Name : fgtA
Accession : AAK15339.1
PAI name : Not named
PAI accession : AF332547
Strain : Pseudomonas aeruginosa B136-33
Virulence or Resistance: Virulence
Product : flagellar glycosyl transferase
Function : -
Note : similar to O-antigen biosynthesis protein RfbC of Myxococcus xanthus; attaches first sugar molecule to the flagellin protein
Homologs in the searched genomes : 26 hits ( 26 protein-level )
Publication :
-Arora,S.K., Bangera,M., Lory,S. and Ramphal,R., "A genomic island in Pseudomonas aeruginosa carries the determinants of flagellin glycosylation", Proc. Natl. Acad. Sci. U.S.A. 98 (16), 9342-9347 (2001) PUBMED 11481492.
-Arora,S.K., Lory,S. and Ramphal,R., "Direct Submission", Submitted (28-DEC-2000) Medicine/Infectious Diseases, University of Florida, R2-148, ARB Building, 1600 SW Archer Road, Gainesville, FL 32610, USA.
-Schirm,M., Arora,S.K., Verma,A., Vinogradov,E., Thibault,P., Ramphal,R. and Logan,S.M., "Structural and genetic characterization of glycosylation of type a flagellin in Pseudomonas aeruginosa", J. Bacteriol. 186 (9), 2523-2531 (2004) PUBMED 15090491.
-Verma,A., Schirm,M., Arora,S.K., Thibault,P., Logan,S.M. and Ramphal,R., "Glycosylation of b-Type flagellin of Pseudomonas aeruginosa: structural and genetic basis", J. Bacteriol. 188 (12), 4395-4403 (2006) PUBMED 16740946.
| DNA sequence : | |
ATGATTCCCAAAGGCAAGGCCCGACAGAGACTAGCCTGGCGAATCGATGCTCTTCAATTTCGACAACGGTCAATGAATAT
GGGTGAACAGGCTCTCGTCAGCATCGTCATGCCGACCTACAAGCTGGAGTACTTCGAGGACGCCCTCGACAGCGTGCTCG
GGCAGACCTATCCGGCCCTGGAGCTGATCATCTGCGACGACAGCAGCGACGAGCGGATCGCCACGCTGGTCGAGCAGAAG
CGCGCCTCCGCGGCATTCCCGATCCGCTACTTCCGCAACGAGACGCGCCTCGGCGAGCTGGGCAGCACGGCGAAAGGCAT
CCGCCTGGCGGAGGGCGAGTACGTCAAGTTTCTCCAGGACGACGACGTGTTGCTTCCCGAATGCGTCGAGACGTTGGTGG
GAGCGATGGAGCGCGAGCCGAACGTGGTCCTGGCCTCGTCGCGGCGGTTGCGTATCGACGAGGAAGGGCAGCCGCTGCCG
GACATCCTGGCGACCTGCTTCCCGTTCGCCGGCGACGTCCTGATCGACGGTCGCGAGCTGGTCTCGTTCCTCGCCGACCA
CACCATCAACTTCATCGGCGAACCCAGTTGCCTGATGGCCCGGCGCGATGCGCTGCTGCAGATCTGCGAGCGCCTGATGA
TGCTCAACGGCCGGGCCATCGACTGGATCGGCGACCTGGCCATGTGTGCGCAGTTGCTACAGCGTGGCGACCTGGCGTTC
CTGTCGCGGCCGCTGACCCGTTTCCGCGTCTCCCGCCAGCAGTTCAGCCAGATCGGGCGCGACCAGCCCGGTATCGGCGA
GCAGGGCCATGCCGACTTCCGCTTGGCTATCCGCGAACTGGGTTGGTATCGCCAGGCCGGCGACAACCGTTTCGTCCGGG
TGGCACCGATCACCCGCCTGGACGCCCGTGTCTTCAAGCCTGTCAACCTGCTCGCCGCGCTGAGGCGGGCGGCGGGCTTC
GGTAGCGTCACGCTGTCGACCTGGCTGGAGGCGCGGCGGCCGGATGCGGTGCAGAAGGCGCTGATCGATCGATTCCTGCA
GGAGCAGGGCGGTGGGCCGCGCTTCGCGGTGCTGGTGCTCGACACCCACGGCGATACCGAGGCCGTGGAGCGCACCCTGC
AGAGCCTGGAGCACGTCAATTCGTATCCACATGTCGAGAGCCACCTGTTCGCGCCGCTGGGCGCGAGTCCGCGGAACGGA
GCGATGCTCTTCGATCCTGCCGCGGGGCCGATACGGACGATCAACCAGGCGCTTGCCCGGCTTGATACCGACTGGTTGCT
CCTGGTCGAAGCGGGCGTCGAATTCACTGTCAGCGGCCTGCTGGTGGCGGCGCTGGACCTGCTGGCGGCACCGGAGAGCT
GCCAGGCGGTGTACGCCGACGAACTCATGCGCCTGGATGACGGCGAGCTGGGCGCGGCGTTGCGCCCGGACCTGAATCTC
GACCTTCTGCTCAGTTTCCCCGCCGGCCTGTCCCGGCACTGGTTGTTCCGCCGCGAGCCGCTGCTTGCCACGGGCGGATT
CGACGAGACCGCCGGCGAGGCTTTCGAGCTGGCCTACCAGTTGCGTCTCGTCGAGCAGCGGGGCCTGGGCTGTATCGGAC
ACATCAGCGAGCCACTGCTGTCTGGCCCAGCGCTGCGCCTGCAGGACAGCACCGCCGAGCGTGCGGCGATCGAAGGCCAC
CTGCGTGCCCGTGGCTACGCGCAGGCGACAGTCGGAAGCCGGCTGCCGGGGCGCTACGAGCTGGACTACGGCCACGCCGG
GCAACCGCCGGTCAGCATCCTGGTGCTGGCCGGGGAGCGCCTGGCGCAGCTCCAGCGTTGCGTAGAAACCGTGCTGGAGA
ATACCGCCTATCCCAACTACGAGATCCTTCTGCTGGAACAGGGTGGCGAAGCGGCCGACGTTCGCGAATGGCTGCTCGCC
GTCGAAGGCATGGGTGTCGAGCAGGTGCGGGTGCTGCGAGGCGATGGGCAGTTATCCCGTGGGGCTCTGCGCAACCTGGC
GGCGTCCCGGGCGCGTGGCGAATTCCTGCTCTGGCTCGATGCCGGCAGCGGCATCCTCGACAAGGACTGGCTGCAGCAGT
TGCTCAACCATGGCCAGCGTCCGGAAGTCGGCGCGGTAGGCGCCAAGCTCCTGGCGGCGGACGGACGGGTCTGCCACGCC
GGCTGGCTGCTCGGCTTATGCGGACCGGCCGGGCGGGCCTTCGAAGGGCGTTCGCACGAGGACGCCGGTTACCTGCAGCG
CCTGCAGGTGGACCAGAACTACTCGGCGGTGGCTGGCGAATGCCTGTTGATGCGCCGCGAGTTGTTTCTCGAATTGGGCG
GTTTCGACGAGGCGCTGACGCGCTGGGACGATGTCGACATCTGCCTGCGGGCGGTCCAGGCGGGCTACCTGAACGTATGG
ACGCCGCGTGCGCGGCTGTTGCTCGATGCGCCTGCCACGACGGCGGCGAGCGTCGAGGAAGAAGATGCGCTGTACACGCG
CTGGCTACCGTTGTTGGCACGCGATCCCGCCTATAACCCGGGCTTTTCGTTGCAGGCCGAAGGCGGTTTCAAGCTGGCCG
ACCCGCAGCTGGCCTGGCGCCCGTTGCAGGGGTGGCGGCCTTGCCCACTGTCTGGCGCACCCCGCCGACCTATTCGGCTG
CGGCCATTACCGGGTGATCCAGCCGTTCAGCACGTTGCGCGAGTCGGCATCCATCGATGGCGCGCTGTCGATCGGCCTGA
TGCACGTGGCCGATCTGGAGCGCTACGACCCGGACGTACTGGTGCTGCAGCGCCAGGTCGGCGAGGAGCGTCTCGAGGCC
ATGCGGCGGATGCAGGCGTTCTCGCGGGCCTTCAAGGTCTACGAGCTGGACGACTATCTGCCCAACGTGCCCCTCAAGAG
CGCCCATCGCCAGCACCTGCCGAAGGACATTTTGCGCACGCTGCGTCGCGGGCTGGGTTACGTCGACCGCTTCGTGGTGT
CGACGCCGGCCCTGGCAGAGGCCTTCGCCGGTCTCCACCCGGATATCCAGGTGATCGAGAACCGCCTGCCGGTGGGGTGG
TGGCAGGGGCTGCGGGCGCAGCGGCGGCGCGGCGAGCGGCCACGTGTCGGTTGGGCGGGCGGCTCGAGCCATACCGGCGA
TCTGGAACTGATCGCCGATGTGGTCCGGGAACTGGCCGACGAAGTCGACTGGGTGTTCTTCGGCATGTGCCCGCCGTCCA
TCCGTCCCTTCGTCAGGGAAGTGCATGCGGGGGTGCCTATCGAACGCTATCCGCGGGCATTGGCGGCTCTCGATCTCGAC
CTGGCGCTGGCGCCGGTGGAGCAGAACCTGTTCAACGAGTGCAAGAGCAATCTGCGCCTGCTGGAATACGGCGCCTGCGG
TTTCCCGGTGGTCTGCAGCGACGTGCGCTGCTACCAGGACGATCTGACCGGTGA
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| Protein sequence : | |
MIPKGKARQRLAWRIDALQFRQRSMNMGEQALVSIVMPTYKLEYFEDALDSVLGQTYPALELIICDDSSDERIATLVEQK
RASAAFPIRYFRNETRLGELGSTAKGIRLAEGEYVKFLQDDDVLLPECVETLVGAMEREPNVVLASSRRLRIDEEGQPLP
DILATCFPFAGDVLIDGRELVSFLADHTINFIGEPSCLMARRDALLQICERLMMLNGRAIDWIGDLAMCAQLLQRGDLAF
LSRPLTRFRVSRQQFSQIGRDQPGIGEQGHADFRLAIRELGWYRQAGDNRFVRVAPITRLDARVFKPVNLLAALRRAAGF
GSVTLSTWLEARRPDAVQKALIDRFLQEQGGGPRFAVLVLDTHGDTEAVERTLQSLEHVNSYPHVESHLFAPLGASPRNG
AMLFDPAAGPIRTINQALARLDTDWLLLVEAGVEFTVSGLLVAALDLLAAPESCQAVYADELMRLDDGELGAALRPDLNL
DLLLSFPAGLSRHWLFRREPLLATGGFDETAGEAFELAYQLRLVEQRGLGCIGHISEPLLSGPALRLQDSTAERAAIEGH
LRARGYAQATVGSRLPGRYELDYGHAGQPPVSILVLAGERLAQLQRCVETVLENTAYPNYEILLLEQGGEAADVREWLLA
VEGMGVEQVRVLRGDGQLSRGALRNLAASRARGEFLLWLDAGSGILDKDWLQQLLNHGQRPEVGAVGAKLLAADGRVCHA
GWLLGLCGPAGRAFEGRSHEDAGYLQRLQVDQNYSAVAGECLLMRRELFLELGGFDEALTRWDDVDICLRAVQAGYLNVW
TPRARLLLDAPATTAASVEEEDALYTRWLPLLARDPAYNPGFSLQAEGGFKLADPQLAWRPLQGWRPCPLSGAPRRPIRL
RPLPGDPAVQHVARVGIHRWRAVDRPDARGRSGALRPGRTGAAAPGRRGASRGHAADAGVLAGLQGLRAGRLSAQRAPQE
RPSPAPAEGHFAHAASRAGLRRPLRGVDAGPGRGLRRSPPGYPGDREPPAGGVVAGAAGAAAARRAATCRLGGRLEPYRR
SGTDRRCGPGTGRRSRLGVLRHVPAVHPSLRQGSACGGAYRTLSAGIGGSRSRPGAGAGGAEPVQRVQEQSAPAGIRRLR
FPGGLQRRALLPGRSDR
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