Name : cag-beta
Accession : AAF80195.1
PAI name : cag PAI
PAI accession : AF282852
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : Cag-beta
Function : -
Note : HP524; cag5; JHP473; ORF10; similar to VirD4
Homologs in the searched genomes : 45 hits ( 43 protein-level, 2 DNA-level )
Publication :
-Censini,S., Lange,C., Xiang,Z., Crabtree,J.E., Ghiara,P., Borodovsky,M., Rappuoli,R. and Covacci,A., "cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors", Proc. Natl. Acad. Sci. U.S.A. 93 (25), 14648-14653 (1996) PUBMED 8962108.
-Censini,S., Rappuoli,R. and Covacci,A., "Direct Submission", Submitted (17-MAR-2000) Molecular Biology, Chiron-Biocine, Via Fiorentina 1, Siena, SI 53100, Italy REMARK Sequence update by submitter.
-Censini,S., Rappuoli,R., Lange,C. and Covacci,A., "Direct Submission", Submitted (06-JUN-1996) Molecular Biology, Chiron-Biocine, Via Fiorentina 1, Siena, SI 53100, Italy.
-Covacci,A. and Rappuoli,R., "Tyrosine-phosphorylated bacterial proteins: Trojan horses for the host cell", J. Exp. Med. 191 (4), 587-592 (2000) PUBMED 10684850.
| DNA sequence : | |
ATGGAAGACTTTTTGTATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTCTTCCTATACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAACCAGCCTCAAAAGAAAA
AAAGCTTTAAAGAAATCATTATAGATGGGCTGAAAGAAAGGGTTAAAACCTTTGGCTTTTGGTTGCAAGCTATACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATCGATCGCCTGA
AAGTGATGATGATCTTTTTGATATATGGGTCTATGCGATACAAGATTTTCCTAATTACTATTTTAAAGCGCTTGGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGATATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAAACTGAAGAGAAAATGATCAAAGCCAAGCTCATCACGCCTAACAATAAAAAACGCGCCTTTGACAAACGAG
AGGTGATTGTAGGCAGGCGTGGCTTGGGGGATTTCATCGCTTACGCAGGGCAGGCGTTCATTGGCTTGATTGCTCCCACT
AGAAGCGGTAAAGGTGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGATCCTAAGGC
TGACACTATGGAGACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACCGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGGCATGGCATGGTGGCTAGTGGAGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGTTGGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTCTTTAGCAATCAAGCGCGAAATCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCTACGATG
TTTTTCATAGGTTCTATGGCAAGCGGGATCAACCTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTTTAATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGACAATCTAAGAGCACTTAGTCCTGCTACTAGAAACATGTGGAATAACT
TCAAGACAATGGGTGGCGCTAAAGAAACTTACAGCTCTGTTCAAGGGGTCTATACATCAGCGTTTGCACCTTACAATAAC
GCTATGATCAGGAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATACTAGAGCTGTTTTTCAATGTGATGATTTATAGCAATTTGATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGCTTAATGCTCATGGATGAATTCACTTTATGTGGCTATTTGGAAACC
TTTGTTAAAGCGGTAGGGATTATGGCAGAATACAACATGCGCCCCGCTTTTGTGTTTCAAAGTAAGGCGCAATTAGAGAA
TGACCCCCCACTTGGTTATGGCAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCCTTGAATATGTATTATGGGATCA
ACAACGATAATTATTATGAACATTTTGAAAAACTTTCTAAGGTGTTAGGGAAATACACAAGGCAAGATGTGAGCCGAAGC
ATTGATGACAATACAGGTAAGACCAACACTTCTATCAGCAACAAAGAGCGGTTTTTGATGACCCCCGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAGAACACGCTCAAACCAATCAAATGCCACAAGGCGCTTTACTATGATGATCCAT
TCTTCACCGATGAACTCATTAAGGTAAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTGATCAGACGACT
TTTTATGATGATTTGCAAGCCGCTAAAACCAGAGGCGAATTGAGCTATGACAAGTCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA
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| Protein sequence : | |
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKSFKEIIIDGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNRSPESDDDLFDIWVYAIQDFPNYYFKALGFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNLRALSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPDQTT
FYDDLQAAKTRGELSYDKSLVPVGSSEL
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