PAI Gene Information


Name : cag5 (HP0524)
Accession : AAR03947.1
PAI name : cag PAI
PAI accession : AY330643
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : Cag5
Function : -
Note : cag-beta; jhp0473; orf10; virD4-like protein
Homologs in the searched genomes :   45 hits    ( 43 protein-level,   2 DNA-level )  
Publication :
    -Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates", Gene 328, 85-93 (2004) PUBMED 15019987.

    -Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Direct Submission", Submitted (26-JUN-2003) Biotechnology, Royal Institute of Technology, Alba Nova University Centre, Roslagstullsbacken 21, S-106 91 Stockholm, Sweden.


DNA sequence :
ATGGAAGACTTTTTATATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTTTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAACCAACCTCAAAAGAAAA
AAAACTTTAAAGAAATCATTATAGAGGGGCTGAAAGAAAGAATTAAAACCTTTGGCTTTTGGTTGCAAGCTATACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATCGATTGCCTGA
GAGTGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTGCATACTATTTTAAAGCGCTTTGTTTTA
GTTCACTCAAAATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATCTTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAAACTGAAGAAAAGATGATCAAAGCTAAACTCATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AGGTGATTGTAGGCAGGCGTGGTTTAGGGGATTTTATTGCTTACGCAGGACAGGCGTTCATTGGCTTGATTGCCCCTACT
AGAAGCGGTAAAGGTGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGATCCTAAGGC
TGACACTATGGAAACTTGCGGGAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGGCATGGGATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCAAAGCTCGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAAGCACGAAATCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTTATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCAACGATG
TTTTTCATAGGTTCTATGGCAAGCGGTATCAATTTGATTGATGAAAACACAAACATGGAAAAAGTTGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGACAATCTAAGAGCGCTTAGTCCTACTACTAGAAACATGTGGAATAACT
TCAAGACAATGGGTGGCGCTAAAGAAACTTATAGCTCTGTTCAAGGGGTCTATACTTCAGCGTTTGCGCCTTACAATAAC
GCCATGATCAGGAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGACCGATACTAGAGCTGTTTTTCAATGTGATGATTTATAGCAACCTCATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGCTTAATGCTTATGGATGAATTCACGCTCTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATTATGGCAGAATACAACATGCGTCCCGCTTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTAGGGAAATACACAAGGCAAGATGTGAGCCGAAGC
ATTGATGACAATACCGGTAAGACCAACACTTCTATCAGCAACAAAGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAGAATACGCTCAAACCCATCAAATGCCACAAGGCGCTTTACTATGATGATCCAT
TCTTCACCGATGAACTCATTAAGGTAAGTCCAAGCTTGAGCAAGAAATACAAATTGGGAAAAGTGCCTGATCAAGCAACA
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGTGAATTGAGCTATGACAAGTCTTTAGTGCCTGTGGGTTCAAGTGA
ACTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERIKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNRLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDENTNMEKVVSLMEFFGGEEDKSGDNLRALSPTTRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPDQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL