PAI Gene Information


Name : aadA7
Accession : AGF35062.1
PAI name : SGI1
PAI accession : JX089583
Strain : Proteus mirabilis BB2000
Virulence or Resistance: Resistance
Product : aminoglycoside adenyltransferase
Function : -
Note : confers resistance to streptomycin and spectinomycin
Homologs in the searched genomes :   112 hits    ( 112 protein-level )  
Publication :
    -Siebor,E. and Neuwirth,C., "Emergence of Salmonella genomic island 1 (SGI1) among Proteus mirabilis clinical isolates in Dijon, France", J. Antimicrob. Chemother. 68 (8), 1750-1756 (2013) PUBMED 23580563.

    -Siebor,E. and Neuwirth,C., "Direct Submission", Submitted (22-MAY-2012) Bacteriology, Laboratory of Bacteriology University Hospital Dijon, Rue Angelique Ducoudray, Dijon 21070, France.


DNA sequence :
ATGAGTGAAAAAGTGCCCGCCGAGATTTCGGTGCAACTATCACAAGCACTCAACGTCATCGGGCGCCACTTGGAGTCGAC
GTTGCTGGCCGTGCATTTGTACGGCTCCGCACTGGATGGCGGATTGAAACCGTACAGTGATATTGATTTGCTGGTGACTG
TAGCTGCACCGCTCAATGATGCCGTGCGGCAAGCCCTGCTCGTCGATCTCTTGGAGGTTTCAGCTTCCCCTGGCCAAAAC
AAGGCACTCCGCGCCTTGGAAGTGACCATCGTCGTGCACAGTGACATCGTACCTTGGCGTTATCCGGCCAGGCGGGAACT
GCAGTTCGGAGAGTGGCAGCGCAAAGACATCCTTGCGGGCATCTTCGAGCCCGCCACAACCGATTCTGACTTGGCGATTC
TGCTAACAAAGGCAAAGCAACATAGCGTCGTCTTGGCAGGTTCAGCAGCGAAGGATCTCTTCAGCTCAGTCCCAGAAAGC
GATCTATTCAAGGCACTGGCCGATACTCTGAAGCTATGGAACTCGCCGCCAGATTGGGCGGGCGATGAGCGGAATGTAGT
GCTTACTTTGTCTCGTATCTGGTACACCGCAGCAACCGGCAAGATCGCGCCAAAGGATGTTGCTGCCACTTGGGCAATGG
CACGCTTGCCAGCTCAACATCAGCCCATCCTGTTGAATGCCAAGCGGGCTTATCTTGGGCAAGAAGAAGATTATTTGCCC
GCTCGTGCGGATCAGGTGGCGGCGCTCATTAAATTCGTGAAGTATGAAGCAGTTAAACTGCTTGGTGCCAGCCAATGA

Protein sequence :
MSEKVPAEISVQLSQALNVIGRHLESTLLAVHLYGSALDGGLKPYSDIDLLVTVAAPLNDAVRQALLVDLLEVSASPGQN
KALRALEVTIVVHSDIVPWRYPARRELQFGEWQRKDILAGIFEPATTDSDLAILLTKAKQHSVVLAGSAAKDLFSSVPES
DLFKALADTLKLWNSPPDWAGDERNVVLTLSRIWYTAATGKIAPKDVAATWAMARLPAQHQPILLNAKRAYLGQEEDYLP
ARADQVAALIKFVKYEAVKLLGASQ