PAI Gene Information


Name : ef0012
Accession : AAM75218.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : EF0012
Function : -
Note : conserved; IepA-like protein
Homologs in the searched genomes :   39 hits    ( 39 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
ATGAATCAAAACCTTTTAGAAAAAACGCCCAAAAATAATAAGTTAAGATATGCAGAATATTATGGCATGATTGAAATTTA
TGACGAACTGTTCAATAAAAGTAATGAAGGTAAAATTTTCAAGAATTTAATGGGGATAATTATCTCAACAGATAACATTT
TGTTAGCCTACCGAACCATAAAAAGGAACGGAGGGAGCACAACAAAAGGAATCGATGGAGTAACCGTAAAAGACATTGAA
AAACTATCTCAATCAGAGTTTATTGGAAAAGTTCGAAATAGATTCAATTTCTACAAACCTAGAAAAGTCAGAAGAGTAGA
AATTCCCAAACCGAACGGGAAAACTAGACCCTTAGGGATTCCTTCAATTTGGGACAGAATCGCTCAGCAATGTATTTTAC
AAGTATTAGAACCAATTTGCGAAGCCAAGTTTAATAAACATAGTTATGGATTTCGACCCTTAAGGTCTACAGATAACGCC
ATAGCTGACTGTCTGTCTAATCAATTAAAAGTCATATGCCATATTGTAGGTAGGATTTTGATATTCAAGGATTTTTCGAT
GCAGGGGAATCATGTGAAAACTAATGCCGACAAATTTCGGCCATTTCGGAATTCGAGGATAAAAAAGCTTTTTCTTTTTC
TTACGGGAAAATGTTTAAAAGCCCCCTTTGGTTTTACCAGAACGGCCCTTTTTTTAAAATTTCCAACTAAGGGGACCCCC
CAAGGAGGAATACTCTCCCCACTTTTATCAAATATTTGTTTAAACGAGTTTGATTGGTGGATTGCCAGGCAATGGGAAGA
ACGAGAATGTAGCGAGCTTGTTCCACAATTTAACTCAAAGGGCACAAGACATAAATCACATGATTACAGAAAACTTCGTT
CATCAACGACTCTAAAACAAGTGTATATCGTAAGGTATGCAGATGATTTTAAGTTGTTTTGTAAGATCGACAGGAGGCTG
AAAGACTCTTCCGGTGCCACGAAAATGTGGCTGAAAGAACGATTAAGGCTACCAATCTCAGAAGAAAAGTCGAAAGTAAC
AAACTTGAAAAAGAAAAGTAGTGAATTCTTAGGGATTACATTGAAAATGGTCAAAAAGAACCATCGGTTCGTCTGTTACT
CTCACGTTGCCCTAAAGGCAAGAAAGAGAATCAAACGACAACTAAAGGATCAAATTAAACGGATCCAAAGAAAGAAAAGT
AAAATCACTACTATTAGAGAAATCCAAAAATACAACAGTATGGTTATAGGCATTCATAATTATTACAACGTGGCAACACA
TGTATCCAAGGATTTTGAATCGATAGGGTCACAACTGCATAGAAGTTTTTACAACCGATTCAGAAATAAAGGATTGACCA
AAAAGGGAAATTACAAGGGACATGATAAAGGGATTCAACCTTATATGGAATCAAAAAGAATTCAATATCTAGTAAACTTT
CCCCCATTCCTTCCAAATAGGATTTGGAAGAACCAAAACCCATCCAAAGGGAGAAAAAAAACTCTTAATAAATACACCGC
CCTGAAGGTCGGAAACTTGTACACAAAAATCAACAATCCTGTAGCAGAATGGAAAGTCCAATGGTTACGAGAACATCCAA
TTATTAATGAAAGAGCAACCATTGAATATAATGATAACCGAATTTCGTTATTCATTGCGCAAAAAGGAAAGTGTGCTATT
ACAGGTAACGAATTATTTCTTGACGATATGCATTGTCACCACAAGAAACTATGGTCAGAAAGTAAAGACGATTCATATAA
AAATTTGATTTTACTTTCAAAAGAAATGCATAAATTGGTGCATTGTACCGATGAAGTAAAAATAAGAGAGTATATTTATT
GGAATAAATTGTCAGATTCACAAGTAAATAAAGTAAATAAACTTAGAAAGCTTGTAAATAAAACAATCATTCTTCCATTA
TGCGAACAGATGCCCAAATATGAGCAATTAACACTTTTCTAA

Protein sequence :
MNQNLLEKTPKNNKLRYAEYYGMIEIYDELFNKSNEGKIFKNLMGIIISTDNILLAYRTIKRNGGSTTKGIDGVTVKDIE
KLSQSEFIGKVRNRFNFYKPRKVRRVEIPKPNGKTRPLGIPSIWDRIAQQCILQVLEPICEAKFNKHSYGFRPLRSTDNA
IADCLSNQLKVICHIVGRILIFKDFSMQGNHVKTNADKFRPFRNSRIKKLFLFLTGKCLKAPFGFTRTALFLKFPTKGTP
QGGILSPLLSNICLNEFDWWIARQWEERECSELVPQFNSKGTRHKSHDYRKLRSSTTLKQVYIVRYADDFKLFCKIDRRL
KDSSGATKMWLKERLRLPISEEKSKVTNLKKKSSEFLGITLKMVKKNHRFVCYSHVALKARKRIKRQLKDQIKRIQRKKS
KITTIREIQKYNSMVIGIHNYYNVATHVSKDFESIGSQLHRSFYNRFRNKGLTKKGNYKGHDKGIQPYMESKRIQYLVNF
PPFLPNRIWKNQNPSKGRKKTLNKYTALKVGNLYTKINNPVAEWKVQWLREHPIINERATIEYNDNRISLFIAQKGKCAI
TGNELFLDDMHCHHKKLWSESKDDSYKNLILLSKEMHKLVHCTDEVKIREYIYWNKLSDSQVNKVNKLRKLVNKTIILPL
CEQMPKYEQLTLF