Name : tnpB
Accession : BAA82202.1
PAI name : Type-II SCCmec
PAI accession : D86934
Strain : Staphylococcus aureus 04-02981
Virulence or Resistance: Not determined
Product : transposaseB
Function : -
Note : ORF N046
Homologs in the searched genomes : 77 hits ( 75 protein-level, 2 DNA-level )
Publication :
-Hiramatsu,K., Asada,K., Suzuki,E., Okonogi,K. and Yokota,T., "Molecular cloning and nucleotide sequence determination of the regulator region of mecA gene in methicillin-resistant Staphylococcus aureus (MRSA)", FEBS Lett. 298 (2-3), 133-136 (1992) PUBMED 1544435.
-Ito,T., Asada,K., Katayama,Y. and Hiramatsu,K., "Direct Submission", Submitted (07-AUG-1996) Contact:Teruyo Ito Juntendo University, Faculty of Medicine, Department of Bacteriology; 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
-Ito,T., Katayama,Y. and Hiramatsu,K., "Cloning and nucleotide sequence determination of the entire mec DNA of pre-methicillin-resistant Staphylococcus aureus N315", Antimicrob. Agents Chemother. 43 (6), 1449-1458 (1999) PUBMED 10348769.
-Ito,T., Katayama,Y., Asada,K., Mori,N., Tsutsumimoto,K., Tiensasitorn,C. and Hiramatsu,K., "Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus", Antimicrob. Agents Chemother. 45 (5), 1323-1336 (2001) PUBMED 11302791 REMARK Erratum:[Antimicrob Agents Chemother 2001 Dec;45(12):3677].
-Ito,T., Okuma,K., Ma,X.X., Yuzawa,H. and Hiramatsu,K., "Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC", Drug Resist. Updat. 6 (1), 41-52 (2003) PUBMED 12654286.
| DNA sequence : | |
ATGAATGCTTCTAGTAAAAGGAAAATTATTAGTCAGAGTGAGATTAGCAAAAAAATAGCTGTAATGAATGAAGAAATGCA
GGGGTTTTGGGCTAATAATAGTTGGGATATAAGAAAATGTCCACATCCTTCTGCCATAGAATTAAGTAAGAATCCTGCTT
TAAGGAATCGTTGGGTTCGTTTTGAACGTGTTAAAAATCTGTGGTTAAGAACAGAATTGAAATATTTTTATTTTTACCAT
TTAAACAATGGAATATGGAATGCAAAAACTGTCTGGATTAGAAAAGGAACAGTAATTAATAAAATGTTAGATTTCTTAGA
TTTAAAGTATCCTAGCATTACTTCAATTACTGAAGTTCCTATTGAAAAAGCAATGACGGAGTATAGAACTTATTTGACAA
AACGGGGTGTTAGAATTACCACTACTAATTATAAGATTACTGCTAATCAAGAAAAAACACCTGTAAAAGCTAATTCCTAC
TATGTTACTAATCTAAAACAATTTATGGAGTTTTATGAGAACTTTTATTTTGATGGAGAGGAGTGGGATAAAGACGTTTG
GGATAGACGTAACTTACCTTTGCCAGATGATAAGGTTAACCCAACACAATATGAATATACAATTAACTTTAAAGGGTTTC
GGAATACATATTTTAAACAACTTGTAAAAAGATATTGTAAGTTGAGATTGAACGTGGATAGCTTTTCCTATGTAAGTGAT
ATTGCCCAAAGACTTAAAGAGTTCTTTAATTTTCTGGACATGAAATTTAAACAAGTTCAGAGAGTACACCAATTAACGAG
AGTGGAAATTGAAGCATATTTAAGTGAACTAAACATGATGGGAATAAAACCTAGTACAATAACTGGGAGGATCTCTATAT
TGGAAGGACTATTTAGTACCCTTCTTAGGCTAGAATGGGATGATGTTCCTTCCAAAATATTAATTTATTCTGAGGACTAT
CCGAAAATACCAAGAGCAAAACCACGCTTTATAGATGAATTCGTCCTAGAGCAATTGAACAGTCATCTTGATAAATTACC
CGAATATATAGCTACGATGACTATGATTGTTCAAGAATGTGGAATGAGGATAAGTGAATTGTGCACCTTGAAAAAAGGCT
GTCTATTAGAGGACAAAGATGGAGATTTCTTTTTAAAGTATTATCAATGGAAAATGAAAAAGGAGCATATAGTTCCAATA
TCTAAAGAGGTAGCTTTACTTATTAAAGTTCGGGAAGATAAAGTTTCAGAGGAATTTCCAGATAGTGAATACCTCTTTCC
AAGAAAAGATGGATCGCCATTAAAACAAGAAACATTTAGAGGTGAGTTAAATAAATTAGCTTATGAGCAAAATATAGTGG
ATAAATCAGGTGAGATTTATAGATTCCATGCCCATGCCTTTCGCCATACAGTAGGAACAAGAATGATTAACAACGGGATG
CCCCAGCATATTGTGCAGAAATTTTTGGGGCATGAAAGCCCAGAAATGACAAGCAGATACGCTCATATCTTTGATGAAAC
TCTAAAAAATGAATTTACTAAATTTCAGGAAAAACTGGTTACCAATAATGGAGATGTGCTTGATCTAGATGAAGATAATG
AAGTCGATGATGTAGAGCTTCAATGGTTCAAGAAAAATATAAATGCACAAGTGCTTCCAAATGGTTATTGTAGATTGCCA
GTAGTAGCAGGTGGTTGTCCACATGCGAATGCATGCTTAGATTGCACTCACTTCTGTACCAGTAAGCAATTCTTACCACA
GCACGAAGAACAGTTAGAGCGTACAGAAGAGTTATTAGCCATAGCTAAGGATAAACAATGGCAAAGACAAGTAGAGACTA
ATAGCCGTGTTAAAGAGCGTTTAGAACAAATCATTGGAAGTTTGACGGGGTAA
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| Protein sequence : | |
MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPSAIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYH
LNNGIWNAKTVWIRKGTVINKMLDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYFKQLVKRYCKLRLNVDSFSYVSD
IAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSELNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDY
PKIPRAKPRFIDEFVLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKMKKEHIVPI
SKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQNIVDKSGEIYRFHAHAFRHTVGTRMINNGM
PQHIVQKFLGHESPEMTSRYAHIFDETLKNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLP
VVAGGCPHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQIIGSLTG
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