Name : dfrA1
Accession : AGF34987.1
PAI name : SGI1
PAI accession : JX089581
Strain : Proteus mirabilis BB2000
Virulence or Resistance: Resistance
Product : DfrA1 dihydrofolate reductase
Function : -
Note : confers resistance to trimethoprim
Homologs in the searched genomes : 17 hits ( 17 protein-level )
Publication :
-Siebor,E. and Neuwirth,C., "Emergence of Salmonella genomic island 1 (SGI1) among Proteus mirabilis clinical isolates in Dijon, France", J. Antimicrob. Chemother. 68 (8), 1750-1756 (2013) PUBMED 23580563.
-Siebor,E. and Neuwirth,C., "Direct Submission", Submitted (21-MAY-2012) Bacteriology, Laboratory of Bacteriology University Hospital Dijon, Rue Angelique Ducoudray, Dijon 21070, France.
| DNA sequence : | |
GTGAAACTATCACTAATGGTAGCTATATCGAAGAATGGAGTTATCGGGAATGGCCCTGATATTCCATGGAGTGCCAAAGG
TGAACAGCTCCTGTTTAAAGCTATTACCTATAACCAATGGCTGTTGGTTGGACGCAAGACTTTTGAATCAATGGGAGCAT
TACCCAACCGAAAGTATGCGGTCGTAACACGTTCAAGTTTTACATCTGACAATGAGAACGTATTGATCTTTCCATCAATT
AAAGATGCTTTAACCAACCTAAAGAAAATAACGGATCATGTCATTGTTTCAGGTGGTGGGGAGATATACAAAAGCCTGAT
CGATCAAGTAGATACACTACATATATCTACAATAGACATCGAGCCGGAAGGTGATGTTTACTTTCCTGAAATCCCCAGCA
ATTTTAGGCCAGTTTTTACCCAAGACTTCGCCTCTAACATAAATTATAGTTACCAAATCTGGCAAAAGGGTTAA
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| Protein sequence : | |
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSI
KDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG
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