAGACAGGAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCG
ATTGCTGAAAGAACGGAATGAAAAAGGCAATATGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTAT
ACAACTATTTAAATATTGCAGAAATTGAGGACAAAAACCCATTGAGAGCCTTTTATGAATGTATCAGTAATGGTGGCAAC
TATGAAGAGTGTTTGAAGCTTATCAAAGACAAAAAACTTCAAGATCAAATGAAAAAGACTCTAGAGGTTTATAAAGACTG
CATCAAAAATGCCAAAACTGAAGAGGAAAGGATCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTAC
TGAACCAACAAAAAGTTCAAGTGGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCCTAAAA
CTCATAAATGACCCTGAGATTAGAGAGAAATTCCGTAAGGAATTAGGGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTG
TATCAAAAACGCCAAAACAGAAGCTGAGAAAAATGAATGCTTGAAAGGCTTGTCTAAAGAAGCTATAGAAAGATTGAAAC
AGCAAGCACTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCTTGAAAAATATTCCCCAAGACTTG
CAAAAAGAACTACTAGCTGATATGAGCGTTAAGGCTTACAAGGACTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAACA
AGAATGCGACAAATTGCTCACGCCTGAAGCGAAAAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAA
CCGATGAAGAACGAAAAAAGTGTTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGTCTGAAA
GCTTATAAAGACTGCACATCTCAAGCCAAAACTGAAGATGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAA
AAAACTTTTAGAAGAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGATGAGA
AAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTG
GATTGCGTATCTCAAGCCAAAACTGAAGATGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAGGAAACTTTT
AGAGAAACAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAG
ACTTGCAGAAAAAGGTTTTAGCCAAAGAGAGCGTTAGGGTTTATTTGGATTGCGTATCAAGAGCCAAAAACGAAGCTGAA
AGAAAAGAATGTGAGAAATTACTCACGCCTGAAGCGAGGAAACTCTTAGAAGAGGCTAAAGAGAGCGTTAAAGCTTATAA
AGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTGCTCACGCCTGAAGCGAAAAAACTTT
TAGAAGAAGAAGCCAAAGAAAGCGTTAAAGCTTATTTGGATTGCGTATCTCAAGCCAGAACTGAAGCTGAGAAAAAAGAA
TGCGAGAAATTACTCACGCCTGAAGCGAGGAAACTCTTAGAAGAGGCTAAAGAGAGCGTTAAAGCTTATAAAGACTGCGT
ATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAAAAATTACTCACCCCTGAAGCAAAAAAACTTTTAGAGCAAC
AAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGATAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAG
AAAAAGGTTTTAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGA
ATGCGAAAAATTACTCACCCCTGAAGCAAAAAAACTTTTAGAAGAAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCG
TATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAAAAAACTTTTAGAAGAA
GCTAAAGAGAGCGTTAAGGCTTATAAAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATT
GCTCACCCCTGAAGCGAAAAAACTTTTAGAGCAACAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGATAAAA
AAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTTTTAGCCAAAGAGAGCGTTAAGGCTTATTTGGACTGC
GTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTGCTCACGCCTGAAGCGAAAAAACTCTTAGAAGA
AGCCAAAGAGAGTCTGAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGTTTGCGAGAAAT
TACTCACCCCTGAAGCAAAAAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAAGCTTATTTAGACTGCGTTTCAAGA
GCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTGCTCACGCCTGAAGCGAGGAAATTTTTAGCGAAGCAAGTGCT
AAGCTGTTTGGAAAAAGCTAGGAATGAAGAAGAAAGAAAAGCATGTCTTAAGAATCTCCCTAAAGACTTACAAGAAAATG
TTTTAGCCAAAGAGAGTCTGAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGCGAG
AAATTGCTCACCCCTGAAGCGAAAAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGACTGCGTTTC
AAGAGCTAGGAATGAAAAAGAGAAACAGGAATGCGAAAAATTACTCACCCCTGAAGCGAGGAAATTTTTAGCAAAAGAAC
TCCAACAAAAAGATAAAGCGATCAAAGATTGCTTGAAAAACGCCGATCCTAACGACAGAGTGGCTATTATGAAGTGTTTG
GATGGTTTGAGCGATGAAGAGAAGCTCAAATATCTGCAAGAAGCTAGAGAAAAAGCCGTCTTGGATTGTTTGAAAACGGC
TAGGACTGATGAAGAAAAAAGGAAATGCCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAGGACACAAA
ATAAACAAAATCAATTGAGTAAAACAGAAAGATTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGAT
GAGCAAGCCATAGAGCAATGTTTAGAGGGCTTGAGCGATAGTGAAAGGGCGCTAATTCTAGGAATTAAACGACAAGCTGA
TGAAGTGGATCTGATTTATAGCGATCTAAGAAACCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCGTTATTGC
CAATGGATTTCAAAAATGGCGGCGATATTGCCACTATTAACGCTACTAATGTTGATGCGGACAAAATAGCTAGCGATAAT
CCTATTTATGCTTCCATAGAGCCTGATATTACCAAGCAATACGAAACAGAAAAAACCATTAAGGATAAGAATTTAGAAGC
TAAATTGGCTAAGGCTTTAGGTGGCAATAAAAAAGATGACGATAAAGAAAAAAGTAAAAAATCCACAGCAGAAGCTAAAG
CAGAAAGCAATAAGATAGACAAAGATGTCGCAGAAACTGCTAAGAATATCAGTGAAATCGCTCTTAAGAACAAAAAAGAA
AAGAGTGGGGAATTTGTAGATGAAAATGGTAATCCCATTGATGACAAAAAGAAAGCAGAAAAACAAGATGAAACAAGCCC
TGTCAAACAAGCCTTTATAGGCAAGAGTGATCCCACATTTGTTTTAGCGCAATACACCCCCATTGAAATCACTCTGACTT
CTAAAGTAGATGCCACTCTCACAGGTATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATC
TTACTAGACAAAGGCACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACACCCATTATGACACGCTTAATGAT
AGTCTTTACTAAAGCCATTACGCCTGATGGTGTGATAATACCTCTAGCAAACGCTCAAGCAGCAGGCATGTTGGGTGAAG
CAGGGGTAGATGGCTATGTGAATAATCACTTTATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTC
TTACAAACTGCGCCTATCATAGCTCTAGATAAACTCATAGGCCTTGGCAAAGGCAGAAGTGAAAGGACACCTGAATTTAA
TTACGCTTTGGGTCAAGCTATCAATGGTAGTATGCAAAGTTCAGCTCAAATGTCTAATCAAATTCTAGGGCAACTGATGA
ATATCCCCCCAAGTTTTTACAAAAACGAGGGCGATAGTATTAAGATTCTCACAATGGACGATATTGATTTTAGTGGCGTG
TATGATGTTAAAATTACCAACAAATCTGTGGTAGATGAAATCATCAAACAAAGCACTAAAACTTTGTCTAGAGAACATGA
AGAAATCACCACAAGCCCCAAAGGTGGCAATTAA

Protein sequence :
MNEENDKLETSKKTQQDSPQDLSNEEATEVNRFEDSSKESEESSDHYLDNPTETKTNFDEYELEETQTQMDSGGNETSES
SNGSLADKLFKKARKLVDNKRPFTQQKNLDEETQELNEEDDQENNGYQEETQIDLIDDETSQKTQQHSPQDLSNEEATEV
NRFEDSSKESEESSDHYLDNPTETKTNFDEDKSEEITNDSNDQEIIKGSKKKYIISGIVVAVLIVIILFSRSIFHYFMPL
EDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGN
YEECLKLIKDKKLQDQMKKTLEVYKDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLK
LINDPEIREKFRKELGLQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDL
QKELLADMSVKAYKDCVSKARNEKEKQECDKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESLK
AYKDCTSQAKTEDEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEDEKKECEKLLTPEAKKKLEEAKKSVKAYL
DCVSQAKTEDEKKECEKLLTPEARKLLEKQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVRVYLDCVSRAKNEAE
RKECEKLLTPEARKLLEEAKESVKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQARTEAEKKE
CEKLLTPEARKLLEEAKESVKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQ
KKVLAKESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEE
AKESVKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQKKVLAKESVKAYLDC
VSRARNEKEKQECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRVCEKLLTPEAKKLLEQEVKKSVKAYLDCVSR
ARNEKEKQECEKLLTPEARKFLAKQVLSCLEKARNEEERKACLKNLPKDLQENVLAKESLKAYKDCLSQARNEEERRACE
KLLTPEAKKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRVAIMKCL
DGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKRTQNKQNQLSKTERLHQASECLDNLDDPTD
EQAIEQCLEGLSDSERALILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDN
PIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEAKAESNKIDKDVAETAKNISEIALKNKKE
KSGEFVDENGNPIDDKKKAEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMI
LLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSF
LQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGV
YDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN