PAI Gene Information


Name : cag3 (HP0522)
Accession : AAR03914.1
PAI name : cag PAI
PAI accession : AY330640
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : Cag3
Function : -
Note : cag-delta; jhp0471; orf8
Homologs in the searched genomes :   46 hits    ( 46 protein-level )  
Publication :
    -Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates", Gene 328, 85-93 (2004) PUBMED 15019987.

    -Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Direct Submission", Submitted (26-JUN-2003) Biotechnology, Royal Institute of Technology, Alba Nova University Centre, Roslagstullsbacken 21, S-106 91 Stockholm, Sweden.


DNA sequence :
ATGTTTAGAAAACTGGCAACCGCTGTATCGCTCATAGGCTTACTAATCTCTAACACTCTTTATGCTAAAGAAATAAGTGA
AGCCGATAAGGTTATTAAAGCCACTAAAGAAACTAAAGAGACCAAGAAAGAAGCTAAACGACTCAAAAAAGAAGCTAAAC
AGCGCCGACAGATCCCTGATAATAAGAAACCTCAATATGCCTCTGTTGATGACACAAAAACTCAAGCGCTTTTTGATATA
TACGACACCTTGAATGTGAATGACAAAAGCTTTGGGGATTGGTTTGGTAATAGCGCTTTGAAAGACAAAACCTATCTCTA
CGCTATGGATCTATTGGATTATAACAACTACTTATCCATAGAAAATCCCATTATCAAAACAAGAGCAATGGGAACTTATG
CGGATTTGATTATCATCACAGGCTCATTAGAGCAAGTCAATGGGTATTACAACATTCTAAAAGCGCTCAACAAACGCAAC
GCTAAGTTTGTGTTAAAAATCAATGAGAACATGCCTTATGCCCAAGCGACTTTTTTAAGAGTGCCAAAAAGAAGCGATCC
TAATGCCCACACGCTTGATAAGGGAGCGTCAATTGATGAGAATAAGCTTTTTGAACAACAAAAGAAAATGTATTTCAATT
ACGCTAACGATGTGATCTGCAGACCCGATGATGAAGTGTGTTCGCCCCTAAGAGATGAGATGGTAGCTATGCCCACTAGC
GATAGCGTTACTCAAAAACCCAATATCATTGCTCCTTATAGCTTGTATAGACTAAAAGAGACAAATAACGCCAATGAGGC
CCAACCATCACCTTATGCCACTCAAACCGCTCCCGAAAACAGCAAAGAGAAGCTCATAGAAGAGCTAATCGCTAACTCCC
AACTCATAGCCAATGAAGAAGAGAGGGAAAAGAAACTCTTAGCAGAAAAAGAAAAACAAGAGGCTGAATTGGCTAAATAC
AAGCTCAAAGACTTAGAAAATCAAAATAAACTAAAAGCTTTAGAAGCAGAGTTGAAAAAGAAAAACGCTAAGAAACCTAG
AGTAGTGGAAGTGCCTGTTTCTCCTCAAACAAGTAATTCTGATGAAACAATGAGAGTTGTCAAAGAAAAAGAGAACTATA
ATGGGTTATTAGTGGATAAGGAGACCACGATCAAAAGAAGCTATGAGGGGACTTTGATCAGTGAAAATTCTTACAGCAAA
AAAACACCTCTCAACCCTAATGACTTGAGGAGCTTAGAAGAAGAAATTAAGAGCTACTATATCAAGTCTAATGGCTTGTG
TTATACTAATGGCATTAACCTCTATGTAAAAATCAAAAACGACCCCTATAAAGAGGGAATGCTGTGTGGTTATGAGAGTG
TTCAAAATCTGCTCTCACCTCTAAAGGACAAGCTCAAGTATGACAAGCAAAAGTTACAAAAAGCGTTACTGAAAGATTCA
AAATAA

Protein sequence :
MFRKLATAVSLIGLLISNTLYAKEISEADKVIKATKETKETKKEAKRLKKEAKQRRQIPDNKKPQYASVDDTKTQALFDI
YDTLNVNDKSFGDWFGNSALKDKTYLYAMDLLDYNNYLSIENPIIKTRAMGTYADLIIITGSLEQVNGYYNILKALNKRN
AKFVLKINENMPYAQATFLRVPKRSDPNAHTLDKGASIDENKLFEQQKKMYFNYANDVICRPDDEVCSPLRDEMVAMPTS
DSVTQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKEKLIEELIANSQLIANEEEREKKLLAEKEKQEAELAKY
KLKDLENQNKLKALEAELKKKNAKKPRVVEVPVSPQTSNSDETMRVVKEKENYNGLLVDKETTIKRSYEGTLISENSYSK
KTPLNPNDLRSLEEEIKSYYIKSNGLCYTNGINLYVKIKNDPYKEGMLCGYESVQNLLSPLKDKLKYDKQKLQKALLKDS
K