Name : HP0527
Accession : BAD13888.1
PAI name : cag PAI
PAI accession : AB120420
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to virB10, H.pylori 26695 gene HP0527:cag7, J99 gene JHP0476, NCTC11638 gene ORF13andORF14:cag-Y
Homologs in the searched genomes : 35 hits ( 34 protein-level, 1 DNA-level )
Publication :
-Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.
-Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.
DNA sequence : | |
ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAGCCCAACAAGATTCACCCCAAGATCTATCTAATGAAGAAGC
AACAGAAGCCAATCATTTTGAAGATCTTTTAAAAGAAGAAAGTTCAGATAATCATCTTGACAACCCCACAGAAGCTAAAA
CCCATTTTGATGAAGACAAGCTAGAAGAAACCCAAACTCAAATAGATTCTGGAGGTAATGAAACTTCAGAATCTAGCAAT
GGCAGTCTGGCAGACAAGTTATTCAAGAAAGCCAGAAAATTAGTTGATGATAAAAGACCTTTCACTCAGCAAAAGAGTTT
AGATGAAGAAGTTCAAAAACTGAACGAAGAAGACGATCAAGAAAATAATGAGTATCAAGAAAATAATGAGTATCAAGAAA
ATAATGAGTATCAAGAAAATAATGGGGATCAAGAAGAAACTCAAATGGACTTAATTGATGATGAAACTTCTAAAAAAACC
CAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCAACAGAAGCCAATCACTTTGAAGATTCTTCAAAAGAATCCAA
AGAAAGCTCAGATCATCATCTTGACAACCCCACAGAAACTAAAACCAATTTTGATGAATACGAGTCAGAAGAAATAACTA
ACGATTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGTGGCATTGTAGTCGCTGTTCTTATC
TTGATTATTTTATTTTCTAGAAGCATTTTTCATTACTTCATACCTTTGGAAGATAAAAGCTCTCGTTTTAGCAAAGACAG
GAATCTTTATGTTAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAGAACGGAATGAAAAAGGCAATA
TGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTGAATATTGCAGAAATTGAGGAC
AAAAACCCATTGAGAGCCTTTTATGAGTGTATTAGTAATGGTGGCAACTATGAAGAATGTTTGAAGCTTATCAAAGACAA
AAAACTTCAAGATCAAATGAAAAAGACTCTAGAGGCTTATAATGACTGCATCAAAAATGCTAAAACTGAAGAAGAAAGGA
TCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAAAAAGTTCAAGTGGCGCTAGAT
TGTTTGAAAAACGCTAAAACCGATGAAGAACGGAAAGAGTGCCTAAAACTCATAAATGACCCTGAGATTAGAGAGAAATT
CCGTAAGGAATTAGAGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACGCCAAAACAGAGGCTGAGAAAA
ATGAATGCTTGAAAGGCTTGTCTAAAGAAGCTATAGAAAGATTGAAACAGCAAGCGCTAGATTGTTTGAAAAACGCTAAA
ACCGATGAAGAACGAAACGAGTGCTTGAAAAATATTCCCCAAGACTTGCAAAAAGAACTACTAGCTGATATGAGCGTCAA
GGCTTATAAGGACTGCGTTTCAAAAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTGCTCACGCCTGAAGCGA
AAAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAAAAAGTGTTTGAAAGAT
CTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGTCTGAAAGCTTATAAAGACTGCACATCTCAAGCCAAAAC
TGAAGATGAGAAAAAAGAGTGTGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCCAAAGAGAGCG
TTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAAAGAAAAGAATGCGAGAAATTACTCACCCCTGAA
GCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGATGA
GAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAGCAACAAGCGCTAGATTGTTTGAAAAACG
CTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTTTTAGCCAAAGAGAGC
GTTAGGGTTTATTTGGATTGCGTATCAAGAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTACTCACGCCTGA
AGCGAGAAAGCTATTAGAAGAAGCTAAAAAAAGCGTTAAAGCTTATAAAGACTGCGTATCAAGAGCCAGGAATGAAAAAG
AGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTATTAGAAGAAGCTAAAAAAAGCGTTAAAGCTTAT
TTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAAAGAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAACT
ATTAGAAGAAGCTAAAGAGAGCGTCAAAGCTTATAAAGACTGCCTCTCCCAAGCTAGAAATGAAACTGAAAGAAAAGCTT
GCGAGAAATTACTCACCCCTGAAGCGAGAAAACTTTTAGAGAAGCAAGCACTAGATTGTTTGAAAAACGCTAAAACCGAA
GCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTTTTAGCTAAAGAAAGCGTTAAGGCTTA
CTTGGATTGTGTATCTCAAGCTAAAAACGAAGCTGAAAGAAAAGCTTGCGAGAAATTACTCACCCCTGAAGCGAAAAAAC
TTTTAGAAGAAGCTAAAGAGAGCGTCAAGGCTTACAAGGACTGCGTATCAAGAGCCAGGAATGAAAAAGAGAAACAAGAA
TGCGAGAAATTACTCACGCCTGAAGCGAGGAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTCAAGGCTTATTTAGACTG
CGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTATTAGAGA
AGCAAGCTCTAGATTGTTTGAAAAACGCTAAAACTGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTA
CAGAAAAAGGTTTTAGCCAAAGAGAGCGTTAAGGCTTATTTAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACA
AGAATGCAAGAAATTACTCACCCCTGAAGCGAAAAAACTATTAGAAGAAGCTAAAGAGAGCCTTAAAGCTTATAAGGACT
GCCTCTCTCAAGCTAGAAATGAAACTGAAAGGAGAGCCTGCGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAG
CAAGAAGTTAAGAAGAGTGTTAAGGCTTATTTGGACTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAACAAGAATGCGA
GAAATTACTCACGCCTGAAGCAAGGAAATTTTTAGAGAAGCAAGCATTAAGTTGTTTGGAAAAAGCTAGAAATGAAGAAG
AAAGAAAAGCATGTCTTAAAAATATCCCTAAAGATTTACAGAAAAATGTTTTAGCTAAAGAGAGCCTTAAAGCTTATAAG
GACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTACT
AGAACAAGAAGTTAAAAAGAGCGTCAAGGCTTATTTGGATTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAACAAGAAT
GCGAGAAATTACTCACGCCTGAAGCGAGGAAATTTTTAGAGAAAGAACTCCAACAAAAAGATAAAGCGATAAAAGATTGC
TTGAAGAACGCCGATCCTAACGACAGAGCGGCTATTATGAAGTGTTTGGATGGTTTGAGCGATGAAGAGAAGCTCAAATA
CCTGCAAGAAGCTAGAGAAAAGGCTGTTGCGGATTGTTTGGCTATGGCTAAAACCGATGAAGAAAAAAGGAAATGCCAAA
ACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAGGGCACAGAACAAACAAAATCAATTGAGTAAAACAGAAAGG
TTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGATCAAGAAGCCATAGAGCAATGTTTAGAGGGATT
GAGCGATAGCGAAAGGGCGCTAATTCTAGGAATCAAACGACAAGCTGATGAAGTGGATCGGATTTATAGCGATCTAAGAA
GCCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCATTGTTGCCAATGGATTTCAAAAATGGTGGCGATATTGCC
ACTATTAACGCCACTAATGTTGATGCGGACAAAATAGCTAGCGATAATCCTATTTATGCTTCCATAGAGCCTGATATTAC
TAAGCAATACGAAACAGAAAAAACCATTAAGGATAAGAATTTAGAAGCTAAATTGGCTAAGGCTTTAGGTGGTAATAAAA
AAGATGACGATAAAGAAAAAAGTGAAAAATCCACAGCAAAAGCTAAAGCAGAAAGCAATAAGATAGACAAAGATGTCGCA
GAAACTGCCAAAAATATCAGCGAAATCGCTCTTAAGAACAAAAAAGAAAAGAGTGGGGATTTTGTAGATGAAAATGGTAA
TCCCATTGACGATAAAAAGAAAGAAGAAAAACAAGATGAAACAAGCCCTGTCAAACAGGCCTTTATAGGCAAGAGTGATC
CCACATTTGTTTTAGCGCAATACACCCCTATTGAAATCACTCTGACTTCTAAAGTAGATGCCACTCTCACAGGTATAGTG
AGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATCTTACTAGACAAAGGCACTAAGGTGTATGGGAA
TTATCAAAGCGTGAAAGGTGGCACACCCATTATGACTCGTTTAATGATAGTCTTTACTAAAGCCATTACGCCTGATGGTG
TGATAATACCTCTAGCAAACGCTCAAGCAGCAGGCATGTTGGGTGAAGCAGGGGTAGATGGCTATGTGAATAATCACTTC
ATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTCTTGCAAACTGCGCCTATCATAGCTCTAGATAA
ACTCATAGGCCTTGGCAAAGGTAGAAGTGAAAGGACACCTGAGTTTAATTACGCTTTGGGTCAAGCTATCAATGGCAGTA
TGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGGGCAACTGATGAATATCCCCCCAAGTTTTTACAAAAACGAGGGC
GATAGTATTAAGATTCTCACAATGGACGATATTGATTTTAGTGGCGTGTATGATGTTAAAATTACCAACAAATCTGTGGT
AGATGAAATCATCAAACAAAGCACCAAAACTTTGTCTAGAGAACATGAAGAAATCACCACAAGCCCCAAAGGTGGCAATT
AA
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Protein sequence : | |
MNEENDKLETSKKAQQDSPQDLSNEEATEANHFEDLLKEESSDNHLDNPTEAKTHFDEDKLEETQTQIDSGGNETSESSN
GSLADKLFKKARKLVDDKRPFTQQKSLDEEVQKLNEEDDQENNEYQENNEYQENNEYQENNGDQEETQMDLIDDETSKKT
QQHSPQDLSNEEATEANHFEDSSKESKESSDHHLDNPTETKTNFDEYESEEITNDSNDQEIIKGSKKKYIIGGIVVAVLI
LIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIED
KNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALD
CLKNAKTDEERKECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAK
TDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKD
LPKDLQSDILAKESLKAYKDCTSQAKTEDEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAERKECEKLLTPE
AKKKLEEAKKSVKAYLDCVSQAKTEDEKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKES
VRVYLDCVSRAKNEAERKECEKLLTPEARKLLEEAKKSVKAYKDCVSRARNEKEKKECEKLLTPEARKLLEEAKKSVKAY
LDCVSQAKTEAERKECEKLLTPEAKKLLEEAKESVKAYKDCLSQARNETERKACEKLLTPEARKLLEKQALDCLKNAKTE
AEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSQAKNEAERKACEKLLTPEAKKLLEEAKESVKAYKDCVSRARNEKEKQE
CEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEAKKLLEKQALDCLKNAKTEAEKKRCVKDLPKDL
QKKVLAKESVKAYLDCVSRARNEKEKQECKKLLTPEAKKLLEEAKESLKAYKDCLSQARNETERRACEKLLTPEAKKLLE
QEVKKSVKAYLDCVSKARNEKEKQECEKLLTPEARKFLEKQALSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYK
DCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSKARNEKEKQECEKLLTPEARKFLEKELQQKDKAIKDC
LKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVADCLAMAKTDEEKRKCQNLYSDLIQEIQNKRAQNKQNQLSKTER
LHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDRIYSDLRSRKTFDNMAAKGYPLLPMDFKNGGDIA
TINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSEKSTAKAKAESNKIDKDVA
ETAKNISEIALKNKKEKSGDFVDENGNPIDDKKKEEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIV
SGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHF
MKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEG
DSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN
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