PAI Gene Information


Name : unnamed
Accession : AEL12695.1
PAI name : AbaR21
PAI accession : JN121384
Strain : Acinetobacter baumannii 1656-2
Virulence or Resistance: Resistance
Product : DfrA5
Function : -
Note : trimethoprim resistant dihydrofolate reductase; dfrA5
Homologs in the searched genomes :   29 hits    ( 29 protein-level )  
Publication :
    -Hall,R.M., Post,V. and Nigro,S.J., "Direct Submission", Submitted (14-JUN-2011) School of Molecular Bioscience, University of Sydney, Biochemistry and Microbiology Bldg G08, Sydney, NSW 2006, Australia.

    -Nigro,S.J., Post,V. and Hall,R.M., "The multiresistant Acinetobacter baumannii European clone I type strain RUH875 (A297) carries a genomic antibiotic resistance island AbaR21, plasmid pRAY and a cluster containing ISAba1-sul2-CR2-strB-strA", J. Antimicrob. Chemother. 66 (8), 1928-1930 (2011) PUBMED 21642651.


DNA sequence :
GTGAAAGTATCATTAATGGCTGCAAAAGCGAAAAACGGAGTGATTGGTTGCGGTCCACACATACCCTGGTCCGCGAAAGG
AGAGCAGCTACTCTTTAAAGCCTTGACGTACAACCAGTGGCTTTTGGTGGGCCGCAAGACGTTCGAATCTATGGGAGCAC
TCCCTAATAGGAAATACGCGGTCGTTACTCGCTCAGCCTGGACGGCCGATAATGACAACGTAATAGTATTCCCGTCGATC
GAAGAGGCCATGTACGGGCTGGCTGAACTCACCGATCACGTTATAGTGTCTGGTGGCGGGGAGATTTACAGAGAAACATT
GCCCATGGCCTCTACGCTCCATATATCGACGATTGATATTGAGCCGGAAGGAGATGTTTTCTTTCCGAATATTCCCAATA
CCTTCGAAGTTGTTTTTGAGCAACACTTTAGCTCAAACATTAACTATTGCTATCAAATTTGGCAAAAGGGTTAA

Protein sequence :
MKVSLMAAKAKNGVIGCGPHIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYAVVTRSAWTADNDNVIVFPSI
EEAMYGLAELTDHVIVSGGGEIYRETLPMASTLHISTIDIEPEGDVFFPNIPNTFEVVFEQHFSSNINYCYQIWQKG