PAI Gene Information


Name : aadA1
Accession : AAL08435.1
PAI name : SRL
PAI accession : AF326777
Strain : Shigella flexneri 2002017
Virulence or Resistance: Not determined
Product : streptomycin adenyltransferase AadA1
Function : -
Note : confers streptomycin and spectinomycin resistance; similar to AadA1 from Tn21 on plasmid R100
Homologs in the searched genomes :   109 hits    ( 109 protein-level )  
Publication :
    -Luck,S.N., Turner,S.A. and Rajakumar,K., "Direct Submission", Submitted (06-DEC-2000) Microbiology, Monash University, VIC 3800, Australia.

    -Luck,S.N., Turner,S.A. and Rajakumar,K., "Direct Submission", Submitted (17-MAY-2002) Microbiology, Monash University, VIC 3800, Australia REMARK Amino acid sequence updated by submitter.

    -Luck,S.N., Turner,S.A. and Rajakumar,K., "Direct Submission", Submitted (18-JUN-2002) Microbiology, Monash University, VIC 3800, Australia REMARK Sequence update by submitter.

    -Luck,S.N., Turner,S.A. and Rajakumar,K., "Direct Submission", Submitted (19-JAN-2005) Microbiology, Monash University, VIC 3800, Australia REMARK Sequence update by submitter.

    -Luck,S.N., Turner,S.A., Rajakumar,K., Sakellaris,H. and Adler,B., "Ferric dicitrate transport system (Fec) of Shigella flexneri 2a YSH6000 is encoded on a novel pathogenicity island carrying multiple antibiotic resistance genes", Infect. Immun. 69 (10), 6012-6021 (2001) PUBMED 11553538.


DNA sequence : 
ATGAGGGAAGTGGTGATCGCCGAAGTATCGACTCAACTATCAGAGGTAGTTGGCGTCATCGAGCGCCATCTCGAACCGAC
GTTGCTGGCCGTACATTTGTACGGCTCCGCAGTGGATGGCGGCCTGAAGCCACACAGTGATATTGATTTGCTGGTTACGG
TGACCGTAAGGCTTGATGAAACAACGCGGCGAGCTTTGATCAACGACCTTTTGGAAACTTCGGCTTCCCCTGGAGAGAGC
GAGATTCTCCGCGCTGTAGAAGTCACCATTGTTGTGCACGACGACATCATTCCGTGGCGTTATCCAGCTAAGCGCGAACT
GCAATTTGGAGAATGGNAGCGCAATGACATTCTTGCAGGTATCTTCGAGCCAGCCACGATCGACATTGATCTGGCTATCT
TGCTGACAAAAGCAAGAGAACATAGCGTTGCCTTGGTAGGTCCAGCGGCGGAGGAACTCTTTGATCCGGTTCCTGAACAG
GATCTATTTGAGGNGCTAAATGAAACCTTAACGCTATGGAACTCGCCGCCCGACTGGNCTGGCGATGANCGAAATGTAGT
GCNTACGTTGTCCCNCATTTGGNACAGCNCAGTAACNGNCAAAATCGCGCCGAAGGATGTCNCTGCCGACTGGGCAATGG
AGCGCCTGCCGGCCCAGTATCAGCCCGTCATACTTGAAGCTAGACAGNCTTATCTTGGACAAGAAGAAGATCGCTTGGCC
TCGCGCGCAGATCAGTTGGAAGAATTTGTTCACTACGTGAAAGGCGAGATCACCAAGGTAGTCGGCAAATAA

Protein sequence : 
MREVVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDIDLLVTVTVRLDETTRRALINDLLETSASPGES
EILRAVEVTIVVHDDIIPWRYPAKRELQFGEWXRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
DLFEXLNETLTLWNSPPDWXGDXRNVVXTLSXIWXSXVTXKIAPKDVXADWAMERLPAQYQPVILEARQXYLGQEEDRLA
SRADQLEEFVHYVKGEITKVVGK