PAI Gene Information


Name : tcpA
Accession : ACK75641.1
PAI name : VPI
PAI accession : FJ209011
Strain : Vibrio cholerae IEC224
Virulence or Resistance: Virulence
Product : toxin co-regulated pilin
Function : -
Note : -
Homologs in the searched genomes :   8 hits    ( 8 protein-level )  
Publication :
    -Tay,C.Y., Reeves,P.R. and Lan,R., "Importation of the major pilin TcpA gene and frequent recombination drive the divergence of the Vibrio pathogenicity island in Vibrio cholerae", FEMS Microbiol. Lett. 289 (2), 210-218 (2008) PUBMED 19054108.

    -Tay,C.Y., Reeves,P.R. and Lan,R., "Direct Submission", Submitted (13-SEP-2008) School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.


DNA sequence :
ATGCAATTATTAAAACAGCTTTTTAAGAAGAAGTTTGTAAAAGAAGAACACGATAAGAAAACCGGTCAAGAGGGTATGAC
ATTACTCGAAGTAATCATTGTTCTGGGTATTATGGGTGTGGTCTCAGCGGGTGTTGTTACGCTGGCTCAGCGTGCGATTG
ATTCGCAGAATATGACTAAGGCTGCGCAAAATCTAAACAGCGTGCAAATTGCAATGACACAAACTTATCGTAGTCTTGGT
AATTATCCAGCTACCGCAAACGCAAATGCTGCTACACAGCTAGCTAATGGTTTGGTCAGCCTTGGTAAGGTTTCAGCTGA
TGAGGCAAAGAATCCTTTCACTGGTACAGCTATGGGGATTTTCTCATTTCCACGAAACTCTGCAGCGAATAAAGCATTCG
CAATTACAGTCGGTGGCTTGACCCAAGCACAATGTAAGACTTTGGTTACAAGCGTAGGGGATATGTTTCCATTTATCAAC
GTGAAAGAAGGTGCTTTCGCTGCTGTCGCTGATCTTGGTGATTTCGAAACGAGTGTCGCAGATGCTGCTACTGGCGCTGG
CGTAATTAAGTCCATTGCACCAGGAAGTGCCAACTTAAACCTAACTAATATCACGCATGTTGAGAAGCTTTGTACAGGAA
CTGCTCCATTCACAGTAGCTTTTGGTAACAGTTAA

Protein sequence :
MQLLKQLFKKKFVKEEHDKKTGQEGMTLLEVIIVLGIMGVVSAGVVTLAQRAIDSQNMTKAAQNLNSVQIAMTQTYRSLG
NYPATANANAATQLANGLVSLGKVSADEAKNPFTGTAMGIFSFPRNSAANKAFAITVGGLTQAQCKTLVTSVGDMFPFIN
VKEGAFAAVADLGDFETSVADAATGAGVIKSIAPGSANLNLTNITHVEKLCTGTAPFTVAFGNS