PAI Gene Information


Name : dfrA5
Accession : AFG30110.1
PAI name : PAGI-2
PAI accession : JN559393
Strain : Pseudomonas aeruginosa B136-33
Virulence or Resistance: Resistance
Product : dihydrofolate reductase
Function : -
Note : -
Homologs in the searched genomes :   30 hits    ( 30 protein-level )  
Publication :
    -Martinez,E., Marquez,C., Ingold,A., Merlino,J., Djordjevic,S.P., Stokes,H.W. and Roy Chowdhury,P., "Diverse Mobilized Class 1 Integrons Are Common in the Chromosomes of Pathogenic Pseudomonas aeruginosa Clinical Isolates", Antimicrob. Agents Chemother. 56 (4), 2169-2172 (2012) PUBMED 22271862.

    -Martinez,E., Marquez,C., Ingold,A., Merlino,J., Djordjevic,S.P., Stokes,H.W. and Roy Chowdhury,P., "Direct Submission", Submitted (04-AUG-2011) The ithree Institute, University of Technology, Sydney, Harris and Thomas St, Sydney, NSW 2007, Australia.


DNA sequence :
ATGGCTGCAAAAGCGAAAAACGGAGTGATTGGTTGCGGTCCACACATACCCTGGTCCGCGAAAGGAGAGCAGCTACTCTT
TAAAGCCTTGACGTACAACCAGTGGCTTTTGGTGGGCCGCAAGACGTTCGAATCTATGGGAGCACTCCCTAATAGGAAAT
ACGCGGTCGTTACTCGCTCAGCCTGGACGGCCGATAATGACAACGTAATAGTATTCCCGTCGATCGAAGAGGCCATGTAC
GGGCTGGCTGAACTCACCGATCACGTTATAGTGTCTGGTGGCGGGGAGATTTACAGAGAAACATTGCCCATGGCCTCTAC
GCTCCATATATCGACGATTGATATTGAGCCGGAAGGAGATGTTTTCTTTCCGAATATTCCCAATACCTTCGAAGTTGTTT
TTGAGCAACACTTTAGCTCAAACATTAACTATTGCTATCAAATTTGGCAAAAGGGTTAA

Protein sequence :
MAAKAKNGVIGCGPHIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYAVVTRSAWTADNDNVIVFPSIEEAMY
GLAELTDHVIVSGGGEIYRETLPMASTLHISTIDIEPEGDVFFPNIPNTFEVVFEQHFSSNINYCYQIWQKG