PAI Gene Information


Name : ef0048
Accession : AAM75253.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Virulence
Product : EF0048
Function : -
Note : CylA; cytolysin activator
Homologs in the searched genomes :   No hits  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
ATGAAAAAAAGAGGATTGACTTATATTTTAATCTCATATATTTTTTTAATATTAGGAACAACAGGTTATGCATCAGATCT
CTCAAATAATATTTCATTTTTTATTGATAATTCGCAAACAACTGCTATAGAAGAAATTGAGTCTGAATTATCTTCTGAAA
AAGTAGATTATATACAGGAAATAGGATTAGTTAGTTTTAAAAACCTGGATGATAGTGATAGGAAGTTTATAGGTAAATAT
TTTAATGTTTCGGAAGGGAAAAAATTACCAGATTTTAAACCTGAAGAAGTTAATAGTTCTATTTTAAACATTAATATTTT
AAACAAAGATTTTAAGTCTTTTAATTGGCCATATAAAAAAATTTTATCTCATATTGATCCAGTGAAAGAACAACTAGGGA
AAGATATAACCATAGCTCTAATTGACTCGGGGATTGATAGGCTTCATCCTAATCTTCAAGACAATAACCTAAGATTAAAA
AACCATGTTAATGATATTGAGTTAGATGAATATGGTCATGGTACACAAGTTGCTGGAGTAATAGACACGATTGCTCCAAG
AGTAAATTTAAATTCTTATAAGGTGATGGATGGGACAGATGGAAACTCTATAAATATGCTTAAAGCTATAGTTGATGCTA
CAAATGATCAAGTAGATATAATAAATGTGAGTCTTGGATCATATAAAAATATGGAAATAGACGACGAAAGATTTACTGTA
GAAGCATTCAGAAAAGCTGTTAACTATGCAAGAAAAAATAACATTCTAATTGTTGCATCAGCAGGAAATGAGTCGCGTGA
TATAAGCACTGGTAATGAAAAACATATACCAGGAGGACTAGAGTCTGTAATTACCGTCGGAGCTACAAAAAAGAGTGGTG
ATATTGCTGACTATTCTAATTATGGGTCTAATGTATCTATATATGGTCCTGCAGGAGGATATGGTGACAATTACAAAATA
ACAGGACAAATTGATGCTCGTGAAATGATGATGACTTATTACCCTACATCGCTAGTTTCTCCACTAGGCAAAGCTGCTGA
CTTTCCAGATGGTTATACACTTTCTTTTGGAACAAGTTTAGCAACTCCAGAAGTAAGCGCAGCTTTAGCAGCTATTATGT
CAAAGAATGTAGATAATTCTAAAGATTCAAATGAAGTATTAAATACTTTATTTGAAAATGCTGATTCTTTTATAGATAAA
AATAGCATGCTTAAATACAAAGAGGTGAGAATAAAATAG

Protein sequence :
MKKRGLTYILISYIFLILGTTGYASDLSNNISFFIDNSQTTAIEEIESELSSEKVDYIQEIGLVSFKNLDDSDRKFIGKY
FNVSEGKKLPDFKPEEVNSSILNINILNKDFKSFNWPYKKILSHIDPVKEQLGKDITIALIDSGIDRLHPNLQDNNLRLK
NHVNDIELDEYGHGTQVAGVIDTIAPRVNLNSYKVMDGTDGNSINMLKAIVDATNDQVDIINVSLGSYKNMEIDDERFTV
EAFRKAVNYARKNNILIVASAGNESRDISTGNEKHIPGGLESVITVGATKKSGDIADYSNYGSNVSIYGPAGGYGDNYKI
TGQIDAREMMMTYYPTSLVSPLGKAADFPDGYTLSFGTSLATPEVSAALAAIMSKNVDNSKDSNEVLNTLFENADSFIDK
NSMLKYKEVRIK