PAI Gene Information


Name : unnamed
Accession : AAK00485.1
PAI name : SHI-1
PAI accession : AF200692
Strain : Shigella flexneri 2002017
Virulence or Resistance: Not determined
Product : unknown
Function : -
Note : ORF31
Homologs in the searched genomes :   119 hits    ( 116 protein-level,   3 DNA-level )  
Publication :
    -Al-Hasani,K., Henderson,I.R., Sakellaris,H., Rajakumar,K., Grant,T., Nataro,J.P., Robins-Browne,R. and Adler,B., "The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation", Infect. Immun. 68 (5), 2457-2463 (2000) PUBMED 10768931.

    -Al-Hasani,K., Rajakumar,K. and Adler,B., "Direct Submission", Submitted (01-NOV-1999) Microbiology, Monash University, Wellington Road, Clayton, Vic 3800, Australia.

    -Al-Hasani,K., Rajakumar,K., Adler,B. and Sakellaris,H., "Direct Submission", Submitted (16-JAN-2001) Microbiology, Monash University, Wellington Road, Clayton, Vic 3800, Australia REMARK Sequence update by submitter.

    -Al-Hasani,K., Rajakumar,K., Bulach,D., Robins-Browne,R., Adler,B. and Sakellaris,H., "Genetic organization of the she pathogenicity island in Shigella flexneri 2a", Microb. Pathog. 30 (1), 1-8 (2001) PUBMED 11162180.


DNA sequence : 
ATGTCTGAAATCACAGCCTCTCGTCCGGAAGTGGTCAACGGGCATACGGACGTTATCTGCTCAACCAGTATCCGCCACAT
TCTGGCTGTACGAAAGAGTACATTGCTGCAAATCGACACACTTATCCGACAACTGGCTGAAGTATCAGCAATGACAGAAA
GTATTAGAGGTAAAACGGCTCTGGACTGGGCCATGAAACAGGATTTTCGCTGCGGTTGCTGGCTGATGGAGAAACCGGAA
ACCGCAATGAAAGCCATCACACGCAATCTTGATCGCGAACTCTGGCGTGATCTGATGCAACGTTCCGGGATGCTGAGTCT
GATGGATGCGCAGACCCGGGACACATGGTACAGGTCACTGGAATATGATAATTTTCCGGAAATCAGCGAAGCGAACATTC
TGAGCACATTTGAACAACTGCACCAGAACAAAGATGAAGTGTTTGAACGGGGAGTGATCAACGTCTTCAAAGGGCTGAGC
TGGGATTACAAAACCAACTCACCCTGTAAATTTGGCAGTAAAATTATCGTCAACAACCTGGTGAGGTGGGACCGGTGGGG
GTTTCATCTTATCACCGGGCAACAGACTGACCGACTCGTCGACCTGGAAAGAATGCTACATCTGTTCAGCGGCAAACCGA
TCCCCGACAACCGGGAAAACATCACTATTCGTCTGGATGGTCACATCCAGTCCGTTCAGGGTAAAGAGCGCTATGAAGAC
GAGATGTTCATCATTAAATACTTTAAGAAGGGATCTGCACACATCACTTTCAAAAGGCTGGAACTGATTGACAGAATTAA
CGATATAATAGCCAGGTACTTTCCTTCTGTGCTCTCAGCCTGA

Protein sequence : 
MSEITASRPEVVNGHTDVICSTSIRHILAVRKSTLLQIDTLIRQLAEVSAMTESIRGKTALDWAMKQDFRCGCWLMEKPE
TAMKAITRNLDRELWRDLMQRSGMLSLMDAQTRDTWYRSLEYDNFPEISEANILSTFEQLHQNKDEVFERGVINVFKGLS
WDYKTNSPCKFGSKIIVNNLVRWDRWGFHLITGQQTDRLVDLERMLHLFSGKPIPDNRENITIRLDGHIQSVQGKERYED
EMFIIKYFKKGSAHITFKRLELIDRINDIIARYFPSVLSA