Name : cag-Y
Accession : AAF80198.1
PAI name : cag PAI
PAI accession : AF282852
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : Cag-Y
Function : -
Note : similar to VirB10; HP527; cag7; JHP476; ORF13 and ORF14
Homologs in the searched genomes : 22 hits ( 21 protein-level, 1 DNA-level )
Publication :
-Censini,S., Lange,C., Xiang,Z., Crabtree,J.E., Ghiara,P., Borodovsky,M., Rappuoli,R. and Covacci,A., "cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors", Proc. Natl. Acad. Sci. U.S.A. 93 (25), 14648-14653 (1996) PUBMED 8962108.
-Censini,S., Rappuoli,R. and Covacci,A., "Direct Submission", Submitted (17-MAR-2000) Molecular Biology, Chiron-Biocine, Via Fiorentina 1, Siena, SI 53100, Italy REMARK Sequence update by submitter.
-Censini,S., Rappuoli,R., Lange,C. and Covacci,A., "Direct Submission", Submitted (06-JUN-1996) Molecular Biology, Chiron-Biocine, Via Fiorentina 1, Siena, SI 53100, Italy.
-Covacci,A. and Rappuoli,R., "Tyrosine-phosphorylated bacterial proteins: Trojan horses for the host cell", J. Exp. Med. 191 (4), 587-592 (2000) PUBMED 10684850.
| DNA sequence : | |
ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAATCCAACAAGATTCACCCCAAGATTTATCCAATGAAGAAGC
AACAGAAGCCAATCATTTTGAAGATCTTTTAAAAGAAGAAAGCTCAGACAATCATCTTGACAATTCCGCAGAAACTAAGA
GCAATTTTGATGAAGACAAGCTAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCTAGCAAT
GGCAGTCTAGCAGACAAGTTATTCAAGAAAGCCAGAAAATTAGTTGATGATAAAAGACCTTTCACTCAGCAAAAGAGTTT
AGATGAAGAAGCCCAAAAACTGAACGAAGAAGACGATCAAGAAAATAATGAGTATCAAGAAGAAACTCAAACGGGCTTAA
TTGATGATGAAACTTCTAAAAAAGCCCAACAAGATTCACCCCAAGATTCATCTAATGAAGAAGCGACAGAAGCCAATCAT
TTTGAAGATCTTTTAAAAGAAGAAAGCTCAGACAATCATCTTGACAATTCCGCAGAAACTAAGAGCAATTTTGATGAAGA
CAAGCTAGAAGAAATAACTGACGACTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGTGGCA
TTGTAGTCGCTGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTCATGCCTTTGGAAGATAAAAGC
TCTCGTTTTAGCAAAGATAGGAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAGA
ACGGAATGAAAAAGGCAATATGATCGATAAAAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTGA
ATATTGCAGAAATTGAGGACAAAAACCCATTGAGAGCCTTTTATGAGTGTATTGGTAATGGTGGCAACTATGAAGAATGT
TTGAAGCTTATCAAAGACAAAAAACTTCAAGATCAAATGAAAAAGACTCTAGAGGCTTATAACGACTGCATCAAAAATGC
TAAAACTGAAGAAGAAAGGATCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAAA
AAGTTCAAGTGGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCTTGAAACTCATAAATGAC
CCTGAGATTAGAGAGAAATTCCGTAAGGAATTAGGGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACGC
CAAAACAGAGGCTGAGAAAAATGAATGCTTGAAAGGCTTGTCTAAAGAAGCTATAGAAAGATTGAAACAGCAAGCGCTAG
ATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCTTGAAAAATATTCCCCAAGACTTGCAAAAAGAACTA
CTAGCTGATATGAGCGTCAAGGCTTATAAGGACTGCGTTTCAAAAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAA
ATTGCTCACGCCTGAAGCGAGGAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAAC
GAAAAAAGTGTTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGCCTGAAAGCTTATAAAGAT
TGCGTATCTCAAGCCAAAACCGAAGCTGAGAAAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAAAAAACTTTTAGA
AGAAGAAGCCAAAGAGAGCGTTAAAGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCG
AGAAATTACTCACCCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATCT
CAAGCCAAAACTGAAGATGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAGCAACAAGC
GCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGATAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAA
AGGTTTTAGCCAAAGAGAGCGTTAGGGTTTATTTGGATTGCGTATCAAGAGCCAAAAACGAAGCTGAAAGAAAAGAATGC
GAGAAATTACTCACCCCTGAAGCGAGAAAACTATTAGAAGAAGCTAAAAAAAGCGTTAAAGCTTATAAAGACTGCGTGTC
AAGAGCCAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTATTAGAAGAAGCTA
AAAAAAGCGTTAAAGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGATGAGAAAAAAGAATGCGAGAAATTACTC
ACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAAC
TGAAGATGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAACTTTTAGAGCAACAAGCGCTAGATTGTT
TGAAAAACGCTAAAACCGAAGCTGATAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTACAGAAAAAGGTTTTAGCT
AAAAAGAGCGTCAAGGCTTATTTAGACTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACT
CACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAA
ATGAAGAAGAAAGGAGAGCTTGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTATTAGAGGAAGCTAAAAAAAGCGTT
AAAGCTTATTTGGATTGCGTATCTCAAGCCAAAAACGAAGCTGAAAGAAAAGAATGCGAGAAATTACTCACCCCTGAAGC
GAAAAAACTTTTAGAAGAAGCTAAAGAGAGCCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAACTGAAA
GGAGAGCTTGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTATTAGAGCAAGAAGTTAAAAAGAGCGTCAAGGCTTAT
TTAGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACGCCTGAAGCAAGGAAATT
TTTAGAGAAGCAAGCATTAAGTTGTTTGGAAAAAGCTAGAAATGAAGAAGAAAGAAAAGCATGTTTTAAAAATCTTCCTA
AAGATTTACAGAAAAATGTTTTAGCTAAAGAGAGCCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAA
GAAAGGAGAGCTTGCGAGAAACTACTCACCCCTGAAGCGAGAAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGC
TTATTTGGATTGCGTTTCAAGAGCTAGGAATGAAAAAGAAAAACAGGAATGCGAGAAATTGCTCACCCCTGAAGCGAGGA
AACTTTTAGAGAAAGAACTCCAACAAAAAGATAAAGCGATAAAAGATTGCCTAAAAAACGCCGATCCTAACGACAGAGCG
GCTATCATGAAGTGTTTGGATGGTTTGAGCGATGAAGAAAAGCTTAAATATTTGCAAGAAGCTAGAGAAAAGGCTGTTGC
GGATTGTTTGGCTATGGCTAAAACCGATGAAGAAAAAAGGAAATGCCAAAACCTTTATAGTGATTTGATCCAAGAAATCC
AAAATAAAAGGGCACAGAACAAACAAAATCAATTGAGTAAAACAGAAAGGTTGCATCAAGCAAGCGAGTGCTTGGATAAC
TTAGATGACCCTACTGATCAACAAGCCATAGAGCAATGTTTAGAGGGCTTGAGCGATAGTGAAAGGGCGCTAATTCTAGG
AATTAAACGACAAGCTGATGAAGTGGATCTGATTTATAGCGATCTAAGAAACCGCAAAACCTTTGACAACATGGCGGCTA
AAGGTTATCCGTTGTTGCCAATGGATTTCAAAAATGGCGGCGATATTGCCACTATTAACGCCACTAATGTTGATGCGGAC
AAAATAGCTAGCGATAATCCTATTTATGCTTCCATAGAGCCTGACATTACCAAACAATACGAAACAGAAAAAACCATTAA
GGATAAGAATTTAGAAGCTAAATTAGCTAAGGCTTTAGGTGGCAATAAAAAAGATGACGATAAAGAAAAAAGTGAAAAAT
CCACAGCAAAAGCTAAATCAGAAAGCAATAAGATAGACAAAGATGTCGCAGAAACTGCCAAAAATATCAGTGAAATCGCT
CTTAAGAACAAAAAGGAAAAGAGTGGGGATTTTGTAGATGAAAATGGTAATCCCATTGACGATAAAAAGAAAGAAGAAAA
ACAAGATGAAACAAGCCCTGTCAAACAGGCCTTTATAGGCAAGAGTGATCCCACATTTGTTTTAGCGCAATACACCCCCA
TTGAAATCACTCTGACTTCTAAAGTAGATGCCACTCTCACAGGTATAGTGAGTGGAGTTGTAGCCAAAGATGTATGGAAC
ATGAACGGCACTATGATCTTATTAGACAAAGGCACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACGCCTAT
TATGACTCGCTTAATGATAGTCTTTACTAAAGCCATTACGCCTGATGGTGTGATAATACCTCTAGCAAACGCTCAAGCAG
CAGGCATGCTGGGTGAAGCAGGGGTAGATGGCTATGTGAATAACCACTTCATGAAGCGTATAGGCTTTGCTGTGATAGCA
AGCGTGGTTAATAGCTTCTTGCAAACTGCACCTATCATAGCTCTAGATAAACTCATAGGCCTTGGCAAAGGCAGAAGTGA
AAGGACACCTGAATTTAATTACGCTTTGGGTCAAGCTATCAATGGTAGTATGCAAAGTTCAGCCCAGATGTCTAATCAAA
TTCTAGGGCAACTGATGAATATCCCCCCAAGTTTTTATAAAAATGAGGGCGATAGTATTAAGATTCTCACAATGGACGAT
ATTGATTTTAGTGGCGTGTATGATGTTAAAATTACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACCAAAAC
TTTGTCTAGAGAACATGAAGAAATCACCACAAGCCCCAAAGGTGGCAATTAA
|
| Protein sequence : | |
MNEENDKLETSKKIQQDSPQDLSNEEATEANHFEDLLKEESSDNHLDNSAETKSNFDEDKLEETQTQMDSGGNETSESSN
GSLADKLFKKARKLVDDKRPFTQQKSLDEEAQKLNEEDDQENNEYQEETQTGLIDDETSKKAQQDSPQDSSNEEATEANH
FEDLLKEESSDNHLDNSAETKSNFDEDKLEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFMPLEDKS
SRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECIGNGGNYEEC
LKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLIND
PEIREKFRKELGLQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKEL
LADMSVKAYKDCVSKARNEKEKKECEKLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESLKAYKD
CVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVS
QAKTEDEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQKKVLAKESVRVYLDCVSRAKNEAERKEC
EKLLTPEARKLLEEAKKSVKAYKDCVSRARNEKEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEDEKKECEKLL
TPEAKKLLEEAKKSVKAYLDCVSQAKTEDEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQKKVLA
KKSVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEEAKKSV
KAYLDCVSQAKNEAERKECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNETERRACEKLLTPEARKLLEQEVKKSVKAY
LDCVSRARNEKEKQECEKLLTPEARKFLEKQALSCLEKARNEEERKACFKNLPKDLQKNVLAKESLKAYKDCLSQARNEE
ERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKLLEKELQQKDKAIKDCLKNADPNDRA
AIMKCLDGLSDEEKLKYLQEAREKAVADCLAMAKTDEEKRKCQNLYSDLIQEIQNKRAQNKQNQLSKTERLHQASECLDN
LDDPTDQQAIEQCLEGLSDSERALILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDAD
KIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSEKSTAKAKSESNKIDKDVAETAKNISEIA
LKNKKEKSGDFVDENGNPIDDKKKEEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWN
MNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIA
SVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDD
IDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN
|
|
