Name : oxa23
Accession : AEO37447.1
PAI name : AbaR4
PAI accession : JN107991_R1
Strain : Acinetobacter baumannii 1656-2
Virulence or Resistance: Resistance
Product : class D beta-lactamase OXA-23
Function : -
Note : confers resistance to carbapenems
Homologs in the searched genomes : 38 hits ( 38 protein-level )
Publication :
-Hamidian,M. and Hall,R.M., "AbaR4 replaces AbaR3 in a carbapenem-resistant Acinetobacter baumannii isolate belonging to global clone 1 from an Australian hospital", J. Antimicrob. Chemother. 66 (11), 2484-2491 (2011) PUBMED 21873287.
-Hamidian,M. and Hall,R.M., "Direct Submission", Submitted (10-JUN-2011) The University of Sydney, School of Molecular Biosciences, Molecular Bioscience Building G08, Sydney, NSW 2006, Australia.
| DNA sequence : | |
ATGAATAAATATTTTACTTGCTATGTGGTTGCTTCTCTTTTTCTTTCTGGTTGTACGGTTCAGCATAATTTAATAAATGA
AACCCCGAGTCAGATTGTTCAAGGACATAATCAGGTGATTCATCAATACTTTGATGAAAAAAACACCTCAGGTGTGCTGG
TTATTCAAACAGATAAAAAAATTAATCTATATGGTAATGCTCTAAGCCGCGCAAATACAGAATATGTGCCAGCCTCTACA
TTTAAAATGTTGAATGCCCTGATCGGATTGGAGAACCAGAAAACGGATATTAATGAAATATTTAAATGGAAGGGCGAGAA
AAGGTCATTTACCGCTTGGGAAAAAGACATGACACTAGGAGAAGCCATGAAGCTTTCTGCAGTCCCAGTCTATCAGGAAC
TTGCGCGACGTATCGGTCTTGATCTCATGCAAAAAGAAGTAAAACGTATTGGTTTCGGTAATGCTGAAATTGGACAGCAG
GTTGATAATTTCTGGTTGGTAGGACCATTAAAGGTTACGCCTATTCAAGAGGTAGAGTTTGTTTCCCAATTAGCACATAC
ACAGCTTCCATTTAGTGAAAAAGTGCAGGCTAATGTAAAAAATATGCTTCTTTTAGAAGAGAGTAATGGCTACAAAATTT
TTGGAAAGACTGGTTGGGCAATGGATATAAAACCACAAGTGGGCTGGTTGACCGGCTGGGTTGAGCAGCCAGATGGAAAA
ATTGTCGCTTTTGCATTAAATATGGAAATGCGGTCAGAAATGCCGGCATCTATACGTAATGAATTATTGATGAAATCATT
AAAACAGCTGAATATTATTTAA
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| Protein sequence : | |
MNKYFTCYVVASLFLSGCTVQHNLINETPSQIVQGHNQVIHQYFDEKNTSGVLVIQTDKKINLYGNALSRANTEYVPAST
FKMLNALIGLENQKTDINEIFKWKGEKRSFTAWEKDMTLGEAMKLSAVPVYQELARRIGLDLMQKEVKRIGFGNAEIGQQ
VDNFWLVGPLKVTPIQEVEFVSQLAHTQLPFSEKVQANVKNMLLLEESNGYKIFGKTGWAMDIKPQVGWLTGWVEQPDGK
IVAFALNMEMRSEMPASIRNELLMKSLKQLNII
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