PAI Gene Information


Name : esp
Accession : AAQ84025.1
PAI name : Not named
PAI accession : AY322150
Strain : Enterococcus faecium Aus0004
Virulence or Resistance: Virulence
Product : Esp
Function : -
Note : enterococcal surface protein; ORF3
Homologs in the searched genomes :   No hits  
Publication :
    -Leavis,H., Top,J., Shankar,N., Borgen,K., Bonten,M., van Embden,J. and Willems,R.J., "A novel putative enterococcal pathogenicity island linked to the esp virulence gene of Enterococcus faecium and associated with epidemicity", J. Bacteriol. 186 (3), 672-682 (2004) PUBMED 14729692.

    -Willems,R.J.L., Top,J., Borgen,K., Bonten,M.J.M. and van Embden,J.D.A., "Direct Submission", Submitted (12-JUN-2003) Diagnostic Laboratory for Infectious Diseases and Perinatal Screening, National Institute for Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, Bilthoven 3720 MA, Netherlands.


DNA sequence :
ATGGTTAGCAAGAATAATAAGAGAGTATTTCTAGAAAAAACAAAGAAACGAGTATTGAAGTACAGTATCAAAAAATTAAG
TGTTGGGGTTGCATCTGTTTTGGTTGGTGTTGGTCTTGTCTTGGGAACAACTGAACTAGTTCAAGCACAAGATGAAATTT
CTCCAAGCACCCCACTTGAAACAGCGATAAGCTCCGTACAAGTAGGTGACAAAGTAGCTTCGGGGAATACTTTTCAGGAG
AATCCTGGTTATACGAAAAATTATAACTTTTCGGATTTACAATTTAGTCCTCAAGAACTAACTGGAGACACACTAAAAGG
CAATACAATTGGATTTGAAGTTTACGGAAAACATAATATTGCAGCATCAACTAAAAACTGGGAAATCCGTCTTCAATTAG
ATGAACGATTAGCTAAATATGTAGAAAAAATTCAGGTCGATCCAAAGAAAGGAATTGGATCTTCTAGACGGACCTTTGTA
AGAATTAATGATTCGCTGGGTAGACCTACAAATATTTGGAAGGTCAATTATATTCGTGCAAGTGATGGATTATTTGCTGG
GGCTGAAACAACTGATACACAAACTGCTCCTAATGGGGTAATTACGTTTGAAAAGAGCTTAGATGAAATTTTTAAAGAGA
TAGGCATAGACAATCTCAAGACCGATCGTTTAATGTATCGAATCTACTTGGTAAGTCATCAAGACGATGATAAAATTGTA
CCAGGTATTGATAGTACGGGCTACTTTTTAACAGATTCAGATGATTTCTATAATAGCTTAGATGTATCTGAAAATAATCC
TGACCAGTTTAAACATGGATCAGTAAGTGCAAAATATGAGGAACCTAATACTCAAACAAAAGATGGTTCAGGATCCACAG
GTGCTAATGGAGCTATAATCTTAGATCATAAGTTAACGAAAAATTATAATTTCTCATATTCAGCTTCCGCAAAGGGCACG
CCTTGGTATGCTAATTACAAAATTGATGAACGATTAGTTCCATATGTAGCGGGTATACAGATGCACATGGTTCAGGCTGA
CAAAGTAACATATGATGTTTCTTTTGAATCAGGGAAAAAAGTGGCTGATTTAGCAATTGAACGGCGCAAAGATCATGAAA
ATTATGGTGTAGGTTCAATTACTGATAATGATCTTACCAAACTTATTGATTTTGCTAATGCAAGTCCACGTCCAGTCGTT
ATTCGATATGTTTTACAATTGACTAAGCCATTAGATGAAATCTTAGAAGATATGAAAGCAACAGCACAAGTTGAAGAAAA
TAAACCATTTGGTGAAGATTTCATCTTTGATTCTTGGTTGTCGGATACGAATAAAAAATTAATCCAGAACACTTATGGAA
CAGGTTATTATTATTTGCAAGATATTGATGGTGATGGAAACCCTGACGATAAAGAAGAGAGCGGAGACACGAATCCATAT
ATCGGGAAACCTGAATTAGAAGAAGTATATGATGTTGACACAACAGTTAAGGGGAAAGTATTCATCCACGAGTTAGCGGG
AACAGGTCACAAAGCCCAACTTGTTGATAAAGAAGGTACTGTATTAGCAGAAAAAACTATCGCTCCAAATGAAAAAGATG
GGGCTCCAATTTCAGATACTGTAGAATTTGAATTTACGGGTGTAGATTCAAGTAAATTAATCGCGAAAGATGAATTAAAA
ATCCAAATCGTTTCTCCAGGTTTTGATAAACCAGAAGAAGGTTCAACCGTTATTAAGGAATCACCAAAAGCGGTTGATAA
ACAAACCGTGGTAGTTGGATTTAAACCAGATGCTAAAGAATCAATTCGGAATAATAAAAACTTACCTGAAGATGCAGAGT
ATTCATGGAAAACAGAGCCTGATACTTCTAACGTTACTGATAGTACGAAAGGTATTGTAACTGTTAAGATCGGAAATCGA
ACTTTCGACGTGGATGTAGAGTTTGCTGTAAAAGCTTCTCAAGCTATGGAAAATGATGCAACATACGTACCTATAACAAC
AACTCCAGAAACGACAGTTCAAAGTGGAAAACCTACATTTGATAAACCAGATGTTCCTTTAGCTAAAGATGCCTTTTCAA
TTTTAGATGTCTATAATAAGGACTTCGGTAATGCAAGTGTTGATGCAAATACTGGTATTGTTACATTCACTCCAGCTAAA
GGTGTAGGAGAATCGGAGCCGATTACTGGAACAATTCCTATTAAAATTGTTTACCAAGATGGTTCTGTAGGCACGACCGA
TTTAGCAGTAACTGTAAGTAAAGATATTTATGAAAATCCAGGAGAAAACATTCCTGCAGGCTACCACAAAGTGACCTTCA
CCGCAGGGGAAGGAACAAGTATTGAAAGTGGAACAACGGTCTTTGCAGTGAAAGATGGCGTAAGCTTACCAGAAGATAAA
CTTCCAGTGTTGAAAGCAAAAGATGGTTATACAGATGCGAAATGGCCAGAAGAAGCAACTCAACCAATTACAGCAGATGA
TACAGAATTTGTATCAAGTGCAACAAAACTGGATGATATCATTGAAAATCCAGGAGAAAACATTCCTGCAGGCTACCACA
AAGTGACCTTCACCGCAGGGGAAGGAACAAGTATTGAAAGTGGAACAACGGTCTTTGCAGTGAAAGATGGCGTAAGCTTA
CCAGAAGATAAACTTCCAGTGTTGAAAGCAAAAGATGGTTATACAGATGCGAAATGGCCAGAAGAAGCAACTCAACCAAT
TACAGCAGATGATACAGAATTTGTATCAAGTGCAACAAAACTGGATGATATCATTGAAAATCCAGGAGAAAACATTCCTG
CAGGCTACCACAAAGTGACCTTCACCGCAGGGGAAGGAACAAGTATTGAAAGTGGAACAACGGTCTTTGCAGTGAAAGAT
GGCGTAAGCTTACCAGAAGATAAACTTCCAGTGTTGAAAGCAAAAGATGGTTATACAGATGCGAAATGGCCAGAAGAAGC
AACTCAACCAATTACAGCAGATGATACAGAATTTGTATCAAGTGCAACAAAACTGGATGATATCATTGAAAATCCAGGAG
AAAACATTCCTGCAGGCTACCACAAAGTAATCTTCACCGCAGGGGAAGGAACAAGTATTGAAAGTGGAACAACGGTCTTT
GCAGTGAAAGATGGCGTAAGCTTACCAGAAGATAAACTTCCAGTGTTGAAAGCAAAAGATGGTTATACAGATGCGAAATG
GCCAGAAGAAGCAACTCAACCAATTACAGCAGATGATACAGAATTTGTATCAAGTGCAACAAAACTGGATGATATCATTG
AAAATCCAGGAGAAAACATTCCTGCAGGCTACCACAAAGTAATCTTCACCGCAGGGGAAGGAACAAGTATTGAAAGTGGA
ACAACGGTCTTTGCAGTGAAAGACGGCGTAAGCTTACCAGAAGATAAACTTCCAGTGTTGAAAGCAAAAGATGGTTATAC
AGATGCGAAATGGCCAGAAGAAGCAACTCAACCAATTACAGCAGATGATACAGAATTTGTATCAAGTGCAACAAAACTGG
ATGATAAATCTGACGCTGACAAATATAATCCTGAAGGTCAAAAAGTGACTACAGAATTGAATAAGGAACCAGACGCATCT
GAGGGAATTAAGAACAAAGAAGATTTACCAAAAGATACTAAGTATACTTGGAAAGAAAAAGTAGATGTTAGCGCAGCTGG
AAATAAAAAAGGTACGGTTGTAGTGACATATTCAGATGGATCATCTGATGAAGTTGAAGTAGATGTTACAGTGACAGACA
ATCGTTCTGACGCCGATAAATATGAGCCAACAGTAGAAGGCGAAAAAGTAGAAGTTGGAGGCACAGTAGATCTAACAGAT
AATGTTACTAACTTGCCAACATTACCAGAAGGAACAACAGTAACAGATGTCACTCCTGATGGTACGATTGATACCAACAC
ACCAGGTAATTACGAAGGGGTTATCGAAGTAACGTATCCAGATGGTACGAAAGATACAGTGAAAGTTCCAGTAGAAGTGA
CAGACAATCGTTCTGATGCCGATAAATATACACCAATGGTAGAAGGTGAAAAAGTAGAAGTTGGAGGCACAGTAGATCTA
ACAGATAATGTTACTAACTTGCCAACATTACCAGAAGGAACAACAGTAACAGATGTCACTCCTGATGGTACGATTGATAC
CAACACACCAGGTAATTACGAAGGGGTTATCGAAGTAACGTATCCAGATGGTACGAAAGATACAGTGAAAGTTCCAGTAG
AAGTGACAGACAATCGTTCTGATGCCGATAAATATACACCAATGGTAGAAGGTGAAAAAGTAGAAGTTGGAGGCACAGTA
GATCTAACAGATAATGTTACTAACTTGCCAACATTACCAGAAGGAACAACAGTAACAGATGTCACTCCTGGTGGTACGAT
TGATACCAACACACCAGGTAATTACGAAGGGGTTATCGAAGTAACGTATCCAGATGGTACGAAAGATACAGTGAAAGTTC
CAGTAGAAGTGACAGACAATCGTTCCGATGCCGATAAATATGAACCAACAGTAGAAGGCGAAAAAGTAGAAGTTGGAGGC
ACAGTAGATCTAACAGATAATGTTACTAACTTGCCAACATTACCAGAAGGAACAACAGTAACAGATGTCACTCCTGGTGG
TACGATTGATACCAACACACCAGGTAATTACGAAGGGGTTATCGAAGTAACGTATCCAGATGGTACGAAAGATACAGTGA
AAGTTCCAGTAGAAGTGACAGACAATCGTTCTGATGCCGATAAATATACACCAATGGTAGAAGGTGAAAAAGTAGAAGTT
GGAGGCACAGTAGATCTAACAGATAATGTTACTAACTTGCCAACATTACCAGAAGGAACAACAGTAACAGATGTCACTCC
TGATGGTACGATTGATACCAACACACCAGGTAATTACGAAGGGGTTATCGAAGTAACGTATCCAGATGGTACGAAAGATA
CAGTGAAAGTTCCAGTAGAAGTGACAGACAATCGTTCCGATGCCGATAAATACAATCCTGAAGGACAAAAAGTGACTACA
GACTTAAATAAAGAGCCAGACGCATCTGAGGGAATTAAGAACAAAGAAGATCTACCAAAAGGAACTACTTATACTTGGAA
AGAGAAAGTAGATGTTAGTACAGCTGGAAACAAAAAAGGGATTGTAGTAGTAACATATCCAGATGGATCTAAAGAAGAAG
TAGAGGTTACTATTTCTGTAGAAGATAAAAAAGCACCGAATAAACCTCAAGTTGATCCTATTACAGAGGGTGACCAAATT
GTTACTGGTAAAACTGAACCAAATGCAGAGGTGACAGTTACATTACCAAACGGGAGTCAATACCATGGGACAGCTGATAA
AAATGGTAATTTTACAGTTAAAGTTCCTAAATTAGAGGCAGGAACAAAAGTGATAGTAACTGCAACTGATGAATCTGGTA
ATACTAGTGAACCTACTAATGTAGTTGTTTCTTCAAACGAAAAAGACAGTGAAAAAGCCGTTAGTAAAGATAATAAGACT
GACAATCAAGGTAGCAAGCAAAACACAAATAGAGGCAAAAGCAGTCCTCAAAAGCAGTCCTCAAAAGCTTATCCTAAGAC
GGGAGAGATTGATAGTAATATCTTTACTATTAGTGGTGGTTTAATCCTGTTAGGAACTTTAGGGTTATTAGGGTATAAAA
ATCGAAAAAAAGAGAATGAATAG

Protein sequence :
MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTTELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQE
NPGYTKNYNFSDLQFSPQELTGDTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDNLKTDRLMYRIYLVSHQDDDKIV
PGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVSAKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGT
PWYANYKIDERLVPYVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFANASPRPVV
IRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQNTYGTGYYYLQDIDGDGNPDDKEESGDTNPY
IGKPELEEVYDVDTTVKGKVFIHELAGTGHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELK
IQIVSPGFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSNVTDSTKGIVTVKIGNR
TFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDKPDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAK
GVGESEPITGTIPIKIVYQDGSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDK
LPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSL
PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKD
GVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVIFTAGEGTSIESGTTVF
AVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVIFTAGEGTSIESG
TTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAS
EGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYSDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDLTD
NVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYTPMVEGEKVEVGGTVDL
TDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYTPMVEGEKVEVGGTV
DLTDNVTNLPTLPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEVGG
TVDLTDNVTNLPTLPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYTPMVEGEKVEV
GGTVDLTDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYNPEGQKVTT
DLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQI
VTGKTEPNAEVTVTLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSEKAVSKDNKT
DNQGSKQNTNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGLLGYKNRKKENE