PAI Gene Information


Name : topA
Accession : ADI24145.1
PAI name : AbaR1
PAI accession : HM357806
Strain : Acinetobacter baumannii 1656-2
Virulence or Resistance: Not determined
Product : DNA topoisomerase I
Function : -
Note : -
Homologs in the searched genomes :   13 hits    ( 13 protein-level )  
Publication :
    -Krizova,L. and Nemec,A., "A 63 kb genomic resistance island found in a multidrug-resistant Acinetobacter baumannii isolate of European clone I from 1977", J. Antimicrob. Chemother. 65 (9), 1915-1918 (2010) PUBMED 20558468.

    -Krizova,L. and Nemec,A., "Direct Submission", Submitted (26-MAY-2010) Laboratory of Bacterial Genetics, National Institute of Public Health, Srobarova 48, Prague 10 100 42, Czech Republic.


DNA sequence :
ATGACCACATTGGTAATCGTAGAATCGCCGGGCAAGGTGAAGAAGATCAGCGCCTTGCTGGGAGCGGGCTACAAGGTTGT
GGCGAGCGTTGGACACGTCCGCGACTTGCCGCCGAAGGAACTAGGGATAGAGCCGCCGGACTTCCGCCCGCACTATCAAC
CGACCGAGCGCGGGCGCGACGTGTTAGCCCGGCTGAAAAAGGACGTGGCCGCCGCCGACCGTATTTTGCTGGCGACCGAC
CCCGACCGTGAAGGCGAGGCAATCGCGTGGCACTTGGCCGACGCGCTCAAGCTGCGCGATCCGCAGCGCATCACCTTTAC
GGCCATCACGAAAGATAAGGTTCAAGCCGCCGTCGCCGCGCCGCGTCGCATCGACATGAACCGCGTGCGGTCGCAAGAGG
CTCGCCGTGCGCTCGACCGCATCGTGGGCTACCGGGTAAGCCCGGCCCTGTCAGATCGGGCCGGACAGCCGCTTTCAGCG
GGGCGCGTGCAGTCTCCGGCGGTGCGCCTTGTGGTGGACCGCGAGCGCGAGATTGCGAGCTTCAAAGTCACCGAGCATTA
CGGCGCGGAACTGACATTCGACAACGGCGACGGCACGGCATGGCGGGCCGTTTGGGACACCAAACCACACATGGCCGAGG
GCGAAAGCTACATCATGGACGACGCGCTTGCGCTGCGCGTGGCGGCAGTGCGCCACGTCACGGTCGCCGAGGTCGCCGAC
ACCGAGAAGGGCCGCGCACCGGCTGCGCCGTTCACAACGTCCACGTTGCAGCAGGCCGCCGGGCAGCGGTTGAAGCTGCG
ACCGAAAAAGACGATGGAGCTTGCGCAACGCCTCTATGAACAAGGCGCAATCACCTATCACCGCACCGACGCGCCCAACA
TGGACGACGCCGGTATGGAGGACATTGCAGCCTATGCCCGCAGCGCGGGCTTGCCGCTGGCCGAGAAGCCCCGGCGCTGG
AAAGCCAAGGAAGGCGCGCAGGAGGGCCACGAAGCGATACGGCCCACCCACGCGGCGGACCTTGAGGCGGGGGAAACAGA
CGATGAAAAGGCGCTCTATCGCCTTATCTGGCAACGTGCCGTCGCCTCGCAGCTTGCCGACGCGATTTATGCCGTGCGAT
CCGTGCGCCTCGCCGGGGATGCGGAAGGGCTGGCCGTGGCGTTCACGGCGACAGGCCGCACCCTGCAATCGCCGGGATGG
ATGGCCGTCTATGCGGCGGATGCCGACGACAGCGACGACGAGGGCGAAGCGTCGAATAACCCGATTCCGGCACTGGCCGA
GGGCGCGGGCTTAACCGCATCGAGCGGGCGACTTTTGACGAAGCACACGAAGCCGCCCACGCGCTTTACCGAGGCAACGC
TTGTCAAGGAAATGGAGCGGCTAGGCATCGGACGGCCCAGCACCTACGCGGCGATCATCGAGAACATCACGGGTCGCGGC
TACGTCATAGAAGGGCAGAAAGGCTATCTCACGCCGTCACCCATCGGCGAGACGATCCGCGATGCGCTTGTAGGCCGGTT
CCGCTTCGCCGAACTCGATTACACGCGGGGCCTTGAGGACGAGCTAGACCAAATCGCGGAGGCGAAGGCCGACTATCAGG
GAGTCATTTCCGCCGCATGGTCCGCGCTCGACGACGAGCTAGGCAAGCTGGACAGCGCCGGAATCGCCGCCGCCCATCCT
TGCCCGGCGTGCGGCAAGGCCCTGCATCGCCGGAAGGGGCAATATGGCTTCTTTTGGTCCTGCACCGGCTATCCCGAGTG
CAAGACCTCGCTCCCCGACGACAAGGGCAAGCCCGGCCAGCGGAAGGCCCCGCCGCCGTCTACCGGCTTCCAGTGCCCGA
AGTGCGGCAAAGAGCTTGCCCGCCGTCAGGGCGTCAGCAAGCCGAAGAAGAAGGGCATGAAGGGGCGGCCCTACGATTTC
TATAGCTGCACGGGCTACCCGAAGTGTGACGCCAGCTATCAGACCGGGCCGGACGGAAAGCCGGTTTTTGAGGGGGCAGG
ACAGCAAGCCGCCGAGTAG

Protein sequence :
MTTLVIVESPGKVKKISALLGAGYKVVASVGHVRDLPPKELGIEPPDFRPHYQPTERGRDVLARLKKDVAAADRILLATD
PDREGEAIAWHLADALKLRDPQRITFTAITKDKVQAAVAAPRRIDMNRVRSQEARRALDRIVGYRVSPALSDRAGQPLSA
GRVQSPAVRLVVDREREIASFKVTEHYGAELTFDNGDGTAWRAVWDTKPHMAEGESYIMDDALALRVAAVRHVTVAEVAD
TEKGRAPAAPFTTSTLQQAAGQRLKLRPKKTMELAQRLYEQGAITYHRTDAPNMDDAGMEDIAAYARSAGLPLAEKPRRW
KAKEGAQEGHEAIRPTHAADLEAGETDDEKALYRLIWQRAVASQLADAIYAVRSVRLAGDAEGLAVAFTATGRTLQSPGW
MAVYAADADDSDDEGEASNNPIPALAEGAGLTASSGRLLTKHTKPPTRFTEATLVKEMERLGIGRPSTYAAIIENITGRG
YVIEGQKGYLTPSPIGETIRDALVGRFRFAELDYTRGLEDELDQIAEAKADYQGVISAAWSALDDELGKLDSAGIAAAHP
CPACGKALHRRKGQYGFFWSCTGYPECKTSLPDDKGKPGQRKAPPPSTGFQCPKCGKELARRQGVSKPKKKGMKGRPYDF
YSCTGYPKCDASYQTGPDGKPVFEGAGQQAAE