PAI Gene Information


Name : HP0547
Accession : BAD13935.1
PAI name : cag PAI
PAI accession : AB120421
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to H.pylori 26695 gene HP0547:cag26, J99 gene JHP0495, NCTC11638 gene cag-A
Homologs in the searched genomes :   49 hits    ( 48 protein-level,   1 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGACTAACGAAACTATTGACCAACAACCACAAACCGAAGCGGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAGGT
AGCTTTTCTTAAGCTTGATAACTCTATCACTTCATTTGATCCCGATCAAAAACCAATCGTTGATAAGAATGATAGGGATA
ACAGGCAAGCTTTTGATGAAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAATAATTTAATCAACAAAGACGCTCTCATTGATGTAGAATCTTCCACAAA
GAGCTTTCAGAAGTTTGGGGATCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAAAAAGCAGAGTTTTTG
AAATCTGCCAAACAAGCTTTTGCAGGAATTATCATAGGAAACCAGATCCGATCAGATCAAAAATTCATGGGCGTGTTTGA
TGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTACTGGTGGGGATTGGTTGGATATTTTTTTATCAT
TTATATTTCACAAAAAACAATATTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCATGTCCAACCAGATATA
GCCACTACCACCACCCACATACAAGGCTTGCCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGCGTCGCCGACATTGATCCTAATTACAAGTTCAATCAGTTATTGA
TCCACAATAACGCTTTATCTTCTGTGCTAATGGGGAGTCATAATAACATAGAACCTGAAAAAGTTTCATTATTGTATGGG
GATAATGGTGGTCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGGTAACAATGTGGCCAC
ACTCATTAATGCGCATCTTAATAACGGCAGTGGGTTAATCATAGCGGGTAATGAGGATGGGATTAAAAACCCTAGCTTCT
ATCTCTATAAAGAAGATCAACTCACAGGTTTGAAACAAGCATTGAGTCAAGAAGAGATCCAAAACAAAGTGGATTTCATG
GAATTTCTTGCACGAAACAATGCTAAACTAGATAACTTGAGCAAGAAAGAGAAAGAAAAATTCCAAACTGAGATTGAAAA
TTTCCAAAAAAACCCTAAGGCTTATTTGGACGCTCTGGGGAATGATCGCATTGCTTTTGTTTCTAAAAAAGACCCAAAAC
ATTTAGCTTTGGTTACTGAGTTTGGTAATGGGGAAGTGAGCTATACTCTCAAAGATTATGGGAAAAAACAAGATAAAGCT
TTAGATGGGGAGACAAAAACCACTCTTCAAGGTAACCTAAAATATGATGGCGTGATGTTTGTCAATTATTCTAATTTCAA
ATACACCAACGCCTCCAAGAGTCCTAATAAGGGCGTGGGTGCTACGAATGGCGTTTCCCATTTGGAAGCGAATTTTAGCA
AGGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTAATTATATAAGGCGAGATTTAGAAGATAAATTG
TGGGCTAAAGGATTGTCCCCACAAGAAGCTAGTAAGCTCATCAAAGACTTTTTGAACAGCAACAAAGAATTAGTTGGAAA
AACTTTAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAACACAGGCAATTATGATGGAGTGAAAAAAGCTCAGAAAGATC
TTGAAAAATCTATAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGCGAAAAAATTGGAGAGCAGAAACGACAACAAAAAT
AGAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCACTTATCAATCAAGAGGCTAGTAAGGAAGC
AAGAGCAGCCGCTTTCGATCCGAGTCTTAAAGGTATCAGGAGCGAATTGTCTGATAAACTTGAAAATATCAACAAGAATT
TGAAAGACTTTGGCAAATCTTTTGATGAACTCAAAAATGGCAAAAATAATGATTTCAGCAAGGCAGAAGAAACGCTAAAA
GTCCTTAAAGACTCGGTGAAAGATTTAGCCATCAATCCAGAATGGATTTCAAAAATTGAAAACCTTAATGCAGCTTTGAA
TGATTTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACACAAGCAAAAAGCGACCTTGAAAATTCTATTAAGGATG
TGATCATTAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAGGCTGTATCAGAGACTAAATTAACAGGCGATTTC
AGTAAGGTAGAGCAAGTGTTAGCCGATCTCAAAAACTTCTCAAAGGAGCAATTGGCTCAACAAACTCAAAAAAATGAAAG
TCTCAATGCTGGAAAAAAATCTGAAATATACCAATCCGTTAAGAATGGTGTGAACGGAACCCTAGTTGGTAATGGGTTAT
CTCAAGCAGAAGCCACAACTCTTTCTAAAAACTTTTCGGACATCAAGAAAGAGTTGAATGCAAAACTTTTTGGAAATTTC
AATAACAATAACAATAATGGTCTCAAAAACAGCACAGAACCCATTTATGCTAAAGTTAATAAAAAGAAAACAGGACAAGT
AGCTAGCCCTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAACTCAAAAAATTGACCAACTCAATCAAGCAGCAA
GTGGTTTGGGTGGTGTAGGGCAAGCGGGCTTCCCTTTGAAAAGGCATACTAAAGTTGATGATCTCAGTAAGGTAGGGCTT
TCAGCTAGCCCTGAACCCATTTACGCTACAATTGATTTTGATGAGGCAAATCAAGCAGGCTTCCCTTTGAGAAGAAGTGC
TGCAGTTAATAATCTCAGTAAGGTAGGGCTTTCAGCTAGCCCTGAACCCATTTACGCTACAATTGATTTTGATGAGGCAA
ATCAAGCAGGCTTCCCTTTGAGAAGAAGTGCTGCAGTTAATAATCTCAGTAAGGTAGGGCTTTCAAGGGAGCAAAAATTG
AAACAGAAGATTGACAATCTCAATCAGGCGGTATCAGAAGCTAAAGCAGGTTATTTTGGCAATCTAGAACAAACGATAGA
CAAGCTCAAAGATTCTATAAAAAACAATTCTGTGAATCTATGGGCTGAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTCGG
CGAAACTAGACAATTACGCTACTAACAGTCACACACGCATTAATAGCAATATCCAAAATGGAGCAATCAATGGAAAAGCG
ACCGGTATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTAGGAAGCGT
TCCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCA
AGTTGAACAATGCTGTAAAAGATGTTAAGTCTGGCTTTACGCAAATTTTAGCCAATGCATTTTCTACAGGATATTACTGC
TTGGCGAGGGAAAATGCGGAGCATGGAATCAAAAATGTTAATACAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence :
MTNETIDQQPQTEAAFNPQQFINNLQVAFLKLDNSITSFDPDQKPIVDKNDRDNRQAFDEISQLREEYSNKAIKNPTKKN
QYFSDFINKSNNLINKDALIDVESSTKSFQKFGDQRYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPISDDKEKAEFL
KSAKQAFAGIIIGNQIRSDQKFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFHKKQYSDVKEAINQEPVPHVQPDI
ATTTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNNIEPEKVSLLYG
DNGGPEARHDWNATVGYKDQQGNNVATLINAHLNNGSGLIIAGNEDGIKNPSFYLYKEDQLTGLKQALSQEEIQNKVDFM
EFLARNNAKLDNLSKKEKEKFQTEIENFQKNPKAYLDALGNDRIAFVSKKDPKHLALVTEFGNGEVSYTLKDYGKKQDKA
LDGETKTTLQGNLKYDGVMFVNYSNFKYTNASKSPNKGVGATNGVSHLEANFSKVAVFNLPNLNNLAITNYIRRDLEDKL
WAKGLSPQEASKLIKDFLNSNKELVGKTLNFNKAVAEAKNTGNYDGVKKAQKDLEKSIRKREHLEKEVAKKLESRNDNKN
RMEAKAQANSQKDKIFALINQEASKEARAAAFDPSLKGIRSELSDKLENINKNLKDFGKSFDELKNGKNNDFSKAEETLK
VLKDSVKDLAINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVIINQKITDKVDNLNQAVSETKLTGDF
SKVEQVLADLKNFSKEQLAQQTQKNESLNAGKKSEIYQSVKNGVNGTLVGNGLSQAEATTLSKNFSDIKKELNAKLFGNF
NNNNNNGLKNSTEPIYAKVNKKKTGQVASPEEPIYTQVAKKVTQKIDQLNQAASGLGGVGQAGFPLKRHTKVDDLSKVGL
SASPEPIYATIDFDEANQAGFPLRRSAAVNNLSKVGLSASPEPIYATIDFDEANQAGFPLRRSAAVNNLSKVGLSREQKL
KQKIDNLNQAVSEAKAGYFGNLEQTIDKLKDSIKNNSVNLWAESAKKVPASLSAKLDNYATNSHTRINSNIQNGAINGKA
TGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDVKSGFTQILANAFSTGYYC
LARENAEHGIKNVNTKGGFQKS