PAI Gene Information


Name : HP0547
Accession : BAD13908.1
PAI name : cag PAI
PAI accession : AB120420
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to H.pylori 26695 gene HP0547:cag26, J99 gene JHP0495, NCTC11638 gene cag-A
Homologs in the searched genomes :   46 hits    ( 45 protein-level,   1 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGACTAACGAAACTATTGACCAACAACCACAAACCGAAGTGGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGT
AGCTTTTCTTAAGCTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATAAGAACGATAGGGATA
ACAGGCAAGCTTTTGAGAAAATCTCGCAACTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTGCCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTGATCAACAAAGACAATCTCATTGCTGTAGATTCTTCCGTAGA
GAGCTTTCAGAAATTTGGGGATCAGCGTTACCAAATTTTCACAAGTTGGGTGTCCCTTCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAACATACCATACAACCCCCTATCCCTGATGACAAAGAAAAAGCAGAGTTTTTG
AAATCTGCCAAGCAATCTTTTGCAGGAATCATTATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGACGTGTTTGA
TGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTGCTGGTGGGGATTGGTTGGATATTTTTCTCTCAT
TTATATTTGACAAAAAACAATCTTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCATGTTCAACCAGATATA
GCCACTACCACCACCGACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGAGTCGCTGACATTGATCCTAATTACAAGTTCAATCAATTATTGA
TTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGCG
GGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGGTAACAATGTGGCTAC
AATAATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTT
ATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTAAGTCAAGAAGAGATCCAAAACAAAATAGATTTCATG
GAATTTCTTGCACAAAATAATGCTAAATTAGACAACTTGAGCGAGAAAGAGAAAGAAAAATTTCAAACTGAGATTGAATA
TTTCCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTAAAAAAGACCCAAAAC
ATTCAGCTTTAATTACTGAGTTTGGTAATGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAAAGCT
TTAGATAGGGAGAAAAATGTTACTCTTCAAGGTAACCTAAAATATGATGGCGTGATGTTTGTTGATTATTCTAATTTCAA
ATACACCAACGCCTCCAAGAATCCCAATAAGGGTGTGGGTGCTACGAATGGCGTTTCCCATTTAGACGCAGGCTTTAACA
AGGTAGCTGTCTTTAATTTGCCTGATTTAAATAATCTCGCTATCACTAGTTTCGTAAGGCGGAATTTAGAGGATAAACTA
ACCACTAAAGGATTGTCCCTACAAGAAGCTAATAAGCTTATCAAAGATTTTTTGAGCAGCAACAAAGAATTGGTTGGAAA
AGCTTTAAACTTCAATAAAGCTGTAGCTGACGCTAAAAACACAGGCAACTATGACGAGGTGAAAAAAGCTCAGAAAGATC
TTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGAGAAAAAATTGGAGAGCAAAAGCGGCAACAAAAAT
AAAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATGAGATTTTTATGTTAATCAATAAAGAGGCTAATAGGGACGC
AAGAGCAATCATTTGCGCTCAAAATCTTAAAGGCATCAGAAGGGAATTGTCTGATAAACTTGAAAATGTCAACAAGGATT
TGAAAGACTTTAGTAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAAACACTAAAA
GCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAAAGTTGAAAACCTTAATGCAGCTTTGAA
TGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAAGCGACCTTGAAAATTCCATTAAAGATG
CGATCTTCAATCAAAAGATAACGGATAAAGTTGATGATCTCAATCAAGCGGTATCAGTGGCTAAAGCAACGGGTGATTTC
AGTAGGGTAGAGCAAGCGTTAGCCGATCTCAAAAATTTCTCAAAGGAGCAATTGGCTCAACAAACTCAAAAAAATGAAAG
TTTCAATGTTGGAAAAAAATCTGAAATATATCAATCCGTTAAGAATGGTGTGAACGGAACCCTAGTCGGTAATGGATTAT
CTGGAATAGAGGCCACAGCTCTCGCCAAAAATTTTTCGGATATCAAGAAAGAATTGAATGAGAAATTATTTGGAAATTCC
AATAACAATAATAATGGACTCAAAAACAGCACAGAACCCATTTATGCTAAAGTTAATAAAAAGAAAACAGGACAAGTAGC
TAGCCATGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCGACTCAATCAAATAGCAAGTG
GTTTGGGTGGTGTAGGGCAAGCAGCGGGCTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCGA
TCAGCTAGCCCTGAACCCATTTATGCTACAATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCATGATAAAGTTGA
TGATCTCAGTAAGGTAGGGCGATCAGCTAGCCCTGAACCCATTTATGCTACAATTGATGATCTCGGCGGACCTTTCCCTT
TGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAAGGGGGCAAGAATTGGCTCAGAAAATTGACAAT
CTCAATCAGGCGGTATCAGAAGCTAAAGCAGGTTATTTTGGCAACCTAGAACAAAAGATAGACAAGCTCAAAGATTCTAC
AAAAAACAATACTGTGAATCTATGGCTTGAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTCAGCGAAATTGGACAATTACG
CTACTAACAGCCACACACGCATTAATAGCAATATCCACAATGGAGCAATCAATGAAAAAGCGACCGGTATGCTAACGCAA
AAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTAGGAAGCGTTCCTTTGTCAGAGTATGA
TAAAATTGGCTTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAGGTTTTCCACCAAGTTGAACAATGCTGTAA
AAAACGTTAAGTCTGGCTTTACGCAATTTTTAGCCAATGCATTTTCTACAGGATATTACAGCTTGGCGGGAGAAAATGCG
GAGCATGGAATCAAAAATGTTAATACAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence :
MTNETIDQQPQTEVAFNPQQFINNLQVAFLKLDNAVASFDPDQKPIVDKNDRDNRQAFEKISQLREEYSNKAIKNPAKKN
QYFSDFINKSNDLINKDNLIAVDSSVESFQKFGDQRYQIFTSWVSLQNDPSKINTRSIRNFMEHTIQPPIPDDKEKAEFL
KSAKQSFAGIIIGNQIRTDQKFMDVFDESLKERQEAEKNGEPAGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPHVQPDI
ATTTTDIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYA
GNGGFGAKHDWNATVGYKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFM
EFLAQNNAKLDNLSEKEKEKFQTEIEYFQKDSKAYLDALGNDRIAFVSKKDPKHSALITEFGNGDLSYTLKDYGKKADKA
LDREKNVTLQGNLKYDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLDAGFNKVAVFNLPDLNNLAITSFVRRNLEDKL
TTKGLSLQEANKLIKDFLSSNKELVGKALNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKN
KMEAKAQANSQKDEIFMLINKEANRDARAIICAQNLKGIRRELSDKLENVNKDLKDFSKSFDEFKNGKNKDFSKAEETLK
ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSIKDAIFNQKITDKVDDLNQAVSVAKATGDF
SRVEQALADLKNFSKEQLAQQTQKNESFNVGKKSEIYQSVKNGVNGTLVGNGLSGIEATALAKNFSDIKKELNEKLFGNS
NNNNNGLKNSTEPIYAKVNKKKTGQVASHEEPIYTQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKRHDKVDDLSKVGR
SASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGLSRGQELAQKIDN
LNQAVSEAKAGYFGNLEQKIDKLKDSTKNNTVNLWLESAKKVPASLSAKLDNYATNSHTRINSNIHNGAINEKATGMLTQ
KNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFRFSTKLNNAVKNVKSGFTQFLANAFSTGYYSLAGENA
EHGIKNVNTKGGFQKS