PAI Gene Information


Name : HP0528
Accession : BAD13780.1
PAI name : cag PAI
PAI accession : AB120416
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to virB9, H.pylori 26695 gene HP0528:cag8, J99 gene JHP0477, NCTC11638 gene ORF15:cag-X
Homologs in the searched genomes :   44 hits    ( 44 protein-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGGAGCAGGCATTTTTTAAAAAAATTGTTGGCTGTTTCTGTCTTGGTTGTTTATTTTTATCTAATGTAATAGAAGCAGC
ACCTGACATTAAAAATTTTAATCGTGGTAGGGTGAAAGTGGTGAATAAGAAGATTGCTTATTTGGGAGATGAAAAACCTA
TTACGATTTGGACTTCATTAGACAATGTTACTGTGATCCAACTTGAAAAAGATGAAACTATTTCTTACATCACAACAGGT
TTCAATAAAGGTTGGAGTATTGTGCCTAATTCTAATCATATATTCATTCAACCTAAATCGGTAAAAAGTAATCTCATGTT
TGAAAAAGAAGCAGTGAATTTTGCCCTAATGACAAGAGATTATCAAGAATTTTTAAAAACAAAAAAACTTATCGTAGATG
CGCCTGACCCTAAAGAATTAGAAGAACAAAAAAAAGCTCTAGAAAAAGAAAAAGAAGCTAAAGAACAGGCGCAAAAAGCG
CAAAAAGATAAAAGAGAAAAAAGAAAGGAAGAGCGTGCAAAAAATAGAGCCAATTTAGAAAATCTCACTAACGCTATGAG
TAACCCACAAAATTTGAGCAATAACAAAAATCTTAGTGAATTTATCAAGCAACAACGAGAAAATGAATTAGATCAAATGG
AACGACTAGAGGACATGCAAGAACAGGCTCAAGCTAATGCACTCAAACAAATTGAAGAACTCAACAAAAAACAAGCTGAA
GAAGCAGTGAAACAAAGAGCTAAGGATAAAATCAATATTAAGACAGATAAGTCTCAAAAAAGCCCTGAGGATAACTCCAT
AGAATTATCTCCTAGCGATAGCGCTTGGAGAACTAATCTTGTTGTGCGGACTAATAAAGCCTTGTATCAATTCATTTTGA
GAATAGCTCAAAAAGACAATTTTGCTTCGGCGTATCTAACAGTCAAATTAGAATACCCACAAAGACACGAAGTCTCTAGC
GTTATTGAAGAGGAGTTAAGAAAGAGAGAAGAAGCAAAAAGGCAGAGAGAATTGATCAAGCAAGAAAATCTTAACACCAC
AGCCTACATCAATAGAGTAATGATGGCGAGCAATGAACAGATTATCAACAAAGAAAAAATAAGAGAAGAAAAACAAAAAA
TTATTTTAGATCAAAAAAAGGCGCTAGAGACTCAATATGTGCATAATGCGTTAAAAAGAAACCCTGTGCCTAGAAACTAC
AATTACTACCAAGCACCTGAAAAACGCTCTAAGCATATTATGCCCTCTGAAATTTTTGATGATGGCACATTCACTTATTT
TGGTTTCAAAAACATCACTCTCCAACCTGCTATTTTTGTGGTTCAGCCTGATGGGAAATTAAGCATGACTGATGCTGCTA
TTGATCCTAATATGACCAATTCAGGATTGAGATGGTATAGAGTTAATGAAATTGCAGAAAAGTTTAAGCTCATTAAAGAC
AAAGCCCTTGTAACAGTAATAAATAAAGGCTATGGGAAAAATCCATTGACAAAAAATTACAATATCAAAAACTATGGTGA
ATTGGAGCGTGTGATTAAAAAGCTCCCTCTTGTCAGAGATAAATAA

Protein sequence :
MEQAFFKKIVGCFCLGCLFLSNVIEAAPDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTG
FNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKA
QKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAE
EAVKQRAKDKINIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSS
VIEEELRKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQKKALETQYVHNALKRNPVPRNY
NYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKD
KALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK