PAI Gene Information


Name : ef0021
Accession : AAM75227.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : EF0021
Function : -
Note : conserved hypothetical
Homologs in the searched genomes :   3 hits    ( 3 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
GTGCCATTAAAAAGTAAAGAGCCGCGCTTAGACTTTCCAATTGAAGCCATTACGAATAATTTTCTTTTTACAACCTCTAA
CGACGTGTGGGTAGGTTATAAACTTGCACACCAAGTATTTCCTTTGAATAATTTAGACTTTTTCAAGGAATACATAGAGG
ACGGAAAAGGCGTATTCGAGCAAGACACGTTCGACTACCATTTTATGAATATTCCAGAATACTTTGATCTCGACGAACAG
ATTGAAGCGACAATCGATAACCTGGTAAAGGGAAGCTTTGCGGATTTAGGAGAAACCTATTTCCGACAAGCGGGTGATAT
TCTAAAAGACGAAGTCCAAATGAATAAATATAGTACGTATTTGTTCATTCGTTTTACCGCACCTATACAAGTTGCTAATC
CTATGGAGTATATAGAATTGTTCAAGGAAGTTGGACGTAAGGCAATCAATGCTTTAACAGGGGTTCATGTACCAGTTAGC
CAACTTTATCGCGCATATCAAGGATTAGAAAACAAGATTTACAAAGACTTATCAAATTTTAAAAATGTGGAACGCATGGA
TCCAAGAACCATAGGTCGATTGTTTTATTATTTCTTTCACCGTGCAAATACCCGTTTACCTGAACGAACGTTACTTCCGG
AAGAAATGACGGAGGGGATTATTGAAAATAACACGGGATATATGACTATTGAACAATTGGATAAAACACATTACCTTGCT
TTTTTACCGTTGATCAGTTTGCCAACGAGTATGTTTGGAAGTGCGATTATACAAAACTTGCAGGATAGTTTGAGTACCAC
GATTGAAACCCATGTCAAGGTTACATTTCGCCACCCAGATAAAGATAAACGCGATGTACACAAACGTCGTAAAAGAATCT
ATGAACAGGACAAAGAGCAAACACAAGTTGACGGTATTTTAGACGAAGACGAAGTGATTTTATTTGGGGAAGAGCGATTG
CACGAACTAAGTAAAAAGATACGTAGTAAAGAACGACGATTGTGTCGTATGACGACAACGTTTGTACTTTCAGCCGATAG
TAAACAAGCATTAGAAGAGAAAATAAAAGAACTCGAATTTGTTTTGGACGGTACAGACTACAAGTTGTATCGTCCGCTAG
TCGACCAATTAACATTGTTTAATCAGTGTTTAATTGGCGCTAAGAGTCAATTTAAAAGCTATGAGCATGTTGTTTCAACA
GGTTATGTAGCGGACCTTGGAATGGATTTAGAAAAAGAAATTGGTAACCGCTATGGCATGCCTCTAGGTCGTGTCATAAC
TGCTAAAAAATTCAAGTCCGTACAACAGGCACTTTCTTTATCAAGCAAAATCGTATGGTTTTTCCCAAACTTGACTAAAA
AAGCCATAGAAGGCGCACAATATACAAATGGGAATACGCTAATCATTGGCCCGCCTGGGCAAGGAAAGTCAGTACTTGTT
AAGTACATTTTCTTGTGGTTAACGTTTTTAGGACAAAAAATACTTTATATTGATCCTAAAAATGAAACCGTCCTTTTTTT
CAAACGAGCATTAGATAAGTTCGGACATATTCCAGAATTTAAAGCTTTGTATCAACGCATTAACTTTGTTTCGCTATCAA
GTGAAGAAAGGTATCGAGGAATGTTAGATCCATTGCTATTTCTGCCAAGAGAAGAAGCTATTCAAACCGCACGAAACGTG
TTAGAAAATTTTGGTGAAGTTACGACAGACAGTCACACTGCAAGTGATAAGAAGACGCTGATTTTAGATTCTGTCAATGC
GGTGATGAAAGGTAAAGGGAAAAAACACCTAACGAAAGTAATCGAGGTTATTCGCGAAAAAGACCCTAAATTAGCAAATT
TAATCTCTGGCCACAATGTTGGGTTAGGCAAAATTCTTTTAGGGAACGATTACAGCGAACCTATTCGCTTTGAAAATCAA
ATCAATGTCTTAGGTACCCAGGGGCTTAAAATCCCTACACAAGCGGAAATAGACAGCGGACGATTAAACAATGAACAAAT
CGCAGGCATGTCTATTATGGAAGTTATTATGAAAATGACAACGATCTTCTCTACAGATAAAACTGAAGATGCTGCGATTA
TTTTCGATGAAGCGAAAGGATTTGAAGACACGGCCCAAGGACGTTTTCTAATTGAAGGAAGTTTACGCCAAGGACGTGCG
AACATGACCGATATATACCTTGTCACACAAGCGTTTATGGATTATGATAAAGAAGATAAAAAAGAACTATTGTCTTATAA
ATTTGCGTTCCGGCCAAACCAAAAAGAAGCACAGAAAAAAGTTTTAGAATTTTTTGGTATGGATACGAACCCAGCAAATA
TTCAGTTAATTAATGAACTAAAATCAGGGACTTGTTTATTCCAAGACCATCGAGGGCGTAGCCAGCCTATTGCAATTGAT
GTTTTATTCGATAGTTGGTTAATGGCCGTTTCGTCTACTAATAAAGAGGATGAAGCTACTCAAATGGCGTTGGCAATGGA
ACAAGGATCATAA

Protein sequence :
MPLKSKEPRLDFPIEAITNNFLFTTSNDVWVGYKLAHQVFPLNNLDFFKEYIEDGKGVFEQDTFDYHFMNIPEYFDLDEQ
IEATIDNLVKGSFADLGETYFRQAGDILKDEVQMNKYSTYLFIRFTAPIQVANPMEYIELFKEVGRKAINALTGVHVPVS
QLYRAYQGLENKIYKDLSNFKNVERMDPRTIGRLFYYFFHRANTRLPERTLLPEEMTEGIIENNTGYMTIEQLDKTHYLA
FLPLISLPTSMFGSAIIQNLQDSLSTTIETHVKVTFRHPDKDKRDVHKRRKRIYEQDKEQTQVDGILDEDEVILFGEERL
HELSKKIRSKERRLCRMTTTFVLSADSKQALEEKIKELEFVLDGTDYKLYRPLVDQLTLFNQCLIGAKSQFKSYEHVVST
GYVADLGMDLEKEIGNRYGMPLGRVITAKKFKSVQQALSLSSKIVWFFPNLTKKAIEGAQYTNGNTLIIGPPGQGKSVLV
KYIFLWLTFLGQKILYIDPKNETVLFFKRALDKFGHIPEFKALYQRINFVSLSSEERYRGMLDPLLFLPREEAIQTARNV
LENFGEVTTDSHTASDKKTLILDSVNAVMKGKGKKHLTKVIEVIREKDPKLANLISGHNVGLGKILLGNDYSEPIRFENQ
INVLGTQGLKIPTQAEIDSGRLNNEQIAGMSIMEVIMKMTTIFSTDKTEDAAIIFDEAKGFEDTAQGRFLIEGSLRQGRA
NMTDIYLVTQAFMDYDKEDKKELLSYKFAFRPNQKEAQKKVLEFFGMDTNPANIQLINELKSGTCLFQDHRGRSQPIAID
VLFDSWLMAVSSTNKEDEATQMALAMEQGS