Name : cag-W
Accession : AAF80200.1
PAI name : cag PAI
PAI accession : AF282852
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : Cag-W
Function : -
Note : similar to VirB8; HP529; cag9; JHP478; ORF16
Homologs in the searched genomes : 46 hits ( 45 protein-level, 1 DNA-level )
Publication :
-Censini,S., Lange,C., Xiang,Z., Crabtree,J.E., Ghiara,P., Borodovsky,M., Rappuoli,R. and Covacci,A., "cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors", Proc. Natl. Acad. Sci. U.S.A. 93 (25), 14648-14653 (1996) PUBMED 8962108.
-Censini,S., Rappuoli,R. and Covacci,A., "Direct Submission", Submitted (17-MAR-2000) Molecular Biology, Chiron-Biocine, Via Fiorentina 1, Siena, SI 53100, Italy REMARK Sequence update by submitter.
-Censini,S., Rappuoli,R., Lange,C. and Covacci,A., "Direct Submission", Submitted (06-JUN-1996) Molecular Biology, Chiron-Biocine, Via Fiorentina 1, Siena, SI 53100, Italy.
-Covacci,A. and Rappuoli,R., "Tyrosine-phosphorylated bacterial proteins: Trojan horses for the host cell", J. Exp. Med. 191 (4), 587-592 (2000) PUBMED 10684850.
| DNA sequence : | |
ATGTTTAATATTAAAAGGACTTTTTTAATAACGATCATAAGTTTTTTTCTCATTGTTCCTAATTGGTTGAAAGCTATTGA
TTTGCCCATTGTTTCAAATCTCAAAATTTACCAAACAGTTTATTGCATGCTGATACCGAGTTATGTTTTAACCAACAAAA
GTTTTGCAGATATTTTGACAGGCTATACATCTATTGGTGCATCAGGGAGTGGAAAGAGTTCAGGGCAGGGTGTGATCGAA
GCGCTTAGCACACCATTAGCCACAAGTTTAGCCGCTAGCAATCTGGTGAAATATTTGAATACTTTAGGTCCTTTATGGGG
ATCGGCGTGGGCAAGTGTTGCTACAGCTATACAAGGTTTTGCTCTAACGCCATCAAGTGGCTGTAATTTTGGTTGGAACG
CATTGATAAATAAAAACATAGATGTATCCATGGATAGCGTGCTAGACAATTTGAGCAACAAGATTCAAAATTTCACCAAA
GGCGGTGTTGAGGACAATGTGAAAGGCAATATTCTTTTACAAATAATTGGCTCAATAACCGCTCAAGCTTCTACGAATAT
TACAGCTGATGGTTTAATTTGGCTGATTGGTAAAGAATTCACTGCAAATAAACTGCAAAACAACACTACAGCCATGCTTG
CTTTTGCCGCATTAGAATCTGTTGTCAAAGGAGCGGACGCTGCTGTTCTTCCTGCATATGGTGTAGTCAATCTGCCTGAT
ATTATCATAGGGCAAGGGTCATATCTTGATTTTGTTTCTTACCTGATTTATATTGTTTTTGGGATTTTTGTTTTTATTTC
TTTTATGAAATTGAGAGATATTTCAAGTAACATTCAGATTAACATAGGTTTTGAATACATGCGATTTATTGGGGGAACAT
TATTCAAAATGGCGATGGTCTCTTTTATCGCCTATGCAGGTTTTGGTTATCTTTATAAAATCTCTTATTCTATTTATTTT
GGTTTAGCAGGCACTTTTGGGCTGAATCAAGTTCTTTTTTGGGCTTTAGATTTAGTGCTGAATTACACTGTTAATTCAAT
TTTACCTGCAGTAAGAGCTGTTTTTTCTAATGTTGGCAACAACGCTCCTAGTTTGTTACAAGGCTTGCAAGTGGCAGGTA
TTTCTTTATTCGCTATTTTTATGCAAGTAACTATCATTATGAGAATAAGCACTGTGGTTGTAAAACCTTTGATAGCAGGG
GCTTTTAGCGGTATTGTGTTCCCTATTGCAGTATGTTTGATCGTGCTAGATTGGTTCAAAGATTCTATGAAAAACATATT
GATATGGTTTATTAATAATTTGTGTGTCTTGGTTCTAGCTATTCCTATTTTGCTCTTTGGTGTTTTGGCATTATTGGCAT
TCAATTTGACCATAACGCCCTCTGTTGCTATACAAAACATCAATCAAGGGGGACTAGGTATTGATTCAACTATTGCGAGT
TTGATCACTCTATTTATTTTAAAAGGTTTCATAGAGACAATTATTGAGAGTATCAATGCGATCGTTAATACCATTTTCAG
CTCTGTTTCTATGGATGGTAGCAGAATGGATAGAGAAAGAGATGCCTTAATGGTGGGAAGAGTTGGTGGATCTATGTTTA
AAGGATAA
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| Protein sequence : | |
MFNIKRTFLITIISFFLIVPNWLKAIDLPIVSNLKIYQTVYCMLIPSYVLTNKSFADILTGYTSIGASGSGKSSGQGVIE
ALSTPLATSLAASNLVKYLNTLGPLWGSAWASVATAIQGFALTPSSGCNFGWNALINKNIDVSMDSVLDNLSNKIQNFTK
GGVEDNVKGNILLQIIGSITAQASTNITADGLIWLIGKEFTANKLQNNTTAMLAFAALESVVKGADAAVLPAYGVVNLPD
IIIGQGSYLDFVSYLIYIVFGIFVFISFMKLRDISSNIQINIGFEYMRFIGGTLFKMAMVSFIAYAGFGYLYKISYSIYF
GLAGTFGLNQVLFWALDLVLNYTVNSILPAVRAVFSNVGNNAPSLLQGLQVAGISLFAIFMQVTIIMRISTVVVKPLIAG
AFSGIVFPIAVCLIVLDWFKDSMKNILIWFINNLCVLVLAIPILLFGVLALLAFNLTITPSVAIQNINQGGLGIDSTIAS
LITLFILKGFIETIIESINAIVNTIFSSVSMDGSRMDRERDALMVGRVGGSMFKG
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