PAI Gene Information


Name : ef0090
Accession : AAM75293.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : EF0090
Function : -
Note : osmosensitive K+ sensor histidine kinase
Homologs in the searched genomes :   46 hits    ( 46 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
ATGCAGACAACAGAAGAAATGCAATCTGGCGATGGACGCCGAGGTCGATTGCGGATATTTTTTGGATTTGCGGCTGGTGT
TGGGAAAACCTACGGTATGTTGACAGAGGCTCATGAATTATTGATGATGGGAAAACATGTTGTTGTCGGCTATATCGAAC
CTCATGATCGTCCAGATACCAATCGATTATTAGAAGGATTACCGCAAATTCCTCCTAAGAATATTTTTTATAAACAAATG
GTTTTAACAGAGCCGGATATTGATCAAATCATTCAACAGAAGCCCGAAATCGTGTTGATTGATGAACTGGCTCATTCCAA
TGCGGAAGGTTCTCGAAATCGTAAACGATACCAGGATATTGATGAACTGTTGAATGCAGGAATCGATGTTTTTACTACGG
TCAATGTTCAACATATCGAAAGTTTGAATGATATCGTTGAAGAAGTTACCGGAATTGAGGTCAAGGAAACGGTGCCGGAC
ACTTTTCTACGGCAAGCGACAATAAGAGTGATTGATGTGGAGCCCGATGAGCTGATCGAACGACTTGAACAAGGAAAAAT
ATATGCGAATGAAAACGCGAAACGTGCCTTGAAAAATTTTTTTATTCCACAAAAATTGGACCAATTACGTGGATTAGCAA
TTCAGCGAGCGTCGGATCATATTAATCGAATTAGTGGAAAGACAATTGGGATACAAAGTAAATTATTGACGGTGGTGAAC
GATGCCTTTCCAAAAATGACCGAAAAATGTATTCGCTGGACAGCACGTTTAGCGCAAGGTCTAGTTGTCGATTGGACAGT
GATTCAAGTTCGTACGCAAGAAAATACACCAACGAACATTCCTTTAGCCGATAAATTAGGTGCGGAGGTTATTAGTATTG
AAGAGGATGATAGTTTTGAGACGATTGTCGAGTTCGCAAAAATGACGGGTGTTACTGATATTATTATGGGGAAAAATCTA
AGGCAGCCGTGGTATGAAAAAATCTTTATTGAAGCGTTTGATGATCGCTTGTTAAAACGATTGAAAGATACGGAACTTCA
TTTAATTCCTTTCAATGAAGAAAAGCGGTCTTTATTTTTTAAGACTCGTAAAGTCATTGAGGGTGGCGGAAAAGATTTAG
TGATTGCAATTGGTGGTGTTTTTCTAGCGACGGTCGTGACGGAATTGATGCAATATATCCACGTTGGCGATCAAAATCTG
ATGCTTATTTATATTTCATTCGTATTATTAGTCGCTCGAACGACATCCGGTTATTTTTGGAGCTCATTATCCTCTATTTT
AAGTGTTTTGTCTTTTAACTGGTTTTTTGTCGAACCATTATATTCTCTGACAGTATATAAACAGGGATATCCTTTTACTT
TATTGCTCATGCTAGTTGTTGCCCTGATGAGCAGTAATTTAATGATTCGATTAAAGAAACAAGCAGATACTTCTATGAAA
AAAGAGCACCAAATGGAAATTTTGTACGAATTGAACAAACGATATGTTTTAGTGGAAAGTCGAAAACAAATTCTTGATAT
TTCTGCCACTTATTTATCAAGATTATTGGAACGAGAAGTGATTATTTTTGATCGTCAAGTGAAGACAGAGAGTGTTCATT
GTATCAACGAAAAAAAATCAATATTAAATAATGAAGACGAAGCAGCTGTAGCCTTTTGGGCAGCAAAGAACCAAAAAGAA
GCTGGGAATGGTACAGACACACTAAATGGAGCTAAAGGATTCTATTTGCCGATTGCTGCAGGCAGGAAGACGTTGGCGGT
ATTAGGCATTGAACGAAATGCAGATCTTGATTTGGAAAATGATCAGCTCAATTACTTAAAATTGGTGCTGACTCAAATTG
CGGTCATCTTGGAACAAACAGAATTGAAAGATGAGAAAGAGCAAGTTGAGTTAGAAAATGAACGGGAAAAAGTCCGCAGC
AATTTATTACGAGCCGTATCTCATGATCTGAGAACACCATTAACTGTTATCTCAGGGATTGCTGAAACATTAGGCATTGG
AAATGATTTAAAAGAAGAGACACAGCGAAAATTATTAAAGGATATTCAAGAAGAGTCACAATGGCTGATTCGGATGGTTG
AAAATCTTTTATCCATCACGCGAATCAACATGGATACTATGAAGGTTAATAAAACTGCTGAACCAGTAGAAGAGGTCATC
GAGGCTGTTTATAAGCATTTGAGGAAGGTCTATCCAGACGGCCAAGTGGATATTCACCTGCCAGAAGAGGTCATTTTTAT
TCAAGCGGACCCCATTTTGATTGAACAAGCGTTGTTTAATCTGATAGAAAATGCGTTTCGTCATGGAGAAAATGATCTAC
CAGTCAAACTAAACGTCTATCAGGAAAAAGAACAAACAGTTTTTGAAATTGAAAATCACGGCGAAATTCCATTAAAACAA
TTTCAAAAGATCCAATCAAACTTGTCCGGCACAAATGAAGTACCGGTTGACTCAAAAAATGGTTTAGGAATCGGATTGAG
TATTGTAAAAACAATCGTCCATGCGCACAATGGTAAAATGGAAATGACGATAGGTAGGGGCAAAACATTGGTTCGAATTT
ATTTGAAGTGA

Protein sequence :
MQTTEEMQSGDGRRGRLRIFFGFAAGVGKTYGMLTEAHELLMMGKHVVVGYIEPHDRPDTNRLLEGLPQIPPKNIFYKQM
VLTEPDIDQIIQQKPEIVLIDELAHSNAEGSRNRKRYQDIDELLNAGIDVFTTVNVQHIESLNDIVEEVTGIEVKETVPD
TFLRQATIRVIDVEPDELIERLEQGKIYANENAKRALKNFFIPQKLDQLRGLAIQRASDHINRISGKTIGIQSKLLTVVN
DAFPKMTEKCIRWTARLAQGLVVDWTVIQVRTQENTPTNIPLADKLGAEVISIEEDDSFETIVEFAKMTGVTDIIMGKNL
RQPWYEKIFIEAFDDRLLKRLKDTELHLIPFNEEKRSLFFKTRKVIEGGGKDLVIAIGGVFLATVVTELMQYIHVGDQNL
MLIYISFVLLVARTTSGYFWSSLSSILSVLSFNWFFVEPLYSLTVYKQGYPFTLLLMLVVALMSSNLMIRLKKQADTSMK
KEHQMEILYELNKRYVLVESRKQILDISATYLSRLLEREVIIFDRQVKTESVHCINEKKSILNNEDEAAVAFWAAKNQKE
AGNGTDTLNGAKGFYLPIAAGRKTLAVLGIERNADLDLENDQLNYLKLVLTQIAVILEQTELKDEKEQVELENEREKVRS
NLLRAVSHDLRTPLTVISGIAETLGIGNDLKEETQRKLLKDIQEESQWLIRMVENLLSITRINMDTMKVNKTAEPVEEVI
EAVYKHLRKVYPDGQVDIHLPEEVIFIQADPILIEQALFNLIENAFRHGENDLPVKLNVYQEKEQTVFEIENHGEIPLKQ
FQKIQSNLSGTNEVPVDSKNGLGIGLSIVKTIVHAHNGKMEMTIGRGKTLVRIYLK