PAI Gene Information


Name : S1
Accession : AAQ19124.1
PAI name : PAI I CL3
PAI accession : AY275838
Strain : Escherichia coli 042
Virulence or Resistance: Not determined
Product : putative hemolysin activator HlyB
Function : -
Note : similar to Escherichia coli O157:H7 EDL933 Z1640 gene encoded by GenBank Accession Number AE005312 and to Yersinia pestis CO92 putative hemolysin activator protein encoded by GenBank Accession Number CAC91296
Homologs in the searched genomes :   138 hits    ( 138 protein-level )  
Publication :
    -Shen,S., Mascarenhas,M., Rahn,K., Kaper,J. and Karmali,M.A., "Direct Submission", Submitted (14-APR-2003) Laboratory for Foodborne Zoonoses, Health Canada, 110 Stone Road West, Guelph, Ontario N1G 3W4, Canada.

    -Shen,S., Mascarenhas,M., Rahn,K., Kaper,J.B. and Karmali,M.A., "Evidence for a hybrid genomic island in verocytotoxin-producing Escherichia coli CL3 (serotype O113:H21) containing segments of EDL933 (serotype O157:H7) O islands 122 and 48", Infect. Immun. 72 (3), 1496-1503 (2004) PUBMED 14977955 REMARK Erratum:[Infect Immun. 2004 Jul;72(7):4330. Karmal MA [corrected to Karmali MA]].


DNA sequence :
ATGTCTGTTTTACTATCGCCTTTATCTCTTCAGGCAGCGGATATCCGGCGTAGTGGAGAGGATACATTTATCATTCAGCA
GCAGCGTCAGGAAGCCCTTGAGCAACAACTGACGCCTTCAGCCCCTGATGTTCGCCTTTCTGCACCTGGCTCTTTTGCCC
ATAAGATTAATTTTCCTGTTGAAACGCCCTGTTTTCAGATTAAACAGACGGAACTGAAGGGGGCTGATGCGTTACCACAC
TGGCTGCCTTTACAAAAAATCGCCAACGGGGCGGTCGGGCATTGCCTGGGGGCGAAAGGAATTAATCTGCTGATGAGTAC
ATTGCAGAACCGTCTGGTCGATCATGGTTATGTCACCACCCGTGTTCTGGCACCTTCGCAGGATTTAAAAAGCGGTATCC
TCCGGCTGGTTATTATTCCCGGTGTTGTGCGACATGTGCGTCTGACACCGGACAGTGATGACTATATTCAGTTGTATTCC
TCATTCCCGGCACACGAAGGTTCTCTGCTGGATTTACGGGACATTGAGCAGGGGCTGGAGAATATGCAACGACTGCCGGG
TGTGCAGGCTGATATGGAAATTATGCCCGGTGAGCAGCCAGGGGAAAGTGATATTCTTATTACCCGTAAACAGGATAAAT
ACTGGCGACTGGGGTTTTCGCTTGATGATTCAGGTACCCGCAGCACAGGGCGTTATCTCGGTGGTATAACATTTTCTCTG
GATAATCCTTTTTCCCTGAGTGACCTGCTGTATGTTTCTGCCACCCATAATTTTCCACATTACGGGGGTAAGGGCAGTAA
AAACTACACGGCCCATTACTCTGTGCCTTTCGGTTACTGGCAGTTTTCCGTCACCGCCAGTGATTACGATTACCATCAGA
CGGTAGCTGGTGCGGTTGAGGATTACCAGTACAGTGGCGAGAGTCAGAATCTGGGCATGCAGCTGAGCCGGGTACTGCAC
CGTAACGGGACGCAGAAAACGGTGCTGACTTACGATGTTCAGGCCCGCAGGTCGCGTAACTACATTAATGATAGGGAAAT
CCAGGTGCAGCGCCGGCAGACAGCGGCCTGGCGACTTGGGCTGCAGCACCGTCATTATATTTCTCAGGCCACACTGGATG
CTGGTGTCAGCTGGCAACGGGGAACCCGCTGGTTTGGTGCTCAGCCGGCACCGGAGGAAATCTTCGGTGAGGCAACGGCG
CTCAGTAAGATCCTGCAGATGAATGCATCCTTTAATCTGCCCTTTACACTGGCAGAGCAGCCCTTCAGTTATTCCTTCCG
GTATCAGCGCCAGCTGAGCAATACCCCGCTGACCCCACAGGAACAGTTTGCCATCGGTAACCGCTGGACGGTTCGTGGTT
TTGACGGGGAGCGAACGCTGAATGCCAGTAACGGCTGGTATATCCGCAACGACCTGGCCTGGCGTACGCCACTGCCGGAG
CAGGAGTTATATCTGGGAATGGATTACGGCGAGGTGGGGGGAGCCGGCAGTGAATATCTGGTGGGACGTCATCTGGCCGG
TGGTGTTGTGGGGCTGAGGGGGCAACTGTTCAGTACGGATTATGACGTTTTCATCGGTCGTCCGTTTTCAAAGCCGGCGG
GTTTTATGACGAGTGATGTGACAGCCGGTTTTAATCTGTTCCGGGATTTCTGA

Protein sequence :
MSVLLSPLSLQAADIRRSGEDTFIIQQQRQEALEQQLTPSAPDVRLSAPGSFAHKINFPVETPCFQIKQTELKGADALPH
WLPLQKIANGAVGHCLGAKGINLLMSTLQNRLVDHGYVTTRVLAPSQDLKSGILRLVIIPGVVRHVRLTPDSDDYIQLYS
SFPAHEGSLLDLRDIEQGLENMQRLPGVQADMEIMPGEQPGESDILITRKQDKYWRLGFSLDDSGTRSTGRYLGGITFSL
DNPFSLSDLLYVSATHNFPHYGGKGSKNYTAHYSVPFGYWQFSVTASDYDYHQTVAGAVEDYQYSGESQNLGMQLSRVLH
RNGTQKTVLTYDVQARRSRNYINDREIQVQRRQTAAWRLGLQHRHYISQATLDAGVSWQRGTRWFGAQPAPEEIFGEATA
LSKILQMNASFNLPFTLAEQPFSYSFRYQRQLSNTPLTPQEQFAIGNRWTVRGFDGERTLNASNGWYIRNDLAWRTPLPE
QELYLGMDYGEVGGAGSEYLVGRHLAGGVVGLRGQLFSTDYDVFIGRPFSKPAGFMTSDVTAGFNLFRDF