Name : cagA (HP0547)
Accession : AAR03881.1
PAI name : cag PAI
PAI accession : AY330637
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : CagA
Function : -
Note : Cag26; cag26; jhp0495; cytotoxicity associated immunodominant antigen
Homologs in the searched genomes : 48 hits ( 47 protein-level, 1 DNA-level )
Publication :
-Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates", Gene 328, 85-93 (2004) PUBMED 15019987.
-Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Direct Submission", Submitted (26-JUN-2003) Biotechnology, Royal Institute of Technology, Alba Nova University Centre, Roslagstullsbacken 21, S-106 91 Stockholm, Sweden.
| DNA sequence : | |
ATGATACCAAATTTAATGATACCAAATTTAGGTATAGAAGGAGAAACAATGACTAACGAAACCATTAACCAACAACCACA
AACCGAAGCGGCTTTTAACCCGCAGCAATTTATCAATAATCTTCAAGTGGCTTTTCTTAAAGTTGATAACGCTGTCGCTT
CATACGATCCTGATCAAAAACCAATCGTTGATAAGAACGATAGGGATAACAGGCAAGCTTTTGAGGGAATCTCGCAATTA
AGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAATCAGTATTTTTCAGACTTTATCGATAAGAGCAA
TGATTTAATCAACAAAGACAATCTCGTTGATGTGGAATCTTCCACAAAGAGCTTTCAGAAATTTGGGGATCAGCGTTACC
AAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCAACACCCGATCGATCCGAAATTTTATGGAAAAT
ATCATACAACCCCCTATCCCTGATGACAAAGAAAAAGCAGAGTTTTTGAAATCTGCCAAACAAGCTTTTGCAGGAATCAT
TATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGGCGTATTTGATGAATCTTTGAAAGAAAGGCAAGAAGCAGAAA
AAAATGGAGGGCCTACTGGTGGGGATTGGTTGGATATTTTTTTATCATTTGTGTTCAACAAAAAACAATCTTCCGATCTC
AAAGAAACGCTCGATCAAGAACCAGTTCCTCATGTCCAACCAGATATAGCCACTACCACCACCGACATACAAGGCTTACC
GCCTGAAGCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATTCACTCTTGGCGATATGGAAATGTTAGATGTTG
AGGGAGTCGCTGACATTGATCCCAATTACAAGTTCAACCAATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATG
GGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGGGGGCAATGGTGGTTTTGGAGCCAAGCACGATTG
GAACGCCACCGTTGGTTATAAAGACCAACAAGGTAACAATGTGGCTACAATAATTAATGTGCATATGAAAAACGGCAGTG
GCTTGGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTTATCTCTACAAAGAAGACCAACTCACAGGCTCA
CAGCGAGCATTGAGTCAAGAAGAGATCCAAAACAAAATAAATTTCATGGAATTTCTTGCACAAAATAATGCTAAATTAGA
CAACTTGAGCGAGAAAGAGAAGGAAAAATTCCGAACTGAGATTGAAGATTTTCAGAAAGACTCTAAGGCTTATTTAGATG
CCCTAGGGAATGATCGTATTGCTTTTGTTTCTAAAAAAGACACAAAACATTCAGCTTTAATTACTGAGTTTGGTAATGGG
GATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAAAGCTTTAGATAGGGAGAAAAATGTTACTCTTCAAGG
TAGCCTAAAACATGATGGCGTGATGTTTGTTGATTATTCTAATTTCAAATACACCAACGCCTCCAAGAATCCCAATAAGG
GTGTAGGCGTTACGAATGGCGTTTCCCATTTAGAAGCAGGCTTTGACAAGGTAGCTGTCTTTAATTTGCCTGATTTAAAT
AATCTCGCTATCACTAGTTTCGTAAGGCGGAATTTAGAGGATAAACTAGCCACTAAAGGATTGTCCCTACAAGAAGCTAA
TAAGCTTATCAAAGACTTTTTGAACAGCAACAAAGAATTGGTTGGAAAAGCTTTAAACTTCAATAAAGCTGTAGCTGAAG
CTAAAAACACAGGCAACTATGATGAAGTGAAAAAAGCTCAGAAAGATCTTGAAAAATCTCTAAAGAAACGAGAGCATTTA
GAGAAAGAAGTAGCGAAAAAATTGGAGAGTAAAAGCGGCAACAAAAATAAAATGGAAGCGAAATCTCAAGCTAACAGCCA
AAAAGATGAGATTTTTGCGTTGATCAATAAAGAGGCTAATAGAGACGCAAGAGCAATCGCTTACGCTCAAAATCTTAAAG
GCATCAAAAGGGAATTGTCTGATAAACTTGAAAATATCAACAAGGATTTGAAAGACTTTAGTAAATCTTTTGATGAATTC
AAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAAACGCTAAAAGCCCTTAAAGGCTCGGTGAAAGATTTAGGTAT
CAATCCAGAATGGATTTCAAAAGTTGAAAACCTTAATACAGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATTTCA
GCAAGGTAACGCAAGCAAAAAGCGACCTTGAAAATTCCATTAAAGATGTGATCATCAATCAAAAGATAACGGATAAAGTT
GACAATCTCAATCAAGCTGTATCAATAGCTAAGGCAACAGGCGATTTCAGTGGGGTAGAGCAAGCGCTAGCCGATCTCAA
GAATTTCTCAAAAGGACAATTGGCTCAACAAGCTCAAAAAAATGAAGATTTCAATACTGGAAAAAATTCTGAAATATACC
AATCCGTTAAGAATGGTGTGAATGGAACCCTAGTCGGTAATGGGTTATCTAAAGCAGAAGCCACAACTCTTTCTAAAAAC
TTTTCGGACATCAAGAAAGAGTTGGAAGCAAAATTGGGAAATTTCAATAACAATAACAATAATGGACTCAAAAACGAACC
CATTTATGCTAAAGTTAATAAAAAGAAAGCAGGACAAGCAGCTAGCCCTGAAGAACCCATTTACGCTCAAGTTGCTAAAA
AGGTAAATGCAAAAATTGACCGACTCAATCAAATAGCAAGTGGTTTGGGTGGTGTAGGGCAAGCAGCGGGCTTCCCTTTG
AAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAGCTAACCATGAACCCATTTACGCTACGATTGATGA
TCTCGGCGGATCTTTCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAAGGAATCAAGAAT
TGGCTCAGAAAATTGACAATCTCAATCAGGCGGTATCAGAAGCTAAAGCAGGTTTTTTTGGCAATCTAGAGCAAACGATA
GACAATCTCAAAGATTCTACAAAATACAATTCCGTGAATCTATGGGCTGAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTC
AGCGAAATTGGACAATTACGCTATTAACAGCCACACACGCATTAATAGCAATGTCAAAAATGGAGCAATCAATGAAAAAG
CGACCGGCATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAAGC
GTTCCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCAC
CAAGTTGAACAATGCTGTAAAAGACACTAAGTCTGGCTTTACGCGATTTTTAGCCAATGCATTTTCTACAGCATCTTATT
ACTACTTCTTGGCGGGGGAAAATGCGGAGCATGGAATCAAAAATGTTAATACAAAAGGTGGTTTCCAAAAATCTTAA
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| Protein sequence : | |
MIPNLMIPNLGIEGETMTNETINQQPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNRQAFEGISQL
REEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLVDVESSTKSFQKFGDQRYQIFTSWVSHQNDPSKINTRSIRNFMEN
IIQPPIPDDKEKAEFLKSAKQAFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFVFNKKQSSDL
KETLDQEPVPHVQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLM
GSHNGIEPEKVSLLYGGNGGFGAKHDWNATVGYKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGS
QRALSQEEIQNKINFMEFLAQNNAKLDNLSEKEKEKFRTEIEDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGNG
DLSYTLKDYGKKADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGVTNGVSHLEAGFDKVAVFNLPDLN
NLAITSFVRRNLEDKLATKGLSLQEANKLIKDFLNSNKELVGKALNFNKAVAEAKNTGNYDEVKKAQKDLEKSLKKREHL
EKEVAKKLESKSGNKNKMEAKSQANSQKDEIFALINKEANRDARAIAYAQNLKGIKRELSDKLENINKDLKDFSKSFDEF
KNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNTALNEFKNGKNKDFSKVTQAKSDLENSIKDVIINQKITDKV
DNLNQAVSIAKATGDFSGVEQALADLKNFSKGQLAQQAQKNEDFNTGKNSEIYQSVKNGVNGTLVGNGLSKAEATTLSKN
FSDIKKELEAKLGNFNNNNNNGLKNEPIYAKVNKKKAGQAASPEEPIYAQVAKKVNAKIDRLNQIASGLGGVGQAAGFPL
KRHDKVDDLSKVGLSANHEPIYATIDDLGGSFPLKRHDKVDDLSKVGLSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTI
DNLKDSTKYNSVNLWAESAKKVPASLSAKLDNYAINSHTRINSNVKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGS
VPLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDTKSGFTRFLANAFSTASYYYFLAGENAEHGIKNVNTKGGFQKS
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