PAI Gene Information


Name : unnamed
Accession : AAK00478.1
PAI name : SHI-1
PAI accession : AF200692
Strain : Shigella flexneri 2002017
Virulence or Resistance: Not determined
Product : unknown
Function : -
Note : ORF24
Homologs in the searched genomes :   6 hits    ( 5 protein-level,   1 DNA-level )  
Publication :
    -Al-Hasani,K., Henderson,I.R., Sakellaris,H., Rajakumar,K., Grant,T., Nataro,J.P., Robins-Browne,R. and Adler,B., "The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation", Infect. Immun. 68 (5), 2457-2463 (2000) PUBMED 10768931.

    -Al-Hasani,K., Rajakumar,K. and Adler,B., "Direct Submission", Submitted (01-NOV-1999) Microbiology, Monash University, Wellington Road, Clayton, Vic 3800, Australia.

    -Al-Hasani,K., Rajakumar,K., Adler,B. and Sakellaris,H., "Direct Submission", Submitted (16-JAN-2001) Microbiology, Monash University, Wellington Road, Clayton, Vic 3800, Australia REMARK Sequence update by submitter.

    -Al-Hasani,K., Rajakumar,K., Bulach,D., Robins-Browne,R., Adler,B. and Sakellaris,H., "Genetic organization of the she pathogenicity island in Shigella flexneri 2a", Microb. Pathog. 30 (1), 1-8 (2001) PUBMED 11162180.


DNA sequence : 
ATGCAGCATGTCCCTGAAGGCGTGATTCAGGCACCAGAATCACCCGACGCCCCGGAGGCGCTGCCGGGGTGTCGTTCCAT
TTCTGATGATGACCTGTGCGCCTGGTGTACCCGTCTGCTTTACCGTCCCGGAGAAATCAGTCTGTGCAGACTGAGTATAC
AGGCAATGGCATCTGGCCATCCGTCTGTGACCGGAACGGTTACGCGTACGGCTGTCCGGAATTTCAGCCGAATATCATTC
ATCCCTGATATTACCGGGTCATCACGGTCAGTGATGAACGTGATGTTGCCAGCTCCCGACCTTTACTCCCTCTCATTTAT
TCACATTACAAGGATTTCATACATGAAAACATTGTCTCAGAACACCACCTCTTCGGCCTGTGCACCGGAGACTGACCTGC
AACAACTGGTTGCCACCCTCGTCCCTGATGAACAGCGCATCAGCTTCTGGCCGCAGCACTTTGGCCTCATTCCACAGTGG
GTGACCCTGGAGCCCCGTGTCTTCGGCTGGATGGACCGTCTGTGCGAAAACTACTGCGGTGGTATCTGGAATCTGTACAC
CCTGAACAACGGCGGGGCATTTATGGCACCCGAACCGGATGACGATGATGACGAAACATGGGTACTGTTCAATGCCATGA
ACGGTAACCGCGCTGAAATGAGTCCGGAAGCTGCCGGCATTGCTGCCTGTCTGATGACGTACAGTCATCATGCCTGTCGT
ACGGAGTGTTATGCCATGACGGTCCATTATTACCGGCTGCGGGATTACGCCCTGCAGCATCCGGAATGCAGCGCCATTAT
GCGCATCATCGACTGA

Protein sequence : 
MQHVPEGVIQAPESPDAPEALPGCRSISDDDLCAWCTRLLYRPGEISLCRLSIQAMASGHPSVTGTVTRTAVRNFSRISF
IPDITGSSRSVMNVMLPAPDLYSLSFIHITRISYMKTLSQNTTSSACAPETDLQQLVATLVPDEQRISFWPQHFGLIPQW
VTLEPRVFGWMDRLCENYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGNRAEMSPEAAGIAACLMTYSHHACR
TECYAMTVHYYRLRDYALQHPECSAIMRIID