Name : topA (RL092)
Accession : AAP84217.1
PAI name : PAPI-1
PAI accession : AY273869
Strain : Pseudomonas aeruginosa B136-33
Virulence or Resistance: Not determined
Product : topoisomerase I
Function : -
Note : similar to XFa0003 in Xylella fastidiosa 9a5c
Homologs in the searched genomes : 9 hits ( 9 protein-level )
Publication :
-He,J. and Rahme,L.G., "Direct Submission", Submitted (09-APR-2003) Department of Surgery and Department of Molecular Biology, Massachusetts General Hospital and Boston Shriners Institute, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
-He,J., Baldini,R.L., Deziel,E., Saucier,M., Zhang,Q., Liberati,N.T., Lee,D., Urbach,J., Goodman,H.M. and Rahme,L.G., "The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes", Proc. Natl. Acad. Sci. U.S.A. 101 (8), 2530-2535 (2004) PUBMED 14983043.
| DNA sequence : | |
ATGCACATCGTAATCATTGAAGCCCCGGGCAAGCTGAAAAAGCTGAGGTCCCTTCTCCCCTCGATTCGTCCCGACGTGAC
CTGGCAGGTCGAGGCGACAGCCGGCCACATCAGAGACCTACCCGTTCACGGGCAGGATCCGCAGATGCTCACCGTCGGCG
TGGGCCAGGATTTCAAACCGCACTACCAGATCCTCTCGGGCAAGGAAAAAACCGTCGCACGGCTGAAGGAGCTGCGGCAG
AAAGCCGTGGAAATCTACGTCGCATCGGACCCGGATCGCGAAGGCGAAAGCATTGGCTGGCACATCCTCCAAGCTGCCGG
GATCAAGAACTACAAGCGCGTTGCCTTCAAAGAAATCACAAAGTCATGCATCACCGCCGAACTCAGCTCGCCGCGTCGCC
TGGACCTCCCGAAGGTCGCCTCGCAGGAATGCCGTCGCGTCATCGATCGCCTGGTGGGGTATCTGGTCACGCCAGAGTTG
CGGCGCGTGATGGGTAGGCCGACCACCGCCGGGCGCGTGCAGTCCGTCGCGGTGTACCTGGTGGTCCTGCGAGAGCGGGA
GATCCGCGCCTTCACAGCAATCAAGCACTTCGGGGTGGAACTGACCTTCGTTTCGCCCAGCGACGGCCGTACCTGGACGG
CGGAATGGGATCCAGTGCCCGTGTTTGCCAGCGAGGAGTTCCCGTATGTCCAGGATCGTCAACTCGCAGAACTGGTGGGG
GCTATACGTAATGTCATCGTCGAGACCTGCATTGATAGCGAAGAAACCGATGCGCCTCCGGCACCGTTCATCTCCTCCTC
GCTCCAGATGGCCGCCGGGAATGCGCTGAAGTGGTCACCCGACAAGACGATGAAGGTCGCCCAGCGGCTGTATGAACAGG
GGCTCATCACCTACCACCGGACGGACAACCCCAATATCTCGAAGGACTCGATGCCGGATATCCGTGCTGTCGCCAAAGCC
TTGGGGCTGAAGTGTGTTGAGCAACAGCGGATGTTCAAAGCGGACCAAGACGCCCAGGAAGGCCACCCCGCCATCACCCC
TACCGACTGGATGGCCGCTGCCGCCGGTGAAACTGCTGATGAGCAGGCGCTGTACCAGCTCATTCGAGTCCGCGCGCTTG
CCAGTCAGATCGAAGCTGCCGTGTACGCAGTGAGAACCATCACCCTCCTGGGCGTCGGCCCCGACAAAAAGCCGCTGCGC
TTCGGCGCCAAAGGGAAGCTGTTGAACGTGCCTGGCTGGAGAAAACTGCTGCAGGGTGATGACGCCGAGGAGCAGAAGAA
CGAAACGCCTTCAAACCCCATCCCGATCCCGGCGCTGGAGCCACGCCAGATACTCAAGGTCTACAGCGGCGAGGTCCTGG
AGAAGAAAACCACCCCTCCCAAGCGATTCACCGACGCCAGCCTGGTGGGCGAGATGAAGCGCCGCGGGATTGGTCGGCCA
TCCTCCTACGCCTCGATCGTGAAGAACATCATCGACAAGGGCCAGGTGCAGATGAAGGGGCGAAGCCTGATCCCCGGCGA
GCTGGGAGAGGCCACCATCGCGCTCCTGGAGCACAACTTCAGCTTCCTCAGCCTCGACTTCACCCGCAACCTCGAGGTCG
CCTTGGACCGGATCGCCAACAGCGAGGACACCTACATGAACGTGGTCCAGCAGTTCTACCAGCTACTACAGACAGAGCTG
CAGACACTCCGCGCGCTCCCCAGCGCACAGGACGAACCACGCGCAAGCTCCACCGCCAGTATCTCCTCGGCGCCGACCAG
CGACTTCCTTTGCGGCAAGTGCGGTCTGCCCCTGGTTCACCGCAAGAAAGCCGGCAAAGGCGGCTTCGACTTCTGGGGTT
GCAGCGGCTATCGAACAACAGGGTGCAAGGTTAGCTACCCCACCAAGAGCGGCCGGCCTGACTTCGACAACCCGCGCGGG
CTATAG
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| Protein sequence : | |
MHIVIIEAPGKLKKLRSLLPSIRPDVTWQVEATAGHIRDLPVHGQDPQMLTVGVGQDFKPHYQILSGKEKTVARLKELRQ
KAVEIYVASDPDREGESIGWHILQAAGIKNYKRVAFKEITKSCITAELSSPRRLDLPKVASQECRRVIDRLVGYLVTPEL
RRVMGRPTTAGRVQSVAVYLVVLREREIRAFTAIKHFGVELTFVSPSDGRTWTAEWDPVPVFASEEFPYVQDRQLAELVG
AIRNVIVETCIDSEETDAPPAPFISSSLQMAAGNALKWSPDKTMKVAQRLYEQGLITYHRTDNPNISKDSMPDIRAVAKA
LGLKCVEQQRMFKADQDAQEGHPAITPTDWMAAAAGETADEQALYQLIRVRALASQIEAAVYAVRTITLLGVGPDKKPLR
FGAKGKLLNVPGWRKLLQGDDAEEQKNETPSNPIPIPALEPRQILKVYSGEVLEKKTTPPKRFTDASLVGEMKRRGIGRP
SSYASIVKNIIDKGQVQMKGRSLIPGELGEATIALLEHNFSFLSLDFTRNLEVALDRIANSEDTYMNVVQQFYQLLQTEL
QTLRALPSAQDEPRASSTASISSAPTSDFLCGKCGLPLVHRKKAGKGGFDFWGCSGYRTTGCKVSYPTKSGRPDFDNPRG
L
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