PAI Gene Information


Name : topB
Accession : AAW83109.1
PAI name : GGI
PAI accession : AY803022
Strain : Neisseria gonorrhoeae FA 1090
Virulence or Resistance: Not determined
Product : TopB
Function : -
Note : NG5053
Homologs in the searched genomes :   88 hits    ( 88 protein-level )  
Publication :
    -Hamilton,H.L., Dominguez,N.M., Schwartz,K.J., Hackett,K.T. and Dillard,J.P., "Neisseria gonorrhoeae secretes chromosomal DNA via a novel type IV secretion system", Mol. Microbiol. 55 (6), 1704-1721 (2005) PUBMED 15752195.

    -Hamilton,H.L., Dominguez,N.M., Schwartz,K.J., Hackett,K.T. and Dillard,J.P., "Direct Submission", Submitted (29-OCT-2004) Department of Medical Microbiology & Immunology, University of Wisconsin-Madison, 1300 University Ave., 471A MSB, Madison, WI 53706, USA.


DNA sequence :
ATGCGTTTGTTTTTATGTGAAAAACCATCTCAAGCTAAGGACATCGGTAAAGTGCTTGGTGTTCTTGGCGGGAGGCATGA
TGGTTATTTTCAGAATGGAGACACTATTGTTACCTGGGCATTTGGTCATATCCTGACACAGGCCGCGCCAGATGCTTATG
GCGAACAATATGCTGACTTTGGAAATATCTCCGCATTGCCCATTCTCCCTGAAGTTTGGCAGATGCAGGTACCGCCGAAG
GTATCGAAGCAGTTTAAAGTCATTAAAAGCTTGTTGGCCAAAGCAGATGAAGTAGTGATTGCTACTGATGCAGACCGTGA
AGGGGAAGTTATTGCCCGTGAAATATTGGACTACTGTGGCTACCGTAAAAAGATTTCCCGATTTTGGACGAGTGGCCTAG
ATACCCAATCGGTAAAAAAAGCCTTATCTTCAATAATGCCGGGTAAGGATAAAGAAAACCTATATCAGGCCGGTTTGGCG
CGCGGCCGCGCCGACTGGCTGGTAGGTATGAACCTGAGTCGTGCCTACACAGCTGCTTATTCTGCCGGATATGGCCGAGA
ACATATTTTGTCGATCGGACGGATTCAAACACCGACTTTAAAGCTTGTAGTCCAAAGGGATAAAGAGATCGATACTTTCG
TGCCTTACAACTACTACACCCTTTCAGTAGATTTTGAGACAGCAGACAAGTCAGTGTTTACTACACTGTGGCAGGTTCCT
GAAAACTGGCGTAATACTGACGGATACTGTACCAACCTTGAGGCTGTAAAGGCACTTGTCAAACAGCTTGAGAAATCTAC
AGGCAAGGTTATTACCTCAAATAAAGAGCGTAAAAGCACCCCGCCCCCGTTACCGTACAGCCTTTCGGCTTTGCAAAAAG
AAGCCGGTAAAAAACTTGGCCTATCGGCTTCCAAAGTGCTCAAAATTGCACAAACCCTCTACGAAAAATACAAGATCACG
TCATATCCCCGCACCCCTTGCAGATACTTGCCAAAATCGCAGATGAGTGAAGTGAAAGATGTATTTGCCGCGATACAGAC
TATCGATAAATCCATGCTTTCAGTGATTGAAAAAGCTGATCCTGAACGTCAATCAAGGGTATGGAACGATAACCAGGTAA
ACAAACATTCCCATCATGCGATTATTCCGACCAAGGCCAGTAATTTTGATTTGTCAGTCCTGGATAAGAATGAATTAACG
GTGTACCGAATGATACGAGACCGTTATATCGCACAGTTTTATCCAGATTTTGAATATGACTCTACTGTAGTTGAGGTTGA
GGCATGTTCACATTTGTTTAAAGCCTCCAACCAATCACCGGTTATTTCCGGTTGGAAGGTTCTTTTGGGCAAGGACGTGT
TTGAAGGCGATCAAATCGATGAAGGTCCTGCTCTACCACATCTGAAAGTCAACGATGAGGTCGACACGCTTTCCTTCAAT
CCCGAAACTAAAAAGACCACGCCGCCACCGCGCTTTACAGAGGCTTCTCTACTCGATGAGATGCAGACTTTGAAGGACTT
TTTGAAGAATGTAGAAGACGAACAGATCAGAAAAATTCTCAAAAGTACGGAAGGCTTGGGAACGGAAGCCACTCGCGCTA
CCATTATCGATCGTTTGTTTGAAATGGGTTATATGGAAAAGAAACGGAGCAAAATCTATGCGACAGAAAAAGGCCGTAAT
CTGATTGCCCGTATTCCCACTATGATTGCCGATCCGATAACGACAGCCAAATGGGAGCTGGCTTTGGCTGGGATAGAAGC
CGGCAAATTAACTTTAGCTGAATTTATGGCTTATCAGCAGAAAGTGATCACAGAGCTGGTTGGGCAGGCGAAAAAGGATG
CTGTAGGAAAAGCTCGTCCGCCAAAACAGACGGATTCAGCTGGTACAAAAAAACAGGCGGTCGCTCGAAATGAAGACGAT
GTCTGTCCGACCTGTAAGGAAGGCCGTCTGAGACAGAGAGGATTCAAGGAAAACCCTGATAAGCGGTATTGGGGGTGTAG
TAGGTTTCCCGAATGTAAACACTTCGAATGGGTCAAATAA

Protein sequence :
MRLFLCEKPSQAKDIGKVLGVLGGRHDGYFQNGDTIVTWAFGHILTQAAPDAYGEQYADFGNISALPILPEVWQMQVPPK
VSKQFKVIKSLLAKADEVVIATDADREGEVIAREILDYCGYRKKISRFWTSGLDTQSVKKALSSIMPGKDKENLYQAGLA
RGRADWLVGMNLSRAYTAAYSAGYGREHILSIGRIQTPTLKLVVQRDKEIDTFVPYNYYTLSVDFETADKSVFTTLWQVP
ENWRNTDGYCTNLEAVKALVKQLEKSTGKVITSNKERKSTPPPLPYSLSALQKEAGKKLGLSASKVLKIAQTLYEKYKIT
SYPRTPCRYLPKSQMSEVKDVFAAIQTIDKSMLSVIEKADPERQSRVWNDNQVNKHSHHAIIPTKASNFDLSVLDKNELT
VYRMIRDRYIAQFYPDFEYDSTVVEVEACSHLFKASNQSPVISGWKVLLGKDVFEGDQIDEGPALPHLKVNDEVDTLSFN
PETKKTTPPPRFTEASLLDEMQTLKDFLKNVEDEQIRKILKSTEGLGTEATRATIIDRLFEMGYMEKKRSKIYATEKGRN
LIARIPTMIADPITTAKWELALAGIEAGKLTLAEFMAYQQKVITELVGQAKKDAVGKARPPKQTDSAGTKKQAVARNEDD
VCPTCKEGRLRQRGFKENPDKRYWGCSRFPECKHFEWVK