PAI Gene Information


Name : int
Accession : AAK16198.1
PAI name : PAI-I AL862
PAI accession : AF072900
Strain : Escherichia coli 042
Virulence or Resistance: Not determined
Product : Int
Function : -
Note : similar to prophage P4 integrase
Homologs in the searched genomes :   537 hits    ( 536 protein-level,   1 DNA-level )  
Publication :
    -Lalioui,L. and Le Bouguenec,C., "afa-8 Gene cluster is carried by a pathogenicity island inserted into the tRNA(Phe) of human and bovine pathogenic Escherichia coli isolates", Infect. Immun. 69 (2), 937-948 (2001) PUBMED 11159989.

    -Lalioui,L. and Le Bouguenec,C., "Direct Submission", Submitted (19-JUN-1998) Path. Bact. des Muq., Institut Pasteur, 28 rue du Dr. Roux, Paris Cedex 15 75724, France.

    -Lalioui,L. and Le Bouguenec,C., "Direct Submission", Submitted (01-JUL-1998) Path. Bact. des Muq., Institut Pasteur, 28 rue du Dr Roux, Paris cedex 15 75724, France.

    -Lalioui,L. and Le Bouguenec,C., "Direct Submission", Submitted (03-AUG-1999) Path. Bact. des Muq., Institut Pasteur, 28 rue du Dr. Roux, Paris Cedex 15 75724, France REMARK Sequence update by submitter.

    -Lalioui,L. and Le Bouguenec,C.C., "Direct Submission", Submitted (02-AUG-2000) Unite de Pathogenie Bacterienne des Muqueuses, Institut Pasteur, 28 rue du Dr Roux, Paris Cedex 15 75724, France REMARK Sequence update by submitter.

    -Lalioui,L., Jouve,M., Gounon,P. and Le Bouguenec,C., "Molecular cloning and characterization of the afa-7 and afa-8 gene clusters encoding afimbrial adhesins in Escherichia coli strains associated with diarrhea or septicemia in calves", Infect. Immun. 67 (10), 5048-5059 (1999) PUBMED 10496877.


DNA sequence : 
ATGGCACTGACTGACGCAAAAATCCGGGCTGCAAAGCCCACTGACAAGGCTTATAAACTCACTGACGGGGCCGGCATGTT
CCTGCTGGTTCATCCTAATGGTTCCCGTTACTGGCGTCTCCGTTATCGTATTCTGGGTAAGGAGAAGACTCTGGCACTTG
GTGTGTATCCAGAAGTTTCTCTCTCCGAAGCTCGTACAAAACGGGATGAGGCCCGAAAACTGATTTCAGAGGGGATTGAC
CCTTGCGAACAGAAAAGAGTTAAAAAAGTAGTCCCTGATTTACAGCTCTCTTTTGAACATATTGCACGACGCTGGCATGC
CAGTAATAAACAATGGGCACAATCACACAGCGATAAAGTACTCAAAAGCCTCGAGACACACGTTTTCCCCTTTATCGGCA
ACCGGGATATCACAACACTCAATACCCCGGACCTGCTTATTCCTGTTCGTGCTGCAGAAGCAAAACAAATTTATGAAATC
GCCAGTCGGCTGCAGCAAAGAATATCTGCTGTAATGCGTTACGCCGTACAGTCTGGCATCATCAGATATAACCCGGCTCT
GGATATGGCTGGTGCATTGACCACGGTAAAACGCCAGCATCGCCCCGCTCTGAATCTTTCACGCCTGCCTGAACTTCTGT
CGCGTATTGACGGTTATAAAGGCCAGCCTGTCACCCGGCTTGCCGTTATGCTGAATTTACTGGTTTTTATTCGTTCCAGT
GAACTCAGATATGCCCGCTGGTCTGAAATTGATATTGACAATGCCATGTGGACTATTCCAGCCGAACGCGAACCTCTGCC
TGGCGTAAAATTCTCACACCGGGGCTCTAAGATGCGAACACCACATCTTGTGCCACTCAGCAAACAGGCTGTAGCCATAC
TGACAGAACTTCAGACATGGGCTGGTGAAAATGGTCTGATCTTTACGGGAGCACATGACCCGCGTAAACCAATCAGTGAA
AATACTGTAAATAAAGCCCTGAGGGTGATGGGATATGACACAACCCGGGAAGTCTGTGGCCATGGATTCCGGGCGATGGC
ATGCAGTGCATTGATTGAATCAGGTTTGTGGTCCCGCGATGCAGTGGAACGTCAGATGAGTCATCAGGAGCGTAATGGTG
TACGTGCTGCGTATATCCATAAAGCAGAACATCTGGAAGAACGTCGACTGATGCTACAGTGGTGGGCAGATTTTCTGGAT
GCAAACAGAGAAAGATTTATCAGTCCATTTGAATATGCAAAGATTAATAACCCATTAAAACAGTAA

Protein sequence : 
MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRILGKEKTLALGVYPEVSLSEARTKRDEARKLISEGID
PCEQKRVKKVVPDLQLSFEHIARRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALNLSRLPELLSRIDGYKGQPVTRLAVMLNLLVFIRSS
ELRYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGSKMRTPHLVPLSKQAVAILTELQTWAGENGLIFTGAHDPRKPISE
NTVNKALRVMGYDTTREVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLMLQWWADFLD
ANRERFISPFEYAKINNPLKQ