PAI Gene Information


Name : int
Accession : ACR23128.1
PAI name : HPI
PAI accession : FJ212121
Strain : Escherichia coli 042
Virulence or Resistance: Not determined
Product : P4-like integrase
Function : -
Note : located within a high-pathogenicity-island (HPI) region
Homologs in the searched genomes :   29 hits    ( 25 protein-level,   4 DNA-level )  
Publication :
    -Schubert,S., Darlu,P., Clermont,O., Wieser,A., Magistro,G., Hoffmann,C., Weinert,K., Matic,I. and Denamur,E., "Direct Submission", Submitted (15-SEP-2008) Bacteriology, Max von Pettenkofer-Institut for Hygiene and Microbiology, Marchioninistr. 17, Munich, Bavaria 81377, Germany.

    -Schubert,S., Darlu,P., Clermont,O., Wieser,A., Magistro,G., Hoffmann,C., Weinert,K., Tenaillon,O., Matic,I. and Denamur,E., "Role of intraspecies recombination in the spread of pathogenicity islands within the Escherichia coli species", PLoS Pathog. 5 (1), E1000257 (2009) PUBMED 19132082.


DNA sequence :
CTGGAGGTTGCGTCCCGCACACGGCAGCACCTGAGTAACATAATGCGCCATGCGGTCCATCAGGAGTTAATCGATACGAA
CCCTGCAGCAAACCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCGCTGGAGCGGCTGCCTG
AACTGCTTGAACGTATTGGGGCATATCATCAGGGCCGTGAACTGACCCGGCATGCCGTTCTGCTGATGCTGCATGTGTTC
ATTCGCTCCAGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCCCGACACG
AGAACCCATTATTGGCGTGCGTTATTCCGGCCGCGGGGCAAAAATGCGAATGCCGCATATCGTCCCCCTCTCAGAACAGT
CCATCGCCATTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACCGATCTTCCCCGGCGACCATAACCCGTATAAG
CCAATGTGTGAAAACACGGTCAATAAGGCACTGCGGGTGATGGGTTACGACACGAAAAAGGATATCTGCGGTCACGGCTT
CCGGGCAATGGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGG
AGCGTAATACCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTAGAAGCCCGCAAAGCGATGATGCAGTGGTGGTCG
GATTATCTGGAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Protein sequence :
LEVASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRHAVLLMLHVF
IRSSELRFARWSEIDFTNRVWTIPPTREPIIGVRYSGRGAKMRMPHIVPLSEQSIAILKQIKDITGNNEPIFPGDHNPYK
PMCENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWS
DYLEACRESYAPPYTIGKNKFIP