PAI Gene Information


Name : aadA7
Accession : AAT37846.1
PAI name :
PAI accession : AY605684
Strain :
Virulence or Resistance: Not determined
Product : aminoglycoside adenyltransferase
Function : -
Note : confers resistance to streptomycin and spectinomycin
Homologs in the searched genomes :   112 hits    ( 112 protein-level )  
Publication :
    -Srinivasan,V. and Ghosh,A., "Direct Submission", Submitted (04-APR-2004) Molecular Biology, Institute of Microbial Technology, Sector-39 A, Chandigarh, Chandigarh 160036, India.

    -Srinivasan,V.B., Virk,R.K., Kaundal,A., Chakraborty,R., Datta,B., Ramamurthy,T., Mukhopadhyay,A.K. and Ghosh,A., "Mechanism of drug resistance in clonally related clinical isolates of Vibrio fluvialis isolated in Kolkata, India", Antimicrob. Agents Chemother. 50 (7), 2428-2432 (2006) PUBMED 16801422.


DNA sequence :
ATGAGTGAAAAAGTGCCCGCCGAGATTTCGGTGCAACTATCACAAGCACTCAACGTCATCGGGCGCCACTTGGAGTCGAC
GTTGCTGGCCGTGCATTTGTACGGCTCCGCACTGGATGGCGGATTGAAACCGTACAGTGATATTGATTTGCTGGTGACTG
TAGCTGCACCGCTCAATGATGCCGTGCGGCAAGCCCTGCTCGTCGATCTCTTGGAGGTTTCAGCTTCCCCTGGCCAAAAC
AAGGCACTCCGCGCCTTGGAAGTGACCATCGTCGTGCACAGTGACATCGTACCTTGGCGTTATCCGGCCAGGCGGGAACT
GCAGTTCGGAGAGTGGCAGCGCAAAGACATCCTTGCGGGCATCTTCGAGCCCGCCACAACCGATTCTGACTTGGCGATTC
TGCTAACAAAGGCAAAGCAACATAGCGTCGTCTTGGCAGGTTCAGCAGCGAAGGATCTCTTCAGCTCAGTCCCAGAAAGC
GATCTATTCAAGGCACTGGCCGATACTCTGAAGCTATGGAACTCGCCGCCAGATTGGGCGGGCGATGAGCGGAATGTAGT
GCTTACTTTGTCTCGTATCTGGTACACCGCAGCAACCGGCAAGATCGCGCCAAAGGATGTTGCTGCCACTTGGGCAATGG
CACGCTTGCCAGCTCAACATCAGCCCATCCTGTTGAATGCCAAGCGGGCTTATCTTGGGCAAGAAGAAGATTATTTGCCC
GCTCGTGCGGATCAGGTGGCGGCGCTCATTAAATTCGTGAAGTATGAAGCAGTTAAACTGCTTGGTGCCAGCCAATGA

Protein sequence :
MSEKVPAEISVQLSQALNVIGRHLESTLLAVHLYGSALDGGLKPYSDIDLLVTVAAPLNDAVRQALLVDLLEVSASPGQN
KALRALEVTIVVHSDIVPWRYPARRELQFGEWQRKDILAGIFEPATTDSDLAILLTKAKQHSVVLAGSAAKDLFSSVPES
DLFKALADTLKLWNSPPDWAGDERNVVLTLSRIWYTAATGKIAPKDVAATWAMARLPAQHQPILLNAKRAYLGQEEDYLP
ARADQVAALIKFVKYEAVKLLGASQ